Prospective Study of Active Pain Management in Lung Cancer Outpatients (APM)
Lung Cancer
Conditions: official terms
Lung Neoplasms
Conditions: Keywords
Lung cancer, Cancer pain, Opioid
Study Type
Study Phase
Phase 3
Study Design
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Supportive Care
Name: Active pain management
Type: Behavioral
Overall Status
This study is:

- A single-center, randomized, prospective controlled trial.

- To prove superiority of active pain management group compared to control group by the percent of pain intensity difference of outpatients with lung cancer pain.

- 204 patients will be recruited.
Detailed Description
- The recruited patients in both group will be provided the education about pain-killer, and received medicines including opioids according to their numeric rating scale (NRS)

- Active management group will be provided additional telephone counseling and dosage modification by specialized nurse for cancer pain.

- The percent of pain intensity difference (%PID)

- PID = (NRS of visit 1 - NRS of visit 3)/NRS of visit 1
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 80 Years
Minimum Age: 20 Years
Gender: Both
Criteria: Inclusion Criteria:

- Outpatients with lung cancer.

- The patients with uncontrolled lung cancer pain - more than and equal NRS 4 pain during previous 24 hours for background pain, or more than and equal 3 times/day for breakthrough painkiller medication.

- Over 20 year-old male or female.

- The patients can be able to received telephone counseling by investigator's decision.

Exclusion Criteria:

- Drug or alcohol abusers.

- Child-bearing women or pregnant women.

- The patients with moderate to severe psychiatric problems.

- The patients who have hypersensitivity to opioids.
Chonnam National University Hwasun Hospital
Jeonnam, Korea, Republic of
Status: Recruiting
Start Date
January 2011
Completion Date
June 2012
Chonnam National University Hospital
Chonnam National University Hospital
Record processing date processed this data on July 28, 2015 page