Study of Efficacy of Induction Chemotherapy With Gemcitabine and Carboplatin for Operable Non-small-cell Lung Cancer Before Surgery
Conditions
Lung Neoplasms
Conditions: official terms
Carcinoma, Non-Small-Cell Lung - Lung Neoplasms
Conditions: Keywords
lung cancer
Study Type
Interventional
Study Phase
Phase 2
Study Design
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Intervention
Name: gemcitabine, carboplatin Type: Drug
Name: surgery Type: Procedure
Overall Status
Recruiting
Summary
To study the activity of chemotherapy with Gemzar-carboplatin in the preoperative setting for operable stages of non-small-cell lung cancer and to identify novel molecular markers correlated with chemosensitivity and prognosis
Criteria for eligibility
Healthy Volunteers:
Maximum Age: 75 Years
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Histologically or cytologically proven, newly diagnosed primary bronchogenic non-small cell lung cancer

- Measurable or evaluable tumour on chest X-ray or CT scan.

- No multiple ipsilateral or contralateral parenchymal tumours

- Stage I(exceptT1N0),II,IIIa disease as shown by PET-CT
Location
Queen Elizabeth Hospital
Hong Kong, China
Status: Recruiting
Start Date
May 2005
Completion Date
February 2007
Sponsors
Hospital Authority, Hong Kong
Source
Hospital Authority, Hong Kong
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
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