Treatment of Hepatocellular Carcinoma With Radiofrequency Ablation (RFA) Associated With Postoperative TACE
Conditions
Cancer of Liver
Conditions: official terms
Carcinoma, Hepatocellular - Liver Neoplasms
Conditions: Keywords
radiofrequency ablation, Cancer of Liver, postoperative, transhepatic arterial chemoembolization, prospective
Study Type
Interventional
Study Phase
N/A
Study Design
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Intervention
Name: radiofrequency ablation associated with TACE Type: Procedure
Name: radiofrequency ablation only Type: Procedure
Overall Status
Recruiting
Summary
A RCT was conducted to elucidate whether the treatment outcome of HCC could be improved by RFA associated with postoperative TACE.
Detailed Description
A randomized study was conducted to elucidate whether the outcome of hepatocellular carcinoma could be improved by radiofrequency ablation associated with postoperative transhepatic arterial chemoembolization.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 75 Years
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- patients with hepatocellular,confirmed by pathological examination

- patients with a live function test showed Child A or B

- Indocyanine green test showed less than 30% after 15min,and the patients showed a tolerance of RFA and TACE

- Tumor stage is early period(according to Milan Standard),that is,the diameter of single node should be less than 5cm;the node of tumor should be less than 3 and the diameter less than 3cm.

- without metastasis in lymphnode or other organs

- written consent inform assigned

Exclusion Criteria:

- preoperative examination showed malignant thrombosis in the first class branch of portal vein or hepatic vein or vena cava

- metastatic cancer of liver

- patients with a poor tolerance of RFA and TACE

- patients received other therapies.
Location
Institute of hepatobiliary surgery
Chongqing, Chongqing, China
Status: Recruiting
Contact: Ma Kuansheng, Ph.D - 86-23-68765297 - xiaobinf@medmail.com.cn
Start Date
December 2008
Completion Date
July 2013
Sponsors
Southwest Hospital, China
Source
Southwest Hospital, China
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page