Study of Kidney Tumors in Younger Patients
Conditions
Clear Cell Sarcoma of the Kidney - Congenital Mesoblastic Nephroma - Diffuse Hyperplastic Perilobar Nephroblastomatosis - Rhabdoid Tumor of the Kidney - Stage I Renal Cell Cancer - Stage I Wilms Tumor - Stage II Renal Cell Cancer - Stage II Wilms Tumor - Stage III Renal Cell Cancer - Stage III Wilms Tumor - Stage IV Renal Cell Cancer - Stage IV Wilms Tumor - Stage V Wilms Tumor
Conditions: official terms
Carcinoma, Renal Cell - Hyperplasia - Kidney Neoplasms - Neoplasms - Nephroma, Mesoblastic - Rhabdoid Tumor - Sarcoma, Clear Cell - Wilms Tumor
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Case-Only, Time Perspective: Prospective
Intervention
Name: laboratory biomarker analysis Type: Other
Name: cytology specimen collection procedure Type: Other
Overall Status
Recruiting
Summary
This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.
Detailed Description
PRIMARY OBJECTIVES:

I. Classify patients with renal tumors by histological categorization, surgico-pathological stage, presence of metastases, age at diagnosis, tumor weight, and loss of heterozygosity for chromosomes 1p and 16q, to define eligibility for a series of therapeutic studies. (Loss of heterozygosity [LOH] testing discontinued as of April 2014) II. Maintain a biological samples bank to make specimens available to scientists to evaluate additional potential biological prognostic variables and for the conduct of other research by scientists.

SECONDARY OBJECTIVES:

I. Monitor outcome for those patients who are not eligible for a subsequent therapeutic study.

II. Describe whether the pulmonary tumor burden correlates with outcome in stage IV patients.

III. Describe the sensitivity and specificity of abdominal computed tomography (CT) by comparison with surgical and pathologic findings for identification of local tumor spread beyond the renal capsule to adjacent muscle and organs, lymph node involvement at the renal hilum and in the retroperitoneum, preoperative tumor rupture, and metastases to the liver.

IV. Compare the sensitivity and specificity of pre-operative abdominal CT scan and magnetic resonance imaging (MRI) for the identification and differentiation of nephrogenic rests and Wilms' tumor in children with multiple renal lesions.

V. Correlate the method of conception (natural vs assisted reproductive technology) with the development of Wilms' tumor.

VI. To evaluate the frequency of integrase interactor 1 (INI1) mutations in renal and extrarenal malignant rhabdoid tumor of the kidney and to determine the incidence of germline and inherited versus somatic mutations to facilitate clinical correlations on the companion study AREN0321. (INI1 testing discontinued as of April 2014)

OUTLINE:

Tumor tissue, blood, and urine samples are collected for research studies, including immunohistochemistry. CT scans and MRIs are also performed. Loss of heterozygosity analyses (chromosome 1p and 16q) are performed by extraction of DNA. DNA polymorphisms are assayed by polymerase chain reaction using standard methodology. Leftover specimens are archived for future studies. (LOH and INI1 testing discontinued as of April 2014)

Patients are followed up periodically for 5 years.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 29 Years
Minimum Age: N/A
Gender: Both
Criteria: Inclusion Criteria:

- Patients with the first occurrence of any tumor of the kidney identified on CT scan or MRI are eligible for this study; histologic diagnosis is not required prior to enrollment but is required for all patients once on study

- Eligible tumors include (but are not limited to):

- Nephroblastic tumors

- Nephroblastoma (Wilms' tumor) (favorable histology, anaplasia [diffuse, focal])

- Nephrogenic rests and nephroblastomatosis

- Cystic nephroma and cystic partially differentiated nephroblastoma

- Metanephric tumors (metanephric adenoma, metanephric adenofibroma, metanephric stromal tumor)

- Mesoblastic nephroma (cellular, classic, mixed)

- Clear cell sarcoma

- Rhabdoid tumor (any malignant rhabdoid tumor occurring outside the central nervous system [CNS])

- Renal epithelioid tumors of childhood (papillary renal cell carcinoma, medullary renal cell carcinoma, renal tumors associated with Xp11.2 translocations, oncocytic renal neoplasms after neuroblastoma)

- Angiolipoma

- Ossifying renal tumor of infancy

- Patients with the first occurrence of the following tumors are also eligible:

- Extrarenal nephroblastoma or extrarenal neprogenic rests

- Malignant rhabdoid tumor occurring anywhere outside the Central Nervous System

- Required specimens, reports, and copies of imaging studies must be available for submission or must become available during the required timeframe

- For ALL patients (with exception of bilateral, bilaterally predisposed or unilateral tumor in solitary kidney planning to enroll without biopsy), the following submissions are required:

- A complete set of recut hematoxylin and eosin (H & E) slides**

- Representative formalin-fixed paraffin-embedded tissue block or if a block is unavailable, 10 unstained slides from a representative block of tumor**

- Institutional pathology report, transmittal form and pathology checklist

- Copies of images and institutional reports of CT and/or MRI abdomen and pelvis

- Copies of images and institutional report of CT chest for all malignant tumors

- Institutional surgical report(s)

- Tissue must be from diagnosis, prior to any chemotherapy or radiation

- For patients with clinical features and required imaging findings consistent with the eligibility for the bilateral study, AREN0534 (or successor study), confirmed by central review, biopsy is not required; however, if biopsy is done, tissue must be submitted as for other renal tumors, and initial risk assignment will require pathology and surgical rapid central reviews; transmittal form and pathology checklist are also needed

- Patients with extrarenal Wilms tumor must have tumor tissue available for central review

- Patients with extra-CNS malignant rhabdoid tumor must have tumor tissue available for central review

- All patients and/or their parents or legal guardians must sign a written informed consent

- All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met
Locations
Children's Hospital of Alabama
Birmingham, Alabama, United States
Status: Recruiting
Contact: Alyssa T. Reddy - 205-934-0309
University of Alabama at Birmingham
Birmingham, Alabama, United States
Status: Recruiting
Contact: Alyssa T. Reddy - 205-934-0309
University of South Alabama
Mobile, Alabama, United States
Status: Recruiting
Contact: Felicia L. Wilson - 251-665-8000
Phoenix Childrens Hospital
Phoenix, Arizona, United States
Status: Recruiting
Contact: Jessica Boklan - 602-546-0920
University of Arizona Health Sciences Center
Tucson, Arizona, United States
Status: Recruiting
Contact: Brenda J. Wittman - 520-626-9008
Arkansas Children's Hospital
Little Rock, Arkansas, United States
Status: Recruiting
Contact: David L. Becton - 501-364-7373
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Status: Withdrawn
Southern California Permanente Medical Group
Downey, California, United States
Status: Recruiting
Contact: Robert M. Cooper - 626-564-3455
City of Hope
Duarte, California, United States
Status: Recruiting
Contact: Anna B. Pawlowska - 800-826-4673 - becomingapatient@coh.org
Loma Linda University Medical Center
Loma Linda, California, United States
Status: Recruiting
Contact: Antranik A. Bedros - 909-558-3375
Miller Children's Hospital
Long Beach, California, United States
Status: Recruiting
Contact: Amanda M. Termuhlen - 562-933-5437
Cedars-Sinai Medical Center
Los Angeles, California, United States
Status: Recruiting
Contact: Fataneh (Fae) Majlessipour - 310-423-8965
Children's Hospital Los Angeles
Los Angeles, California, United States
Status: Recruiting
Contact: Leo Mascarenhas - 323-361-4110
David Geffen School of Medicine at UCLA
Los Angeles, California, United States
Status: Recruiting
Contact: Pamela H. Kempert - 310-825-6708
Mattel Children's Hospital UCLA
Los Angeles, California, United States
Status: Recruiting
Contact: Pamela H. Kempert - 310-825-6708
Children's Hospital Central California
Madera, California, United States
Status: Recruiting
Contact: Vonda L. Crouse - 866-353-5437
Children's Hospital and Research Center at Oakland
Oakland, California, United States
Status: Recruiting
Contact: Carla B. Golden - 510-450-7600
Kaiser Permanente-Oakland
Oakland, California, United States
Status: Recruiting
Contact: Steven K. Bergstrom - 626-564-3455
Childrens Hospital of Orange County
Orange, California, United States
Status: Recruiting
Contact: Violet Shen - 714-997-3000
Lucile Packard Children's Hospital Stanford University
Palo Alto, California, United States
Status: Recruiting
Contact: Neyssa M. Marina - 650-498-7061 - clinicaltrials@med.stanford.edu
University of California at Davis Cancer Center
Sacramento, California, United States
Status: Recruiting
Contact: Jay Michael S. Balagtas - 916-734-3089
Rady Children's Hospital - San Diego
San Diego, California, United States
Status: Recruiting
Contact: William D. Roberts - 858-966-5934
University of California San Francisco Medical Center-Parnassus
San Francisco, California, United States
Status: Recruiting
Contact: Robert E. Goldsby - 877-827-3222
Santa Barbara Cottage Hospital
Santa Barbara, California, United States
Status: Recruiting
Contact: Daniel J. Greenfield - 805-682-7300
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
Torrance, California, United States
Status: Recruiting
Contact: Joseph L. Lasky - 888-662-8252
Children's Hospital Colorado
Aurora, Colorado, United States
Status: Recruiting
Contact: Timothy P. Garrington - 720-777-6672
Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center
Denver, Colorado, United States
Status: Recruiting
Contact: Jennifer J. Clark - 866-775-6246
Connecticut Children's Medical Center
Hartford, Connecticut, United States
Status: Recruiting
Contact: Michael S. Isakoff - 860-545-9981
Yale University
New Haven, Connecticut, United States
Status: Recruiting
Contact: Nina S. Kadan-Lottick - 203-785-5702
Alfred I duPont Hospital for Children
Wilmington, Delaware, United States
Status: Recruiting
Contact: Christopher N. Frantz - 302-651-5755
Children's National Medical Center
Washington, District of Columbia, United States
Status: Recruiting
Contact: Jeffrey S. Dome - 202-884-2549
Lombardi Comprehensive Cancer Center at Georgetown University
Washington, District of Columbia, United States
Status: Recruiting
Contact: Aziza T. Shad - 202-444-0381
Broward Health Medical Center
Fort Lauderdale, Florida, United States
Status: Recruiting
Contact: Hector M. Rodriguez-Cortes - 954-355-5346
Golisano Children's Hospital of Southwest Florida
Fort Myers, Florida, United States
Status: Recruiting
Contact: Emad K. Salman - 239-343-5333
Lee Memorial Health System
Fort Myers, Florida, United States
Status: Withdrawn
University of Florida
Gainesville, Florida, United States
Status: Recruiting
Contact: William B. Slayton - 352-273-8675 - trials@cancer.ufl.edu
Memorial Healthcare System - Joe DiMaggio Children's Hospital
Hollywood, Florida, United States
Status: Recruiting
Contact: Iftikhar Hanif - 954-265-2234
Nemours Children's Clinic - Jacksonville
Jacksonville, Florida, United States
Status: Recruiting
Contact: Scott M. Bradfield - 904-697-3529
Baptist Hospital of Miami
Miami, Florida, United States
Status: Recruiting
Contact: Doured Daghistani - 800-599-2456 - cancerinfo@baptisthealth.net
Miami Children's Hospital
Miami, Florida, United States
Status: Recruiting
Contact: Enrique A. Escalon - 305-662-8360
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States
Status: Recruiting
Contact: Julio C. Barredo - 866-574-5124 - Sylvester@emergingmed.com
Arnold Palmer Hospital for Children and Women
Orlando, Florida, United States
Status: Recruiting
Contact: Vincent F. Giusti - 321-841-7246
Florida Hospital
Orlando, Florida, United States
Status: Recruiting
Contact: Fouad M. Hajjar - 407-303-5623
Nemours Children's Hospital
Orlando, Florida, United States
Status: Recruiting
Contact: Ramamoorthy Nagasubramanian - 407-650-7150
Nemours Childrens Clinic - Orlando
Orlando, Florida, United States
Status: Withdrawn
UF Cancer Center at Orlando Health
Orlando, Florida, United States
Status: Withdrawn
Nemours Children's Clinic - Pensacola
Pensacola, Florida, United States
Status: Recruiting
Contact: Jeffrey H. Schwartz - 904-697-3529
All Children's Hospital
Saint Petersburg, Florida, United States
Status: Recruiting
Contact: Gregory A. Hale - 727-767-2423 - HamblinF@allkids.org
Saint Joseph Children's Hospital of Tampa
Tampa, Florida, United States
Status: Recruiting
Contact: Hardeo K. Panchoosingh - 800-882-4123
Saint Mary's Hospital
West Palm Beach, Florida, United States
Status: Recruiting
Contact: Narayana Gowda - 888-823-5923 - ctsucontact@westat.com
Children's Healthcare of Atlanta - Egleston
Atlanta, Georgia, United States
Status: Recruiting
Contact: Glen Lew - 404-785-1112
Georgia Regents University
Augusta, Georgia, United States
Status: Recruiting
Contact: Colleen H. McDonough - 706-721-1663 - cancer@georgiahealth.edu
Memorial Health University Medical Center
Savannah, Georgia, United States
Status: Recruiting
Contact: J. M. Johnston - 912-350-8568
Tripler Army Medical Center
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Tonya M. Kratovil - 808-433-6336
University of Hawaii
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Robert W. Wilkinson - 808-983-6090
Saint Luke's Mountain States Tumor Institute
Boise, Idaho, United States
Status: Recruiting
Contact: Eugenia Chang - 800-845-4624
Lurie Children's Hospital-Chicago
Chicago, Illinois, United States
Status: Recruiting
Contact: Yasmin C. Gosiengfiao - 773-880-4562
University of Chicago
Chicago, Illinois, United States
Status: Recruiting
Contact: Susan L. Cohn - 773-834-7424
University of Illinois
Chicago, Illinois, United States
Status: Recruiting
Contact: Mary L. Schmidt - 312-355-3046
Loyola University Medical Center
Maywood, Illinois, United States
Status: Recruiting
Contact: Ricarchito B. Manera - 708-226-4357
Advocate Children's Hospital-Oak Lawn
Oak Lawn, Illinois, United States
Status: Recruiting
Contact: Ammar Hayani - 800-323-8622
Advocate Lutheran General Hospital.
Park Ridge, Illinois, United States
Status: Recruiting
Contact: Jong H. Kwon - 847-384-3621
Saint Jude Midwest Affiliate
Peoria, Illinois, United States
Status: Recruiting
Contact: Karen S. Fernandez - 309-655-3258
Southern Illinois University
Springfield, Illinois, United States
Status: Recruiting
Contact: Gregory P. Brandt - 217-545-7929
Riley Hospital for Children
Indianapolis, Indiana, United States
Status: Recruiting
Contact: Robert J. Fallon - 317-274-2552
Saint Vincent Hospital and Health Services
Indianapolis, Indiana, United States
Status: Recruiting
Contact: Bassem I. Razzouk - 317-338-2194
Blank Children's Hospital
Des Moines, Iowa, United States
Status: Recruiting
Contact: Wendy L. Woods-Swafford - 515-241-6729
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Status: Recruiting
Contact: Ayman A. El-Sheikh - 800-237-1225
University of Kentucky
Lexington, Kentucky, United States
Status: Recruiting
Contact: Martha F. Greenwood - 859-257-3379
Kosair Children's Hospital
Louisville, Kentucky, United States
Status: Recruiting
Contact: Salvatore J. Bertolone - 866-530-5516 - CancerResource@nortonhealthcare.org
Children's Hospital-Main Campus
New Orleans, Louisiana, United States
Status: Recruiting
Contact: Lolie C. Yu - 504-894-5377
Ochsner Medical Center Jefferson
New Orleans, Louisiana, United States
Status: Recruiting
Contact: Craig Lotterman - 888-562-4763
Tulane University Health Sciences Center
New Orleans, Louisiana, United States
Status: Terminated
Eastern Maine Medical Center
Bangor, Maine, United States
Status: Recruiting
Contact: Sarah J. Fryberger - 207-973-4274
Maine Children's Cancer Program
Scarborough, Maine, United States
Status: Recruiting
Contact: Eric C. Larsen - 207-396-8090 - wrighd@mmc.org
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, United States
Status: Recruiting
Contact: Alan D. Friedman - 410-955-8804 - jhcccro@jhmi.edu
Sinai Hospital of Baltimore
Baltimore, Maryland, United States
Status: Recruiting
Contact: Joseph M. Wiley - 410-601-6120 - pridgely@lifebridgehealth.org
University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, United States
Status: Recruiting
Contact: Teresa A. York - 800-888-8823
Walter Reed National Military Medical Center
Bethesda, Maryland, United States
Status: Recruiting
Contact: Anne B. Warwick - 301-319-2100
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Status: Recruiting
Contact: Carlos Rodriguez-Galindo - 866-790-4500
Floating Hospital for Children at Tufts Medical Center
Boston, Massachusetts, United States
Status: Recruiting
Contact: Michael J. Kelly - 617-636-5000 - ContactUsCancerCenter@TuftsMedicalCenter.org
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, United States
Status: Recruiting
Contact: Howard J. Weinstein - 877-726-5130
Baystate Medical Center
Springfield, Massachusetts, United States
Status: Active, not recruiting
University of Massachusetts Medical School
Worcester, Massachusetts, United States
Status: Recruiting
Contact: Christopher P. Keuker - 508-856-3216 - cancer.research@umassmed.edu
C S Mott Children's Hospital
Ann Arbor, Michigan, United States
Status: Recruiting
Contact: Raymond J. Hutchinson - 800-865-1125
Saint John Hospital and Medical Center
Detroit, Michigan, United States
Status: Recruiting
Contact: Hadi Sawaf - 313-343-3166
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, United States
Status: Recruiting
Contact: Sureyya Savasan - 313-576-9363
Hurley Medical Center
Flint, Michigan, United States
Status: Recruiting
Contact: Susumu Inoue - 888-606-6556
Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids, Michigan, United States
Status: Recruiting
Contact: David S. Dickens - 616-267-1925
Bronson Methodist Hospital
Kalamazoo, Michigan, United States
Status: Recruiting
Contact: Jeffrey S. Lobel - 800-227-2345
Kalamazoo Center for Medical Studies
Kalamazoo, Michigan, United States
Status: Recruiting
Contact: Jeffrey S. Lobel - 800-227-2345
Michigan State University - Breslin Cancer Center
Lansing, Michigan, United States
Status: Recruiting
Contact: Renuka Gera - 517-334-2765
Beaumont Children's Hospital-Royal Oak
Royal Oak, Michigan, United States
Status: Recruiting
Contact: Laura K. Gowans - 248-551-7695
William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, United States
Status: Withdrawn
Children's Hospitals and Clinics of Minnesota - Minneapolis
Minneapolis, Minnesota, United States
Status: Recruiting
Contact: Bruce C. Bostrom - 612-813-5193
University of Minnesota Medical Center-Fairview
Minneapolis, Minnesota, United States
Status: Recruiting
Contact: Emily G. Greengard - 612-624-2620
Mayo Clinic
Rochester, Minnesota, United States
Status: Recruiting
Contact: Carola A. Arndt - 507-538-7623
University of Mississippi Medical Center
Jackson, Mississippi, United States
Status: Recruiting
Contact: Gail C. Megason - 601-815-6700
Columbia Regional
Columbia, Missouri, United States
Status: Recruiting
Contact: Thomas W. Loew - 573-882-7440
University of Missouri - Ellis Fischel
Columbia, Missouri, United States
Status: Withdrawn
The Childrens Mercy Hospital
Kansas City, Missouri, United States
Status: Recruiting
Contact: Maxine L. Hetherington - 816-234-3265
Cardinal Glennon Children's Medical Center
Saint Louis, Missouri, United States
Status: Recruiting
Contact: William S. Ferguson - 314-268-4000
Saint John's Mercy Medical Center
Saint Louis, Missouri, United States
Status: Recruiting
Contact: Bethany G. Sleckman - 913-948-5588
Washington University School of Medicine
Saint Louis, Missouri, United States
Status: Recruiting
Contact: David B. Wilson - 800-600-3606 - info@siteman.wustl.edu
Children's Hospital and Medical Center of Omaha
Omaha, Nebraska, United States
Status: Recruiting
Contact: Minnie Abromowitch - 402-955-3949
University of Nebraska Medical Center
Omaha, Nebraska, United States
Status: Recruiting
Contact: Minnie Abromowitch - 402-955-3949
Children's Specialty Center of Nevada II
Las Vegas, Nevada, United States
Status: Recruiting
Contact: Nik Farahana N. Rashid - 702-384-0013
Nevada Cancer Research Foundation CCOP
Las Vegas, Nevada, United States
Status: Recruiting
Contact: Nik Farahana N. Rashid - 702-384-0013
Summerlin Hospital Medical Center
Las Vegas, Nevada, United States
Status: Recruiting
Contact: Nik Farahana N. Rashid - 702-384-0013
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States
Status: Recruiting
Contact: Sara Chaffee - 800-639-6918 - cancer.research.nurse@dartmouth.edu
Hackensack University Medical Center
Hackensack, New Jersey, United States
Status: Recruiting
Contact: Burton E. Appel - 201-996-2879
Saint Barnabas Medical Center
Livingston, New Jersey, United States
Status: Terminated
Morristown Memorial Hospital
Morristown, New Jersey, United States
Status: Recruiting
Contact: Steven L. Halpern - 973-971-5900
Saint Peter's University Hospital
New Brunswick, New Jersey, United States
Status: Recruiting
Contact: Stanley Calderwood - 732-745-8600 - kcovert@saintpetersuh.com
UMDNJ - Robert Wood Johnson University Hospital
New Brunswick, New Jersey, United States
Status: Recruiting
Contact: Richard A. Drachtman - 732-235-8675
Newark Beth Israel Medical Center
Newark, New Jersey, United States
Status: Recruiting
Contact: Peri Kamalakar - 973-926-7230
Saint Joseph's Regional Medical Center
Paterson, New Jersey, United States
Status: Recruiting
Contact: Mary A. Bonilla - 973-754-2909
Overlook Hospital
Summit, New Jersey, United States
Status: Recruiting
Contact: Steven L. Halpern - 973-971-5900
University of New Mexico Cancer Center
Albuquerque, New Mexico, United States
Status: Recruiting
Contact: Koh B. Boayue - 505-272-6972
Albany Medical Center
Albany, New York, United States
Status: Recruiting
Contact: Vikramjit S. Kanwar - 518-262-3368
Montefiore Medical Center
Bronx, New York, United States
Status: Recruiting
Contact: Rosanna J. Ricafort - 718-904-2730 - aecc@aecom.yu.edu
Brooklyn Hospital Center
Brooklyn, New York, United States
Status: Withdrawn
Roswell Park Cancer Institute
Buffalo, New York, United States
Status: Recruiting
Contact: Martin L. Brecher - 877-275-7724
Winthrop University Hospital
Mineola, New York, United States
Status: Recruiting
Contact: Mark E. Weinblatt - 866-946-8476
The Steven and Alexandra Cohen Children's Medical Center of New York
New Hyde Park, New York, United States
Status: Recruiting
Contact: Arlene S. Redner - 718-470-3470
Columbia University Medical Center
New York, New York, United States
Status: Recruiting
Contact: Alice Lee - 212-305-8615
Memorial Sloan-Kettering Cancer Center
New York, New York, United States
Status: Recruiting
Contact: Peter G. Steinherz - 212-639-7202
Mount Sinai Medical Center
New York, New York, United States
Status: Recruiting
Contact: Birte Wistinghausen - 212-824-7320 - jenny.figueroa@mssm.edu
New York University Langone Medical Center
New York, New York, United States
Status: Recruiting
Contact: Linda Granowetter - 212-263-4434 - prmc.coordinator@nyumc.org
Weill Medical College of Cornell University
New York, New York, United States
Status: Recruiting
Contact: Alexander Aledo - 212-746-1848
University of Rochester
Rochester, New York, United States
Status: Recruiting
Contact: Jeffrey R. Andolina - 585-275-5830
Stony Brook University Medical Center
Stony Brook, New York, United States
Status: Recruiting
Contact: Robert I. Parker - 800-862-2215
State University of New York Upstate Medical University
Syracuse, New York, United States
Status: Recruiting
Contact: Karol H. Kerr - 315-464-5476
New York Medical College
Valhalla, New York, United States
Status: Recruiting
Contact: Mehmet F. Ozkaynak - 914-594-3794
Mission Hospital-Memorial Campus
Asheville, North Carolina, United States
Status: Recruiting
Contact: Krystal S. Bottom - 828-213-4150
University of North Carolina
Chapel Hill, North Carolina, United States
Status: Recruiting
Contact: Stuart H. Gold - 877-668-0683 - cancerclinicaltrials@med.unc.edu
Carolinas Medical Center
Charlotte, North Carolina, United States
Status: Recruiting
Contact: Joel A. Kaplan - 704-355-2884
Novant Health Presbyterian Medical Center
Charlotte, North Carolina, United States
Status: Recruiting
Contact: Paulette C. Bryant - 704-384-5369
Duke University Medical Center
Durham, North Carolina, United States
Status: Recruiting
Contact: Susan G. Kreissman - 888-275-3853
East Carolina University
Greenville, North Carolina, United States
Status: Recruiting
Contact: George E. Hucks - 252-744-2391
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Status: Recruiting
Contact: Thomas W. McLean - 336-713-6771
Sanford Medical Center-Fargo
Fargo, North Dakota, United States
Status: Recruiting
Contact: Nathan L. Kobrinsky - 701-234-6161
Children's Hospital Medical Center of Akron
Akron, Ohio, United States
Status: Recruiting
Contact: Steven J. Kuerbitz - 330-543-3193
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
Status: Recruiting
Contact: John P. Perentesis - 513-636-2799
Cleveland Clinic Foundation
Cleveland, Ohio, United States
Status: Recruiting
Contact: Margaret C. Thompson - 866-223-8100
Rainbow Babies and Childrens Hospital
Cleveland, Ohio, United States
Status: Recruiting
Contact: Yousif (Joe) H. Matloub - 216-844-5437
Nationwide Children's Hospital
Columbus, Ohio, United States
Status: Recruiting
Contact: Mark A. Ranalli - 614-722-2708
Dayton Children's Hospital
Dayton, Ohio, United States
Status: Recruiting
Contact: Emmett H. Broxson - 800-228-4055
Mercy Children's Hospital
Toledo, Ohio, United States
Status: Recruiting
Contact: Rama Jasty - 419-251-8210
The Toledo Hospital/Toledo Children's Hospital
Toledo, Ohio, United States
Status: Recruiting
Contact: Dagmar T. Stein - 419-824-1842
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
Status: Recruiting
Contact: Rene Y. McNall-Knapp - 405-271-4272 - julie-traylor@ouhsc.edu
Natalie Warren Bryant Cancer Center at Saint Francis
Tulsa, Oklahoma, United States
Status: Recruiting
Contact: Gregory B. Kirkpatrick - 918-494-2200
Legacy Emanuel Children's Hospital
Portland, Oregon, United States
Status: Recruiting
Contact: Janice F. Olson - 503-413-2560
Legacy Emanuel Hospital and Health Center
Portland, Oregon, United States
Status: Recruiting
Contact: Janice F. Olson - 503-413-2560
Oregon Health and Science University
Portland, Oregon, United States
Status: Recruiting
Contact: Suman Malempati - 503-494-1080 - trials@ohsu.edu
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, United States
Status: Recruiting
Contact: Philip M. Monteleone - 484-884-2201
Geisinger Medical Center
Danville, Pennsylvania, United States
Status: Recruiting
Contact: Jeffrey S. Taylor - 570-271-5251
Penn State Hershey Children's Hospital
Hershey, Pennsylvania, United States
Status: Recruiting
Contact: Lisa M. McGregor - 717-531-6012
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Status: Recruiting
Contact: Frank M. Balis - 215-590-2810
Saint Christopher's Hospital for Children
Philadelphia, Pennsylvania, United States
Status: Recruiting
Contact: Gregory E. Halligan - 215-427-8991
Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, United States
Status: Recruiting
Contact: Arthur K. Ritchey - 412-692-5573
Rhode Island Hospital
Providence, Rhode Island, United States
Status: Recruiting
Contact: Douglas J. Harrison - 401-444-1488
Medical University of South Carolina
Charleston, South Carolina, United States
Status: Recruiting
Contact: Jacqueline M. Kraveka - 843-792-9321
Palmetto Health Richland
Columbia, South Carolina, United States
Status: Recruiting
Contact: Ronnie W. Neuberg - 803-434-3680
BI-LO Charities Children's Cancer Center
Greenville, South Carolina, United States
Status: Recruiting
Contact: Nichole L. Bryant - 864-241-6251
Greenville Cancer Treatment Center
Greenville, South Carolina, United States
Status: Recruiting
Contact: Cary E. Stroud - 864-241-6251
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, United States
Status: Recruiting
Contact: Kayelyn J. Wagner - 605-328-1367
T C Thompson Children's Hospital
Chattanooga, Tennessee, United States
Status: Active, not recruiting
East Tennessee Childrens Hospital
Knoxville, Tennessee, United States
Status: Recruiting
Contact: Ray C. Pais - 865-541-8266
St. Jude Children's Research Hospital
Memphis, Tennessee, United States
Status: Recruiting
Contact: Wayne L. Furman - 901-595-4644
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, United States
Status: Recruiting
Contact: Scott C. Borinstein - 800-811-8480
Texas Tech University Health Science Center-Amarillo
Amarillo, Texas, United States
Status: Terminated
Dell Children's Medical Center of Central Texas
Austin, Texas, United States
Status: Recruiting
Contact: Sharon K. Lockhart - 512-324-8022
Driscoll Children's Hospital
Corpus Christi, Texas, United States
Status: Recruiting
Contact: M. C. Johnson - 361-694-5311
Medical City Dallas Hospital
Dallas, Texas, United States
Status: Recruiting
Contact: Carl Lenarsky - 972-566-5588
University of Texas Southwestern Medical Center
Dallas, Texas, United States
Status: Recruiting
Contact: Naomi J. Winick - 214-648-7097
Brooke Army Medical Center
Fort Sam Houston, Texas, United States
Status: Active, not recruiting
Cook Children's Medical Center
Fort Worth, Texas, United States
Status: Recruiting
Contact: Mary Meaghan P. Granger - 682-885-2103
Baylor College of Medicine
Houston, Texas, United States
Status: Recruiting
Contact: Jodi Muscal - 713-798-1354 - burton@bcm.edu
M D Anderson Cancer Center
Houston, Texas, United States
Status: Recruiting
Contact: Najat C. Daw - 713-792-3245
Covenant Children's Hospital
Lubbock, Texas, United States
Status: Recruiting
Contact: Latha Prasannan - 806-725-8000 - jaccresearch@covhs.org
Methodist Children's Hospital of South Texas
San Antonio, Texas, United States
Status: Recruiting
Contact: Jaime Estrada - 210-575-7000
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States
Status: Recruiting
Contact: Anne-Marie R. Langevin - 210-567-0653 - che@uthscsa.edu
Scott and White Memorial Hospital
Temple, Texas, United States
Status: Recruiting
Contact: Guy H. Grayson - 254-724-5407
Primary Children's Hospital
Salt Lake City, Utah, United States
Status: Recruiting
Contact: Phillip E. Barnette - 801-585-5270
University of Vermont
Burlington, Vermont, United States
Status: Recruiting
Contact: Alan C. Homans - 802-656-8990
University of Virginia
Charlottesville, Virginia, United States
Status: Recruiting
Contact: Kimberly P. Dunsmore - 434-243-6143
Inova Fairfax Hospital
Falls Church, Virginia, United States
Status: Recruiting
Contact: Marshall A. Schorin - 703-208-6650
Childrens Hospital-King's Daughters
Norfolk, Virginia, United States
Status: Recruiting
Contact: Eric J. Lowe - 757-668-7243
Naval Medical Center - Portsmouth
Portsmouth, Virginia, United States
Status: Recruiting
Contact: Bethany M. Mikles - 757-953-5939
Virginia Commonwealth University
Richmond, Virginia, United States
Status: Recruiting
Contact: Madhu S. Gowda - 804-628-1939
Carilion Clinic Children's Hospital
Roanoke, Virginia, United States
Status: Recruiting
Contact: Mandy M. Atkinson - 540-981-7376
Seattle Children's Hospital
Seattle, Washington, United States
Status: Recruiting
Contact: Douglas S. Hawkins - 866-987-2000
Providence Sacred Heart Medical Center and Children's Hospital
Spokane, Washington, United States
Status: Recruiting
Contact: Judy L. Felgenhauer - 800-228-6618 - HopeBeginsHere@providence.org
Madigan Army Medical Center
Tacoma, Washington, United States
Status: Recruiting
Contact: Melissa A. Forouhar - 253-968-0129 - mamcdci@amedd.army.mil
Mary Bridge Children's Hospital and Health Center
Tacoma, Washington, United States
Status: Recruiting
Contact: Robert G. Irwin - 888-823-5923 - ctsucontact@westat.com
West Virginia University Charleston
Charleston, West Virginia, United States
Status: Recruiting
Contact: Allen R. Chauvenet - 304-388-9944
Saint Vincent Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: John R. Hill - 920-433-8889
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States
Status: Recruiting
Contact: Kenneth B. DeSantes - 608-262-5223
Marshfield Clinic
Marshfield, Wisconsin, United States
Status: Recruiting
Contact: Michael J. McManus - 715-389-4457
Midwest Children's Cancer Center
Milwaukee, Wisconsin, United States
Status: Recruiting
Contact: Michael E. Kelly - 414-805-4380
Sydney Children's Hospital
Randwick, New South Wales, Australia
Status: Recruiting
Contact: Draga Barbaric - (02) 9382-1721
The Children's Hospital at Westmead
Westmead, New South Wales, Australia
Status: Recruiting
Contact: Geoffrey B. McCowage - 61-2-9845 1400
Royal Brisbane and Women's Hospital
Herston, Queensland, Australia
Status: Recruiting
Contact: Helen Irving - 888-823-5923 - ctsucontact@westat.com
Royal Childrens Hospital
Herston, Queensland, Australia
Status: Recruiting
Contact: Helen Irving - 888-823-5923 - ctsucontact@westat.com
Women's and Children's Hospital-Adelaide
North Adelaide, South Australia, Australia
Status: Recruiting
Contact: Maria L. Kirby - (08) 8161 7327 - cywhs.oncsec@health.sa.gov.au
Monash Medical Center-Clayton Campus
Clayton, Victoria, Australia
Status: Recruiting
Contact: Peter A. Downie - crdo.info@mcri.edu.au
Royal Children's Hospital
Parkville, Victoria, Australia
Status: Recruiting
Contact: Francoise M. Mechinaud - crdo.info@mcri.edu.au
Princess Margaret Hospital for Children
Perth, Western Australia, Australia
Status: Recruiting
Contact: Catherine H. Cole - (08) 9340 8330 - admin@childcancerresearch.com.au
Alberta Children's Hospital
Calgary, Alberta, Canada
Status: Recruiting
Contact: Douglas R. Strother - 403-220-6898 - research4kids@ucalgary.ca
University of Alberta Hospital
Edmonton, Alberta, Canada
Status: Recruiting
Contact: Sunil Jayantilal S. Desai - 780-407-6615 - val.taylor@albertahealthservices.ca
British Columbia Children's Hospital
Vancouver, British Columbia, Canada
Status: Recruiting
Contact: Caron Strahlendorf - 604-875-2345ext6477
CancerCare Manitoba
Winnipeg, Manitoba, Canada
Status: Recruiting
Contact: Rochelle A. Yanofsky - 866-561-1026 - CIO_Web@cancercare.mb.ca
Janeway Child Health Centre
Saint John's, Newfoundland and Labrador, Canada
Status: Recruiting
Contact: Lisa Anne B. Goodyear - 866-722-1126
IWK Health Centre
Halifax, Nova Scotia, Canada
Status: Recruiting
Contact: Margaret C. Yhap - 902-470-8394
Chedoke-McMaster Hospitals
Hamilton, Ontario, Canada
Status: Recruiting
Contact: Carol Portwine - 905-521-2100ext74595
McMaster Children's Hospital at Hamilton Health Sciences
Hamilton, Ontario, Canada
Status: Recruiting
Contact: Carol Portwine - 905-521-2100ext74595
Cancer Centre of Southeastern Ontario at Kingston General Hospital
Kingston, Ontario, Canada
Status: Recruiting
Contact: Mariana P. Silva - 613-544-2630
Children's Hospital
London, Ontario, Canada
Status: Recruiting
Contact: Anne E. Cairney - 519-685-8306
Children's Hospital of Eastern Ontario
Ottawa, Ontario, Canada
Status: Recruiting
Contact: Jacqueline M. Halton - 613-738-3931
Hospital for Sick Children
Toronto, Ontario, Canada
Status: Recruiting
Contact: Ronald M. Grant - 416-813-7654ext2027 - jason.mcguire@sickkids.ca
Centre Hospitalier Universitaire Sainte-Justine
Montreal, Quebec, Canada
Status: Recruiting
Contact: Yvan Samson - 514-345-4931
The Montreal Children's Hospital of the MUHC
Montreal, Quebec, Canada
Status: Active, not recruiting
Centre Hospitalier Universitaire de Quebec
Ste-Foy, Quebec, Canada
Status: Recruiting
Contact: Bruno Michon - 418-525-4444
Allan Blair Cancer Centre
Regina, Saskatchewan, Canada
Status: Withdrawn
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, Canada
Status: Recruiting
Contact: Christopher Mpofu - 306-655-2914
Schneider Children's Medical Center of Israel
Petah Tikua, Israel
Status: Recruiting
Contact: Shoshana Revel-Vilk - 888-823-5923 - ctsucontact@westat.com
Starship Children's Hospital
Grafton, Auckland, New Zealand
Status: Recruiting
Contact: Jane E. Skeen - 0800 728 436
Christchurch Hospital
Christchurch, New Zealand
Status: Recruiting
Contact: Jane E. Skeen - 0800 728 436
San Jorge Children's Hospital
San Juan, Puerto Rico
Status: Recruiting
Contact: Luis A. Clavell - 888-823-5923 - ctsucontact@westat.com
Swiss Pediatric Oncology Group - Bern
Bern, Switzerland
Status: Terminated
Start Date
February 2006
Sponsors
Children's Oncology Group
Source
Children's Oncology Group
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page