Treatment Effects Inclusive Cognitive Impact and Possibilities to Individually Adjusted Treatment in Patients With Intracranial Tumors With Clinical, Neuropsychological and Imaging Parameters
Conditions
Intracranial Tumor
Conditions: official terms
Brain Neoplasms
Conditions: Keywords
Glioma, Brain tumors, Brain metastases, MRI, Cognitive measurement, Neuropsychological evaluation, DW-MRI, P-MRI, MRS
Study Type
Interventional
Study Phase
N/A
Study Design
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Intervention
Name: MRI, neuropsychological evaluation, blood sampling
Type: Other
Overall Status
Recruiting
Summary
The main purposes with this trial is to investigate the potential of MRI with diffusion and blood volume, flow in brain to diagnose and to measure treatment effects in patients with intracranial tumors, especially gliomas and metastases in a prospective trial, to evaluate the possibilities to individually adjusted treatment in this category of patients depending on treatment outcomes measured by MRI, to perform clinical follow up in connection with MRI to evaluate a correlation and to perform testing of cognitive ability before, during, and after treatment and to investigate if given treatment causes any decrease in the patients habitual state.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Age 18 years or older

- Suspected primary brain tumor, verified glioblastoma or non surgically treated metastases from solid tumor

- Increasing MRI changes in patients with previous verified glioblastoma

- Be able to speak Swedish without difficulties (because of the neuropsychological investigations)

- Written informed concent

Exclusion Criteria:

- Unability to perform MRI
Location
Lund University Hospital
Lund, Sweden
Status: Recruiting
Contact: Danielle van Westen, MD, PhD - +46 46 - danielle.vanwesten@skane.se
Start Date
October 2012
Completion Date
February 2019
Sponsors
Lund University Hospital
Source
Lund University Hospital
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page