Microsphere Localization Using PET/MRI in Patients With Liver Disease
Conditions
Liver Neoplasms
Conditions: official terms
Liver Diseases - Liver Neoplasms
Study Type
Interventional
Study Phase
N/A
Study Design
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Intervention
Name: PET/MR
Type: Device
Overall Status
Recruiting
Summary
To evaluate y90-PET/MRI (Positron Emission Tomography / Magnetic Resonance Imaging) for its potential on reporting 1) technical success of radioembolization and 2) presence of extrahepatic deposition of microspheres
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Participant must successfully complete the MRI screening form

- Participant must be scheduled to undergo radioembolization for liver disease

- Participant must be ≥ 18 years of age

- Participant must be able to understand and willing to sign an Institutional Review Board (IRB)-approved written informed consent document

Exclusion Criteria:

- Participant must not have any contraindications to MRI scanning

- Patient must not be pregnant or breastfeeding

- If agreeing to MRI contrast, participant must not have renal insufficiency (glomerular filtration rate (GFR < 30 mL/min/1.73 m2) measured within the past 60 days

- If agreeing to MRI contrast, participant must not be on dialysis

- If agreeing to MRI contrast, participant must not have had a prior allergic reaction to gadolinium-based contrast agents

- PET/MRI is not able to be scheduled within 72 hours of radioembolization
Location
Washington University School of Medicine
St. Louis, Missouri, United States
Status: Recruiting
Contact: Parag Parikh, M.D. - 314-747-9614 - pparikh@radonc.wustl.edu
Start Date
October 2012
Completion Date
October 2015
Sponsors
Washington University School of Medicine
Source
Washington University School of Medicine
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page