Familial and Atypical Urothelial Cancer Registry
Conditions
Urothelial Cancer - Renal Pelvis Cancer - Ureter Cancer - Bladder Cancer
Conditions: official terms
Urinary Bladder Neoplasms
Conditions: Keywords
renal pelvis, ureter, bladder, 09-025, Renal Pelvis, Ureter, Bladder Cancer
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Case Control, Time Perspective: Prospective
Intervention
Name: saliva sample and questionaire Type: Other
Name: saliva sample, questionaire Type: Other
Overall Status
Recruiting
Summary
This study is being done to create a registry to help us learn more about urinary and other cancers. This will let us look at large groups of people who do and do not have this kind of cancer.

The investigators will look at risk factors to learn more about how these impact cancer. The investigators will also look at genetic markers. These are genes that are found in a known place. They are often associated with a particular trait. If the gene changes in some way, it may predict cancer or response to treatment. The investigators will look for markers in your saliva.

This registry will help us develop better methods of:

Preventing these cancers. Diagnosing these cancers. Treating these cancers.
Criteria for eligibility
Healthy Volunteers: Accepts Healthy Volunteers
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

Urothelial Cancer Cases

- Must be ≥ 18 years of age AND

- Must have a diagnosis of urothelial cancer AND

- Must be an English-speaker

Non-Cancer Control Group

- Must be ≥ 18 years of age AND

- Must not have cancer or a personal history of cancer, with the exception of skin cancer. AND

- Must not be a blood relative of cases AND

- Must not be a blood relative of another control AND

- Must be an English-speaker

Family Member Control Group:

In select kindreds with a high prevalence of bladder cancer and/or very early onset bladder cancer, first- and second-degree family members of probands may be contacted by the MSKCC study team and invited to complete the questionnaire and submit a saliva sample.

- Must be ≥ 18 years of age AND

- Must be a blood relative of a case participant AND

- Must be an English-speaker

Exclusion Criteria:

- Have any condition, which in the opinion of the primary MSKCC clinician or investigators precludes their ability to provide informed consent.
Locations
Memorial Sloan Kettering at Basking Ridge
Basking Ridge, New Jersey, United States
Status: Recruiting
Contact: Dean Bajorin, MD
Memorial Sloan Kettering Cancer Center @ Suffolk
Commack, New York, United States
Status: Recruiting
Contact: Dean Bajorin, MD
Memorial Sloan Kettering Cancer Center
New York, New York, United States
Status: Recruiting
Contact: Dean Bajorin, MD - 646-422-4333
Memorial Sloan Kettering Cancer Center at Mercy Medical Center
Rockville Centre, New York, United States
Status: Recruiting
Contact: Dean Bajorin, MD
Memoral Sloan Kettering Cancer Center@Phelps
Sleepy Hollow, New York, United States
Status: Recruiting
Contact: Dean Bajorin, MD
Start Date
May 2009
Completion Date
May 2016
Sponsors
Memorial Sloan Kettering Cancer Center
Source
Memorial Sloan Kettering Cancer Center
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page