Investigation of Stem Cells in Human Lipoaspirate
Conditions
Breast Cancer
Conditions: Keywords
adipose-derived stem cells, viable ADSCs, apoptosis, necrosis, cryopreservation
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Case-Only, Time Perspective: Cross-Sectional
Overall Status
Recruiting
Summary
The overall purpose of this study is to enhance identification and isolation of ADSCs and adipocytes, to find the optimum culturing conditions to increase growth and volume of grafts, and to study the effects of cryopreservation on ADSCs and adipocytes. Fat injections are used in aesthetic surgery but tend to disassemble over time. If the investigators can enhance growth and volume of fat in culture, the investigators could use fat grafts in reconstruction of cancer and traumatic injury defects with the patients own cultured fat cells and grafts.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 70 Years
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- All adults (18-70 yrs) who have scheduled surgical lipectomy of the hips, abdomen, or thighs are prospective subjects for this study.

Exclusion Criteria:

- Pregnant women will be excluded to protect the unborn child.
Location
University of Nevada School of Medicine Patient Care Center
Las Vegas, Nevada, United States
Status: Recruiting
Contact: William A Zamboni, M.D. - wzamboni@medicine.nevada.edu
Start Date
March 2011
Completion Date
August 2018
Sponsors
University of Nevada, Las Vegas
Source
University of Nevada, Las Vegas
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page