Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme
Conditions
Adult Anaplastic Astrocytoma - Adult Anaplastic Oligodendroglioma - Adult Giant Cell Glioblastoma - Adult Glioblastoma - Adult Gliosarcoma - Adult Mixed Glioma - Recurrent Adult Brain Neoplasm
Conditions: official terms
Astrocytoma - Brain Neoplasms - Glioblastoma - Gliosarcoma - Oligodendroglioma
Study Type
Interventional
Study Phase
Phase 1/Phase 2
Study Design
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Intervention
Name: Anti-Endoglin Chimeric Monoclonal Antibody TRC105 Type: Biological
Name: Bevacizumab Type: Biological
Name: Laboratory Biomarker Analysis Type: Other
Name: Pharmacological Study Type: Other
Name: Quality-of-Life Assessment Type: Other
Overall Status
Recruiting
Summary
This partially randomized phase I/II trial studies the side effects and the best dose of anti-endoglin monoclonal antibody TRC105 when given together with bevacizumab and to see how well they work in treating patients with glioblastoma multiforme that has come back. Monoclonal antibodies, such as anti-endoglin monoclonal antibody TRC105 and bevacizumab, may find tumor cells and help kill them. Giving anti-endoglin monoclonal antibody TRC105 together with bevacizumab may be an effective treatment for glioblastoma multiforme.
Detailed Description
PRIMARY OBJECTIVES:

I. To establish a maximum tolerated dose (MTD) of TRC105 (anti-endoglin monoclonal antibody TRC105) combined with bevacizumab in this patient population. (Phase I) II. To assess the safety and adverse events of TRC105 in combination with bevacizumab in this patient population. (Phase II) III. To determine the efficacy of TRC105 in combination with bevacizumab in recurrent glioblastoma as measured by progression-free survival and compare it with the efficacy of bevacizumab alone in this patient population. (Phase II)

SECONDARY OBJECTIVES:

I. To assess the proportion of patients, who are progression free at 6 months, treated with TRC105 in combination with bevacizumab as compared to bevacizumab alone. (Phase II) II. To assess the overall survival of patients treated with TRC105 in combination with bevacizumab compared to bevacizumab alone. (Phase II) III. To compare the impact of the treatment on the patients quality of life (QOL) using the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life questionnaire (QLQ)-C15-Palliative Care (PAL) and QLQ-brain neoplasm (BN)20 Patient Questionnaires. (Phase II) IV. To estimate patient recommendations for study participation to others using the Was It Worth It (WIWI) Questionnaire. (Phase II)

TERTIARY OBJECTIVES:

I. To evaluate the pharmacokinetics of TRC105. (Phase I) II. To evaluate the immunogenicity of TRC105. (Phase I) III. To determine the relationship between tumor biomarkers, circulating biomarkers of vascular response and vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) single-nucleotide polymorphisms (SNPs) in predicting efficacy and/or toxicity of treatment. (Phase II) IV. To assess the utility of magnetic resonance imaging (MRI) imaging including apparent diffusion coefficient (ADC) as a predictor of response and survival. (Phase II) V. To assess the utility of dynamic contrast enhanced (DCE) MRI as a predictor of response to bevacizumab with or without TRC105. (Phase II)

OUTLINE: This is a phase I dose-escalation study of anti-endoglin monoclonal antibody TRC105, followed by a randomized phase II study.

Phase I (closed to accrual 1/14/14): Patients receive bevacizumab intravenously (IV) over 30-90 minutes on day 1 and anti-endoglin monoclonal antibody TRC105 IV over 1-4 hours on days 8 and 11 of course 1 and days 1 and 8 of all subsequent courses. Courses repeat every 14 days in the absence of disease progression or unacceptable toxicity.

Phase II: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive bevacizumab IV over 30-90 minutes on day 1 and anti-endoglin monoclonal antibody TRC105 IV over 1-4 hours on days 8 and 11 of course 1 and days 1 and 8 of all subsequent courses. Courses repeat every 14 days in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive bevacizumab as in arm I. Courses repeat every 14 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months for 3 years.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Histological confirmation of grade 3 or 4 glioma, including astrocytoma, oligodendroglioma, and mixed gliomas, as determined by pre-registration central pathology review (Phase I)

- Histological confirmation of glioblastoma multiforme (grade 4 astrocytoma) as determined by pre-registration central pathology review; note: gliosarcomas and other grade 4 astrocytoma variants (e.g., giant cell) are eligible (Phase II)

- Evidence of tumor progression by MRI or computed tomography (CT) scan following radiation therapy or following the most recent anti-tumor therapy; note: patients who have had surgical treatment at recurrence are eligible if they had a resection with measurable or non-measurable residual disease on postoperative imaging or if there is imaging evidence of disease progression as compared to the first postoperative scan

- Measurable or evaluable disease by gadolinium MRI or contrast CT scan; note: patients who have had a gross total resection (GTR) are eligible on the basis of evaluable disease

- Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0, 1, or 2

- Absolute neutrophil count (ANC) >= 1,500/mm^3

- Platelet count >= 100,000/mm^3

- White blood cells (WBC) >= 3,000/mL

- Hemoglobin >= 10.0 g/dL; note: this level may be reached by transfusion

- Total bilirubin =< institutional upper limit of normal (ULN)

- Serum glutamic oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) =< 2 x ULN

- Creatinine =< ULN

- Life expectancy >= 12 weeks

- Negative serum pregnancy test done =< 7 days prior to registration, for women of childbearing potential only

- Urine protein creatinine (UPC) ratio < 1; note: urine protein must be screened by urine analysis for UPC ratio; for UPC ratio >= 1.0, 24-hour urine protein must be obtained and the level should be < 1,000 mg for registration

- Fixed or decreasing dose of corticosteroids (or no corticosteroids) >= 7 days prior to registration

- Calculated glomerular filtration rate (GFR) must be >= 60 ml/min; GFR will be calculated as needed per institutional guidelines

- Any number of prior chemotherapy regimens for recurrent disease (Phase I); =< 1 chemotherapy or other non-antiangiogenic regimen for recurrent disease (Phase II)

- Last dose of bevacizumab >= 2 weeks prior to registration (Phase I); note: for the phase II study only, prior exposure to bevacizumab is not allowed

- Surgery >= 4 weeks prior to registration

- Completion of radiation therapy >= 12 weeks prior to registration and prior chemotherapy >= 4 weeks prior to registration (>= 6 weeks from nitrosourea-containing regimens)

- Small molecular cell cycle inhibitors >= 2 weeks from registration

- Ability to provide informed written consent

- Ability to complete questionnaire(s) by themselves or with assistance

- Willing to return to enrolling institution for follow-up

- Willing to discontinue use of medications that inhibit platelet function >= 10 days prior to registration; aspirin at doses greater than 325 mg/day must be discontinued >= 10 days prior to registration and avoided through the study; note: nonsteroidal anti-inflammatory drug (NSAID) medications are recommended in place of aspirin; if NSAIDs or aspirin are used, histamine (H)-2 blockers and proton pump inhibitor (PPI) medications are recommended

- Willing to provide mandatory blood and tissue samples for correlative research purposes (Phase I and II)

Exclusion Criteria:

- Any of the following:

- Pregnant women

- Nursing women

- Men or women of childbearing potential who are unwilling to employ adequate contraception throughout the duration of the study and for at least 6 months after treatment has ended

- Prior hypersensitivity to bevacizumab or toxicity requiring discontinuation of bevacizumab (Phase I)

- Any prior exposure to any VEGF or VEGF inhibitor including, but not limited to, bevacizumab, cediranib, vandetanib, sunitinib, pazopanib, aflibercept, or sorafenib (Phase II)

- Prior hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies (Phase I and II)

- Prior hypersensitivity to triptan derivatives (Phase I and II)

- Other active malignancy =< 3 years prior to registration; exceptions: nonmelanotic skin cancer or carcinoma-in-situ of the cervix; note: if there is a history of prior malignancy, they must not be receiving other specific treatment (other than hormonal therapy) for their cancer

- Uncontrolled infection

- Immunocompromised patients or patients known to be human immunodeficiency virus (HIV) positive and currently receiving combination antiretroviral therapy; patients known to be HIV positive, but without clinical evidence of an immunocompromised state, are eligible for this trial

- Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would make the patient inappropriate for entry into this study or interfere significantly with the proper assessment of safety and adverse events of the prescribed regimens

- Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, or psychiatric illness/social situations that would limit compliance with study requirements

- History of hypertensive crisis or hypertensive encephalopathy

- Clinically significant cardiovascular disease defined as follows:

- Inadequately controlled hypertension (i.e., systolic blood pressure [SBP] > 160 mm Hg and/or diastolic blood pressure [DBP] > 90 mm Hg despite antihypertensive therapy)

- History of cerebrovascular accident (CVA) within 6 months

- Myocardial infarction or unstable angina within 6 months

- New York Heart Association classification II, III, or IV cardiovascular disease

- Serious and inadequately controlled cardiac arrhythmia

- Significant vascular disease (i.e., aortic aneurysm, history of aortic dissection)

- Clinically significant peripheral vascular disease

- Evidence or history of bleeding diathesis (greater than normal risk of bleeding, i.e., hereditary hemorrhagic telangiectasia type I or HHT-1) or coagulopathy in the absence of therapeutic anti-coagulation or any hemorrhage/bleeding event > grade 3 within 4 weeks prior to registration; note: patients with full-dose anticoagulants are eligible provided the patient has been on a stable dose for at least 2 weeks of low molecular weight heparin; therapeutic Coumadin and aspirin doses > 325 mg daily are not allowed

- Receiving any other investigational agent that would be considered as a treatment for the primary neoplasm

- Prior treatment with TRC105

- Serious or non-healing wound, active ulcer, or untreated bone fracture

- History of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess =< 6 months prior to registration

- History of invasive procedures defined as follows:

- Major surgical procedure, open biopsy, or significant traumatic injury =< 28 days prior to registration

- Anticipation of need for major surgical procedures during the study

- Core biopsy =< 7 days prior to registration

- History of significant vascular disease (i.e., aortic aneurysm requiring surgical repair, or recent peripheral arterial thrombosis) within 6 months prior to registration
Locations
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Status: Recruiting
Contact: Shirley S. Ong - 501-686-8274
Saint Jude Medical Center
Fullerton, California, United States
Status: Recruiting
Contact: William E. Lawler - 714-446-5642
Saint Joseph Hospital - Orange
Orange, California, United States
Status: Recruiting
Contact: Sam S. Huang - 714-541-6622
Sharp Memorial Hospital
San Diego, California, United States
Status: Recruiting
Contact: Robert M. Barone - 858-939-5015
UCSF Medical Center-Mount Zion
San Francisco, California, United States
Status: Active, not recruiting
UCSF Medical Center-Parnassus
San Francisco, California, United States
Status: Recruiting
Contact: Nicholas A. Butowski - 877-827-3222
Greenwich Hospital
Greenwich, Connecticut, United States
Status: Recruiting
Contact: Joachim M. Baehring - 203-785-5702
Saint Francis Hospital and Medical Center
Hartford, Connecticut, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Stamford Hospital/Bennett Cancer Center
Stamford, Connecticut, United States
Status: Recruiting
Contact: K.M. S. Lo - 203-323-8944
Beebe Medical Center
Lewes, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Christiana Care Health System-Christiana Hospital
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Christiana Gynecologic Oncology LLC
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Delaware Clinical and Laboratory Physicians PA
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Helen F Graham Cancer Center
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Medical Oncology Hematology Consultants PA
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Regional Hematology and Oncology PA
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Beebe Health Campus
Rehoboth Beach, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Nanticoke Memorial Hospital
Seaford, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Mayo Clinic in Florida
Jacksonville, Florida, United States
Status: Recruiting
Contact: Evanthia Galanis - 507-538-7623
Mount Sinai Medical Center
Miami Beach, Florida, United States
Status: Recruiting
Contact: Jose Lutzky - 305-674-2625 - info@msccop.com
Florida Hospital Orlando
Orlando, Florida, United States
Status: Recruiting
Contact: Lee M. Zehngebot - 407-303-5623
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Kootenai Medical Center
Coeur D'Alene, Idaho, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Kootenai Cancer Center
Post Falls, Idaho, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Kootenai Cancer
Sandpoint, Idaho, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Illinois CancerCare-Bloomington
Bloomington, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Saint Joseph Medical Center
Bloomington, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Canton
Canton, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Memorial Hospital of Carbondale
Carbondale, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Carthage
Carthage, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Centralia Oncology Clinic
Centralia, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Northwestern University
Chicago, Illinois, United States
Status: Active, not recruiting
Cancer Care Center of Decatur
Decatur, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Decatur Memorial Hospital
Decatur, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Crossroads Cancer Center
Effingham, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Eureka
Eureka, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, United States
Status: Recruiting
Contact: Nina L. Martinez - 847-570-2109
Illinois CancerCare Galesburg
Galesburg, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Western Illinois Cancer Treatment Center
Galesburg, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
NorthShore University HealthSystem-Glenbrook Hospital
Glenview, Illinois, United States
Status: Recruiting
Contact: Nina L. Martinez - 847-570-2109
Hematology Oncology Associates of Illinois-Highland Park
Highland Park, Illinois, United States
Status: Active, not recruiting
NorthShore University HealthSystem-Highland Park Hospital
Highland Park, Illinois, United States
Status: Recruiting
Contact: Nina L. Martinez - 847-570-2109
Presence Saint Mary's Hospital
Kankakee, Illinois, United States
Status: Active, not recruiting
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
NorthShore Hematology Oncology-Libertyville
Libertyville, Illinois, United States
Status: Active, not recruiting
Illinois CancerCare-Macomb
Macomb, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Garneau, Stewart C MD (UIA Investigator)
Moline, Illinois, United States
Status: Recruiting
Contact: David M. Spector - 309-779-4200
Spector, David MD (UIA Investigator)
Moline, Illinois, United States
Status: Recruiting
Contact: David M. Spector - 309-779-4200
Trinity Medical Center
Moline, Illinois, United States
Status: Recruiting
Contact: David M. Spector - 309-779-4200
Illinois Cancer Specialists-Niles
Niles, Illinois, United States
Status: Active, not recruiting
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Radiation Oncology of Northern Illinois
Ottawa, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Pekin
Pekin, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Pekin Cancer Treatment Center
Pekin, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Peoria
Peoria, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Methodist Medical Center of Illinois
Peoria, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
OSF Saint Francis Medical Center
Peoria, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC
Peoria, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Peru
Peru, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Valley Radiation Oncology
Peru, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Princeton
Princeton, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Hematology Oncology Associates of Illinois - Skokie
Skokie, Illinois, United States
Status: Active, not recruiting
Central Illinois Hematology Oncology Center
Springfield, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Memorial Medical Center
Springfield, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Southern Illinois University School of Medicine
Springfield, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Springfield Clinic
Springfield, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Cancer Care Specialists of Illinois-Swansea
Swansea, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Michiana Hematology Oncology PC-Crown Point
Crown Point, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Elkhart Clinic
Elkhart, Indiana, United States
Status: Terminated
Elkhart General Hospital
Elkhart, Indiana, United States
Status: Terminated
Michiana Hematology Oncology PC-Elkhart
Elkhart, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, United States
Status: Recruiting
Contact: Stephanie A. Wagner - 317-274-2552
Community Howard Regional Health
Kokomo, Indiana, United States
Status: Terminated
IU Health La Porte Hospital
La Porte, Indiana, United States
Status: Terminated
Memorial Regional Cancer Center Day Road
Mishawaka, Indiana, United States
Status: Recruiting
Contact: Thomas J. Reid - 800-284-7370
Michiana Hematology Oncology PC-Mishawaka
Mishawaka, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Saint Joseph Regional Medical Center-Mishawaka
Mishawaka, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Michiana Hematology Oncology PC-Plymouth
Plymouth, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Reid Hospital and Health Care Services
Richmond, Indiana, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Memorial Hospital of South Bend
South Bend, Indiana, United States
Status: Recruiting
Contact: Thomas J. Reid - 800-284-7370
Michiana Hematology Oncology PC-South Bend
South Bend, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Northern Indiana Cancer Research Consortium CCOP
South Bend, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
South Bend Clinic
South Bend, Indiana, United States
Status: Terminated
Michiana Hematology Oncology PC-Westville
Westville, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Mary Greeley Medical Center
Ames, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
McFarland Clinic PC-William R Bliss Cancer Center
Ames, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
Constantinou, Costas L MD (UIA Investigator)
Bettendorf, Iowa, United States
Status: Recruiting
Contact: David M. Spector - 309-779-4200
McFarland Clinic PC-Boone
Boone, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
Mercy Hospital
Cedar Rapids, Iowa, United States
Status: Recruiting
Contact: Deborah W. Wilbur - 319-363-2690
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, United States
Status: Recruiting
Contact: Deborah W. Wilbur - 319-363-2690
McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, United States
Status: Recruiting
Contact: Mohammed M. Milhem - 800-237-1225
McFarland Clinic PC-Jefferson
Jefferson, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
McFarland Clinic PC-Marshalltown
Marshalltown, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
Mercy Medical Center-Sioux City
Sioux City, Iowa, United States
Status: Terminated
Saint Luke's Regional Medical Center
Sioux City, Iowa, United States
Status: Terminated
Siouxland Regional Cancer Center
Sioux City, Iowa, United States
Status: Recruiting
Contact: Donald B. Wender - 712-252-0088
Cancer Center of Kansas - Chanute
Chanute, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas - Dodge City
Dodge City, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas - El Dorado
El Dorado, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas - Fort Scott
Fort Scott, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas-Independence
Independence, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas-Kingman
Kingman, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Lawrence Memorial Hospital
Lawrence, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas-Liberal
Liberal, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas-Manhattan
Manhattan, Kansas, United States
Status: Terminated
Cancer Center of Kansas - McPherson
McPherson, Kansas, United States
Status: Terminated
Cancer Center of Kansas - Newton
Newton, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas - Parsons
Parsons, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas - Pratt
Pratt, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas - Salina
Salina, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas - Wellington
Wellington, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Associates In Womens Health
Wichita, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas - Main Office
Wichita, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Via Christi Regional Medical Center
Wichita, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Wichita CCOP
Wichita, Kansas, United States
Status: Terminated
Cancer Center of Kansas - Winfield
Winfield, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Baptist Health Corbin
Corbin, Kentucky, United States
Status: Recruiting
Contact: Arvinda Padmanabhan - 859-260-6425
Oncology Hematology Care Inc-Crestview
Crestview Hills, Kentucky, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Hardin Memorial Hospital
Elizabethtown, Kentucky, United States
Status: Recruiting
Contact: Arvinda Padmanabhan - 859-260-6425
Baptist Health Lexington
Lexington, Kentucky, United States
Status: Recruiting
Contact: Arvinda Padmanabhan - 859-260-6425
Baptist Health Madisonville/Merle Mahr Cancer Center
Madisonville, Kentucky, United States
Status: Recruiting
Contact: Arvinda Padmanabhan - 859-260-6425
Baptist Health Paducah
Paducah, Kentucky, United States
Status: Recruiting
Contact: Arvinda Padmanabhan - 859-260-6425
Eastern Maine Medical Center
Bangor, Maine, United States
Status: Recruiting
Contact: Thomas H. Openshaw - 207-973-4274
Lafayette Family Cancer Center-EMMC
Brewer, Maine, United States
Status: Recruiting
Contact: Thomas H. Openshaw - 207-973-4274
Maine Center for Cancer Medicine-Scarborough
Scarborough, Maine, United States
Status: Recruiting
Contact: Devon L. Evans - research@newecs.org
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Status: Recruiting
Contact: Lakshmi Nayak - 877-442-3324
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, United States
Status: Recruiting
Contact: Lakshmi Nayak - 877-442-3324
Massachusetts General Hospital
Charlestown, Massachusetts, United States
Status: Recruiting
Contact: Frederick G. Barker - 617-724-8772 - barker@helix.mgh.harvard.edu
Bixby Medical Center
Adrian, Michigan, United States
Status: Terminated
Hickman Cancer Center
Adrian, Michigan, United States
Status: Recruiting
Contact: Rex B. Mowat - 800-444-3561
Saint Joseph Mercy Hospital
Ann Arbor, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Bronson Battle Creek
Battle Creek, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Oakwood Hospital and Medical Center
Dearborn, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Saint John Hospital and Medical Center
Detroit, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Genesys Hurley Cancer Institute
Flint, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Hurley Medical Center
Flint, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Mercy Health Saint Mary's
Grand Rapids, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Allegiance Health
Jackson, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Borgess Medical Center
Kalamazoo, Michigan, United States
Status: Recruiting
Contact: Raymond S. Lord - 269-373-7458
Bronson Methodist Hospital
Kalamazoo, Michigan, United States
Status: Recruiting
Contact: Raymond S. Lord - 269-373-7458
West Michigan Cancer Center
Kalamazoo, Michigan, United States
Status: Recruiting
Contact: Raymond S. Lord - 269-373-7458
Sparrow Hospital
Lansing, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Saint Mary Mercy Hospital
Livonia, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Mercy Memorial Hospital
Monroe, Michigan, United States
Status: Terminated
Toledo Clinic Cancer Centers-Monroe
Monroe, Michigan, United States
Status: Recruiting
Contact: Rex B. Mowat - 800-444-3561
Mercy Health Mercy Campus
Muskegon, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Lakeland Community Hospital
Niles, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Saint Joseph Mercy Oakland
Pontiac, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Saint Joseph Mercy Port Huron
Port Huron, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Spectrum Health Reed City Hospital
Reed City, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Saint Mary's of Michigan
Saginaw, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Marie Yeager Cancer Center
Saint Joseph, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Lakeland Hospital
St. Joseph, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Munson Medical Center
Traverse City, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Saint John Macomb-Oakland Hospital
Warren, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Ann Arbor Hematology -Oncology Associates
Ypsilanti, Michigan, United States
Status: Recruiting
Contact: Samir Narayan - 734-712-3596 - narayans@trinity-health.org
Fairview Ridges Hospital
Burnsville, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Mercy Hospital
Coon Rapids, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Essentia Health Cancer Center
Duluth, Minnesota, United States
Status: Recruiting
Contact: Bret E. Friday - 888-203-7267
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota, United States
Status: Recruiting
Contact: Bret E. Friday - 888-203-7267
Miller-Dwan Hospital
Duluth, Minnesota, United States
Status: Recruiting
Contact: Bret E. Friday - 888-203-7267
Saint Luke's Hospital of Duluth
Duluth, Minnesota, United States
Status: Recruiting
Contact: Basem S. Goueli - 888-823-5923 - ctsucontact@westat.com
Fairview-Southdale Hospital
Edina, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Unity Hospital
Fridley, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Hutchinson Area Health Care
Hutchinson, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Saint John's Hospital - Healtheast
Maplewood, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Abbott-Northwestern Hospital
Minneapolis, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Health Partners Inc
Minneapolis, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Hennepin County Medical Center
Minneapolis, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
New Ulm Medical Center
New Ulm, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
North Memorial Medical Health Center
Robbinsdale, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Mayo Clinic
Rochester, Minnesota, United States
Status: Recruiting
Contact: Evanthia Galanis - 507-538-7623
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota, United States
Status: Recruiting
Contact: Donald J. Jurgens - 877-229-4907 - coborncancercenter@centracare.com
Saint Cloud Hospital
Saint Cloud, Minnesota, United States
Status: Recruiting
Contact: Donald J. Jurgens - 877-229-4907 - coborncancercenter@centracare.com
Metro-Minnesota NCI Community Oncology Research Program
Saint Louis Park, Minnesota, United States
Status: Terminated
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Regions Hospital
Saint Paul, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
United Hospital
Saint Paul, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Saint Francis Regional Medical Center
Shakopee, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Lakeview Hospital
Stillwater, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Ridgeview Medical Center
Waconia, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Rice Memorial Hospital
Willmar, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Minnesota Oncology and Hematology PA-Woodbury
Woodbury, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Parkland Health Center-Bonne Terre
Bonne Terre, Missouri, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Saint Francis Medical Center
Cape Girardeau, Missouri, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Southeast Cancer Center
Cape Girardeau, Missouri, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Capital Region Medical Center-Goldschmidt Cancer Center
Jefferson City, Missouri, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Missouri Baptist Medical Center
Saint Louis, Missouri, United States
Status: Recruiting
Contact: Alan P. Lyss - 800-392-0936
Washington University School of Medicine
Saint Louis, Missouri, United States
Status: Recruiting
Contact: Jian L. Campian - 800-600-3606 - info@siteman.wustl.edu
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Missouri Baptist Sullivan Hospital
Sullivan, Missouri, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills, Missouri, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Billings Clinic Cancer Center
Billings, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Montana Cancer Consortium CCOP
Billings, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Saint Vincent Healthcare
Billings, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Bozeman Deaconess Hospital
Bozeman, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Benefis Healthcare- Sletten Cancer Institute
Great Falls, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Saint Peter's Community Hospital
Helena, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Kalispell Regional Medical Center
Kalispell, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Community Medical Hospital
Missoula, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Saint Patrick Hospital - Community Hospital
Missoula, Montana, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
University of Nebraska Medical Center
Omaha, Nebraska, United States
Status: Recruiting
Contact: Nicole A. Shonka - 402-559-6941 - unmcrsa@unmc.edu
New Hampshire Oncology Hematology PA-Concord
Concord, New Hampshire, United States
Status: Recruiting
Contact: Douglas J. Weckstein - 603-224-2556
New Hampshire Oncology Hematology PA-Hooksett
Hooksett, New Hampshire, United States
Status: Recruiting
Contact: Douglas J. Weckstein - 603-224-2556
LRGHealthcare-Lakes Region General Hospital
Laconia, New Hampshire, United States
Status: Recruiting
Contact: Douglas J. Weckstein - 603-224-2556
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States
Status: Active, not recruiting
Cooper Hospital University Medical Center
Camden, New Jersey, United States
Status: Recruiting
Contact: Nati Lerman - 856-325-6757
MD Anderson Cancer Center at Cooper-Voorhees
Voorhees, New Jersey, United States
Status: Recruiting
Contact: Nati Lerman - 856-325-6757
Hematology Oncology Associates of Central New York-Auburn
Auburn, New York, United States
Status: Recruiting
Contact: Jeffrey J. Kirshner - 315-472-7504
Hematology Oncology Associates of Central New York-East Syracuse
East Syracuse, New York, United States
Status: Recruiting
Contact: Jeffrey J. Kirshner - 315-472-7504
Memorial Sloan-Kettering Cancer Center
New York, New York, United States
Status: Active, not recruiting
Mount Sinai Medical Center
New York, New York, United States
Status: Recruiting
Contact: Adilia M. Hormigo - 212-824-7320 - jenny.figueroa@mssm.edu
Hematology Oncology Associates of Central New York-Onondaga Hill
Syracuse, New York, United States
Status: Recruiting
Contact: Jeffrey J. Kirshner - 315-472-7504
State University of New York Upstate Medical University
Syracuse, New York, United States
Status: Recruiting
Contact: Thomas E. Coyle - 315-464-5476
Wayne Memorial Hospital
Goldsboro, North Carolina, United States
Status: Recruiting
Contact: James N. Atkins - 919-580-0000
Kinston Medical Specialists PA
Kinston, North Carolina, United States
Status: Recruiting
Contact: Peter R. Watson - 252-559-2200
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Status: Recruiting
Contact: Glenn J. Lesser - 336-713-6771
Altru Cancer Center
Grand Forks, North Dakota, United States
Status: Recruiting
Contact: Grant R. Seeger - 701-780-6520
Strecker Cancer Center-Belpre
Belpre, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Toledo Clinic Cancer Centers-Bowling Green
Bowling Green, Ohio, United States
Status: Terminated
Adena Regional Medical Center
Chillicothe, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Oncology Hematology Care Inc - Anderson
Cincinnati, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Oncology Hematology Care Inc - Kenwood
Cincinnati, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Oncology Hematology Care Inc-Blue Ash
Cincinnati, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Oncology Hematology Care Inc-Eden Park
Cincinnati, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Oncology Hematology Care Inc-Mercy West
Cincinnati, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Columbus CCOP
Columbus, Ohio, United States
Status: Terminated
Columbus Oncology and Hematology Associates Inc
Columbus, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Doctors Hospital
Columbus, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Grant Medical Center
Columbus, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Mount Carmel Health Center West
Columbus, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Riverside Methodist Hospital
Columbus, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
The Mark H Zangmeister Center
Columbus, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Good Samaritan Hospital - Dayton
Dayton, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Miami Valley Hospital
Dayton, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Samaritan North Health Center
Dayton, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Delaware Health Center-Grady Cancer Center
Delaware, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Delaware Radiation Oncology
Delaware, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Grady Memorial Hospital
Delaware, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Oncology Hematology Care Inc-Healthplex
Fairfield, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Blanchard Valley Hospital
Findlay, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Wayne Hospital
Greenville, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Kettering Medical Center
Kettering, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Fairfield Medical Center
Lancaster, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Lima Memorial Hospital
Lima, Ohio, United States
Status: Terminated
Marietta Memorial Hospital
Marietta, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
OneHealth Marion General Hospital
Marion, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-488-2745 - sheree@columbusccop.org
Toledo Clinic Cancer Centers-Maumee
Maumee, Ohio, United States
Status: Recruiting
Contact: Rex B. Mowat - 800-444-3561
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Maumee, Ohio, United States
Status: Recruiting
Contact: Rex B. Mowat - 800-444-3561
Knox Community Hospital
Mount Vernon, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Licking Memorial Hospital
Newark, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Newark Radiation Oncology
Newark, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Saint Charles Hospital
Oregon, Ohio, United States
Status: Recruiting
Contact: Rex B. Mowat - 800-444-3561
Toledo Clinic Cancer Centers-Oregon
Oregon, Ohio, United States
Status: Terminated
Southern Ohio Medical Center
Portsmouth, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Springfield Regional Medical Center
Springfield, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-488-2745 - sheree@columbusccop.org
Flower Hospital
Sylvania, Ohio, United States
Status: Active, not recruiting
Mercy Hospital of Tiffin
Tiffin, Ohio, United States
Status: Terminated
Mercy Saint Anne Hospital
Toledo, Ohio, United States
Status: Recruiting
Contact: Rex B. Mowat - 800-444-3561
Saint Vincent Mercy Medical Center
Toledo, Ohio, United States
Status: Terminated
Toledo Clinic Cancer Centers-Toledo
Toledo, Ohio, United States
Status: Recruiting
Contact: Rex B. Mowat - 800-444-3561
Toledo Community Hospital Oncology Program CCOP
Toledo, Ohio, United States
Status: Active, not recruiting
University of Toledo
Toledo, Ohio, United States
Status: Active, not recruiting
Upper Valley Medical Center
Troy, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Fulton County Health Center
Wauseon, Ohio, United States
Status: Terminated
Saint Ann's Hospital
Westerville, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-566-3275
Genesis HealthCare System
Zanesville, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-488-2745 - sheree@columbusccop.org
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
Status: Recruiting
Contact: James D. Battiste - 405-271-4272 - julie-traylor@ouhsc.edu
Tulsa Cancer Institute
Tulsa, Oklahoma, United States
Status: Recruiting
Contact: James D. Battiste - 405-271-4272 - julie-traylor@ouhsc.edu
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, United States
Status: Recruiting
Contact: Suresh G. Nair - 610-402-2273
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, United States
Status: Recruiting
Contact: Suresh G. Nair - 610-402-2273
PinnacleHealth Cancer Center-Community Campus
Harrisburg, Pennsylvania, United States
Status: Recruiting
Contact: Irina G. Veytsman (Nureyeva) - 717-724-6765 - klitchfield@PINNACLEHEALTH.org
Reading Hospital
West Reading, Pennsylvania, United States
Status: Recruiting
Contact: Terrence P. Cescon - 610-988-9323
Greenville Health System Cancer Institute-Easley
Easley, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Andrews
Greenville, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Butternut
Greenville, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Eastside
Greenville, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Faris
Greenville, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Memorial Hospital
Greenville, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Greer
Greer, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Seneca
Seneca, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Spartanburg
Spartanburg, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Rapid City Regional Hospital
Rapid City, South Dakota, United States
Status: Recruiting
Contact: Mark T. Schroeder - 605-716-3982 - research@rcrh.org
University Medical Center Brackenridge
Austin, Texas, United States
Status: Recruiting
Contact: Brian D. Vaillant - 651-254-1517
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, United States
Status: Recruiting
Contact: Edward Pan - 214-648-7097
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, United States
Status: Recruiting
Contact: Howard Colman - 801-581-4477 - clinical.trials@hci.utah.edu
University of Virginia Cancer Center
Charlottesville, Virginia, United States
Status: Recruiting
Contact: David Schiff - 434-243-6143
Fredericksburg Oncology Inc
Fredericksburg, Virginia, United States
Status: Terminated
Gundersen Lutheran Medical Center
La Crosse, Wisconsin, United States
Status: Recruiting
Contact: Michael O. Ojelabi - 608-775-2385 - cancerctr@gundluth.org
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States
Status: Recruiting
Contact: H. I. Robins - 877-405-6866
Community Memorial Hospital
Menomonee Falls, Wisconsin, United States
Status: Recruiting
Contact: Jennifer M. Connelly - 414-805-4380
Froedtert and the Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Status: Recruiting
Contact: Jennifer M. Connelly - 414-805-4380
D N Greenwald Center
Mukwonago, Wisconsin, United States
Status: Recruiting
Contact: Timothy R. Wassenaar - 262-928-7878
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Oconomowoc Memorial Hospital-ProHealth Care Inc
Oconomowoc, Wisconsin, United States
Status: Recruiting
Contact: Timothy R. Wassenaar - 262-928-7878
Waukesha Memorial Hospital
Waukesha, Wisconsin, United States
Status: Recruiting
Contact: Timothy R. Wassenaar - 262-928-7878
Rocky Mountain Oncology
Casper, Wyoming, United States
Status: Terminated
Big Horn Basin Cancer Center
Cody, Wyoming, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Billings Clinic-Cody
Cody, Wyoming, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Welch Cancer Center
Sheridan, Wyoming, United States
Status: Recruiting
Contact: Benjamin T. Marchello - 800-648-6274
Start Date
November 2012
Sponsors
National Cancer Institute (NCI)
Source
National Cancer Institute (NCI)
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page