The Development of Diagnostic Biomarker Panels for Hepatitis and Liver Cancer
Conditions
Hepatitis B,Chronic - Carcinoma,Hepatocellular
Conditions: official terms
Carcinoma, Hepatocellular - Hepatitis - Hepatitis A - Hepatitis B, Chronic
Conditions: Keywords
hepatocellular carcinoma, microarray, gene expression profiling, biomarkers
Study Type
Observational
Study Phase
N/A
Study Design
Time Perspective: Cross-Sectional
Overall Status
Recruiting
Summary
More recent studies have shown that the HBV-infected population has a greater risk of development of hepatocellular carcinoma. Nevertheless, there are still a significant number of people chronically infected by HBV who do not develop the complication. Hence, there exist biological markers that could be indicator for the disease-inducing and carcinogenic potential of the virus.
Criteria for eligibility
Healthy Volunteers: Accepts Healthy Volunteers
Maximum Age: N/A
Minimum Age: 21 Years
Gender: Both
Criteria: Inclusion Criteria:

- Patients of at least 21 years old on day of giving consent for study

- Patients must be able and wiling to give an informed consent

- Patient with chronic HBV infection

- Patient with active hepatocellular carcinoma and chronic hepatitis B

- Healthy subjects

Exclusion Criteria:

- Patients who have co-infection with HIV or chronic hepatitis C

- Subjects with other types of cancer
Locations
Sultanah Bahiyah Hospital
Alor Star, Kedah, Malaysia
Status: Recruiting
Queen Elizabeth Hospital
Kota Kinabalu, Sabah, Malaysia
Status: Recruiting
Hospital Umum Kuching Sarawak
Kuching, Sarawak, Malaysia
Status: Not yet recruiting
Selayang Hospital
Selayang, Selangor, Malaysia
Status: Recruiting
Kuala Lumpur Hospital
Kuala Lumpur, Wilayah Persekutuan, Malaysia
Status: Not yet recruiting
Island Hospital
Pulau Pinang, Malaysia
Status: Not yet recruiting
Lam Wah Ee Hospital
Pulau Pinang, Malaysia
Status: Recruiting
Penang Hospital
Pulau Pinang, Malaysia
Status: Recruiting
Start Date
August 2010
Completion Date
August 2012
Sponsors
Ministry of Health, Malaysia
Source
Ministry of Health, Malaysia
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page