Breast Density Change Predicting Response to Adjuvant Aromatase Inhibitor
Conditions
Invasive Breast Cancer - Estrogen Receptor Positive
Conditions: official terms
Breast Neoplasms
Conditions: Keywords
breast density change, endocrine therapy response, aromatase inhibitor
Study Type
Observational [Patient Registry]
Study Phase
N/A
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Overall Status
Not yet recruiting
Summary
Breast density change after short term use of aromatase inhibitor in postmenopausal ER positive breast cancer would predict endocrine responsiveness
Detailed Description
Inclusion criteria ER positive breast cancer Postmenopause women Older than 60yr S/P bilateral salphingo-oophorectomy No menstruation history within 1yr and FSH>30mIU/mL Ipsilateral invasive breast cancer Undergone curative resection No evidence of distant metastasis Capable of breast MRI
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 70 Years
Minimum Age: N/A
Gender: Female
Criteria: Inclusion Criteria:

- ER positive invasive breast cancer Postmenopause women age 60yrs or older s/p bilateral salphingo-oophorectomy No history of menstruation and FSH>30mIU Planned for aromatase inhibitor Unilateral breast cancer Curative resection No evidence of distant metastasis

Exclusion Criteria:

- Bilateral breast cancer Male breast cancer Acceptable for breast MRI Pregnancy or lactation
Location
Seoul National University Hospital
Seoul, Korea, Republic of
Status: Not yet recruiting
Contact: Jung-Hee Cha, MS - 82-2-2072-0694 - snuirb@gmail.com
Start Date
January 2013
Completion Date
December 2018
Sponsors
Seoul National University Hospital
Source
Seoul National University Hospital
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page