Proteomics Research of Breast Cancer Markers in Interstitial Fluid and Serum
Conditions
Breast Cancer
Conditions: official terms
Breast Neoplasms
Conditions: Keywords
Proteomics, Breast Cancer Markers, Tissue Interstitial Fluid
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Case Control, Time Perspective: Prospective
Overall Status
Recruiting
Summary
The current study is a case control study involving comparisons of tissue interstitial fluid from breast cancer and adjacent non-cancerous tissue as well as that from benign breast lesion and its adjacent non-diseased tissue for a distinguishable breast cancer profile. The purpose of this research is to collect fresh breast nodule/cancer and surrounding non-cancerous tissue for proteomic studies of the interstitial fluid to identify a profile distinguishing breast cancer which will also permit future research on stored interstitial fluid, blood or tissue samples. Specific markers identified from interstitial fluid study will be investigated in blood samples to develop serum markers for breast cancer diagnosis and prognosis. Additionally, we will perform both prospective and retrospective research on breast cancer involving clinical, demographic, epidemiologic information, treatment, follow-up and outcomes on breast nodule/cancer cases collected.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- All subjects ≥ 18 years of age undergoing surgery for indeterminate breast nodules and all subjects with newly diagnosed breast cancer will be eligible to participate.

Exclusion Criteria:

- Anyone < 18 years of age.
Location
UPMC St. Margaret
Pittsburgh, Pennsylvania, United States
Status: Recruiting
Contact: Cathy Van Every, BSN - 412-781-3744 - vaneverycc@upmc.edu
Start Date
September 2009
Sponsors
University of Pittsburgh
Source
University of Pittsburgh
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page