Impact of Sequential Chemotherapy on Young Patients Breast Cancer Treated Fertility
Conditions
Breast Cancer - Fertility
Conditions: official terms
Breast Neoplasms
Conditions: Keywords
Breast cancer, Fertility
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Overall Status
Recruiting
Summary
Per year, 52 000 women have breast cancer.7% are less than 40, and 2% are between 25 and 35. Most of them will be treated with chemotherapy.

One of the side effects is impact on the fertility. On 06/08/04 law basis, each patient is allowed to preserve gametes or germinal tissues when medical care potentially affect fertility.

Functional evaluation of ovarian reserve could help comprehend new chemotherapy protocols, provide fertility information, and help individualize fertility preservation supports.

Principal objective is to ensure the absence of ovarian stimulation's side effects and assess chemotherapy effects on child carrying potential.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 37 Years
Minimum Age: 18 Years
Gender: Female
Criteria: Inclusion Criteria:

- 18 ≤ age < 38

- breast cancer histologically proved

- under the control of an adjuvant chemotherapy or neo adjuvant chemotherapy

- verbal agreement given

Exclusion Criteria:

- age ≥ 38

- metastatic breast cancer

- non able to follow the design of the study (geographic, social or psychological reasons)
Locations
Oscar Lambret Center
Lille, Nord Pas de Calais, France
Status: Recruiting
Contact: Yvette VENDEL - +33 (0) 3.20.29.59.18 - y-vendel@o-lambret.fr
Marie Curie Center
Arras, Pas de Calais, France
Status: Recruiting
Contact: Jean-Briac PREVOST, MD - drprevost@radiopole-artois.com
Start Date
October 2011
Completion Date
October 2015
Sponsors
Centre Oscar Lambret
Source
Centre Oscar Lambret
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page