Pazopanib Hydrochloride in Treating Patients With Progressive Carcinoid Tumors
Conditions
Atypical Carcinoid Tumor - Foregut Carcinoid Tumor - Hindgut Carcinoid Tumor - Lung Carcinoid Tumor - Metastatic Carcinoid Tumor - Metastatic Digestive System Neuroendocrine Tumor G1 - Midgut Carcinoid Tumor - Recurrent Digestive System Neuroendocrine Tumor G1 - Recurrent Merkel Cell Carcinoma - Regional Digestive System Neuroendocrine Tumor G1 - Stage IIIA Merkel Cell Carcinoma - Stage IIIB Merkel Cell Carcinoma - Stage IV Merkel Cell Carcinoma - Thyroid Gland Medullary Carcinoma
Conditions: official terms
Apudoma - Carcinoid Tumor - Carcinoma - Carcinoma, Medullary - Carcinoma, Merkel Cell - Neoplasms - Neuroendocrine Tumors - Thyroid Neoplasms
Study Type
Interventional
Study Phase
Phase 2
Study Design
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Intervention
Name: Laboratory Biomarker Analysis Type: Other
Name: Pazopanib Hydrochloride Type: Drug
Name: Placebo Type: Other
Name: Quality-of-Life Assessment Type: Other
Overall Status
Recruiting
Summary
This randomized phase II trial studies how well pazopanib hydrochloride works in treating patients with carcinoid tumors that are growing, spreading, or getting worse. Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Detailed Description
PRIMARY OBJECTIVES:

I. For patients with progressive carcinoid tumors, progression-free survival (progression-free survival [PFS] defined by central review according to Response Evaluation Criteria in Solid Tumors [RECIST] 1.1) will be compared between patients randomized to treatment with pazopanib (pazopanib hydrochloride) versus placebo.

SECONDARY OBJECTIVES:

I. Overall survival will be compared between treatment arms. II. Objective response rate, duration of response, and time to treatment failure will be compared between treatment arms.

III. Progression free survival as assessed by central radiology review and local radiology review will be compared overall and within treatment arms.

IV. PFS at 6 months and 12 months will be estimated within each treatment arm. V. Safety and tolerability of treatment with pazopanib/placebo will be evaluated within each treatment arm.

VI. Biochemical response (for chromogranin A, defined as a decrease of 50% or more in chromogranin A levels from baseline and for 5-hydroxyindoleacetic acid [5-HIAA], defined as a decrease of 50% or more in urinary 5-HIAA levels from baseline) will be compared between treatment arms among patients with elevated baseline levels of chromogranin A (CGA) and 5-HIAA.

VII. PFS and other indicators of efficacy will be estimated in patients who crossover to pazopanib from placebo.

TERTIARY OBJECTIVES:

I. Average time to submission of scans to the Imaging Core Laboratory (ICL) and average ICL "turn-around" time will be estimated.

II. Discordance between the local and central radiology review in assessment of progression will be estimated.

III. The rates and quality of radiographic progression (pre-study, on-study, and post-progression) will be characterized.

IV. To assess for differences in quality of life (QOL)-related domains between the two treatment groups (pazopanib versus placebo).

V. To determine if the more brief measures of QOL-related domains provide comparable information to that which is provided by the longer assessments (European Organization for Research and Treatment of Cancer [EORTC], neuroendocrine tumors [NET]21).

VI. To provide validation data for the EORTC NET21 module in terms of responsiveness over time and differences across arms.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive pazopanib hydrochloride orally (PO) once daily (QD) on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive placebo PO QD on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. At the time of progressive disease, patients may cross-over to Arm I.

After completion of study treatment, patients are followed up every 3-6 months for 5 years.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Low- or intermediate-grade neuroendocrine carcinoma, including the following subtypes: carcinoid tumor, low- to intermediate-grade or well- to moderately-differentiated neuroendocrine carcinoma or tumor, atypical carcinoid tumor; documentation from a primary tumor or metastatic site is sufficient; patients with poorly differentiated neuroendocrine carcinoma, high-grade neuroendocrine carcinoma, adenocarcinoid tumor, or goblet cell carcinoid tumor are not eligible

- Locally unresectable or metastatic carcinoid tumors

- Patients must have histologic documentation or clinical evidence of a carcinoid tumor of primary site (including foregut, midgut, hindgut or other non-pancreatic site); tumors of unknown primary site are eligible provided the treating physician does not suspect medullary thyroid cancer, pancreatic neuroendocrine tumor, paraganglioma, or pheochromocytoma; unknown primary tumors will be classified as small bowel tumors for the purpose of stratification; functional (associated with a clinical syndrome) or nonfunctional tumors are allowed; target lesions must have shown disease progression if therapy included peptide receptor radiotherapy (PRRT) and PRRT must be completed at least 8 weeks prior to registration

- Radiological evidence for progressive disease (measureable or non-measurable) within 12 months prior to registration; patients who have received anti-tumor therapy during the past 12 months (including octreotide analogs) must have had radiological documentation of progression of disease while on or after receiving therapy

- No known endobronchial lesions and/or lesions infiltrating major pulmonary vessels that increase the risk of pulmonary hemorrhage; patients with lesions infiltrating major pulmonary vessels (contiguous tumor and vessels) are excluded; however, the presence of a tumor that is touching, but not infiltrating (abutting) the vessels is acceptable (computed tomography [CT] with contrast is strongly recommended to evaluate such lesions); patients with large protruding endobronchial lesions in the main or lobar brochi are excluded; however, endobronchial lesions in the segmented bronchi are allowed

- Patients must have measurable disease per RECIST 1.1 by computed tomography (CT) scan or magnetic resonance imaging (MRI); lesions must be accurately measured in at least one dimension (longest diameter to be recorded) as >= 1 cm with CT or MRI (or >= 1.5 cm for lymph nodes)

- No prior treatment with an inhibitor of vascular endothelial growth factor (VEGF) or vascular endothelial growth factor receptor (VEGFR)

- Prior treatment (somatostatin analogs excepted) must be completed at least 2 weeks prior to registration; in addition, prior treatment (somatostatin analogs excepted) must be completed at least 4 weeks prior to initiation of study drug; treatment-related toxicities must have improved to =< grade 1 prior to registration, with the exception of alopecia

- Concurrent use of somatostatin analogs (SSTa) is allowed, provided that the patient is on a stable dose for at least two months and progressive disease on somatostatin analog has been documented; progression on octreotide is required for patients with tumors arising in the midgut

- Prior treatment with embolization (including bland embolization, chemoembolization, and selective internal radiation therapy) or ablative therapies is allowed if measurable disease remains outside of the treated area or there is documented disease progression in a treated site; there is no limit on the prior number of procedures; prior liver-directed or other ablative treatment must be completed at least 8 weeks prior to registration

- Patients should have completed any major surgery >= 4 weeks prior to registration and must have completed any minor surgery >= 2 weeks prior to registration; patients must have fully recovered from the procedure

- The following are examples of procedures considered to be minor: port placement, laparoscopy, thoracoscopy, bronchoscopy, mediastinoscopy, skin biopsies, incisional biopsies, imaging-guided biopsy for diagnostic purposes, and dental extraction procedures

- Insertion of a vascular access device, thoracentesis, paracentesis, and endoscopic ultrasonographic procedures are not considered to be major or minor surgeries

- No concurrent condition resulting in immune compromise, including chronic treatment with corticosteroids or other immunosuppressive agents

- No clinical evidence of central nervous system (CNS) metastases (including carcinomatous meningitis) at baseline, with the exception of those patients who have previously-treated CNS metastases (surgery +/- radiotherapy, radiosurgery, or gamma knife) and who meet both of the following criteria: a) are asymptomatic and b) had no requirement for steroids or enzyme-inducing anticonvulsants within 6 months prior to registration

- No history of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within 28 days prior to registration

- No clinically significant gastrointestinal abnormalities that may increase the risk for gastrointestinal bleeding within 28 days prior to registration including, but not limited to:

- Active peptic ulcer

- Known endoluminal metastatic lesion(s) with history of bleeding

- Inflammatory bowel disease (e.g. ulcerative colitis, Crohn's disease), or other gastrointestinal conditions with increased risk of perforation

- No history of serious (i.e., requiring active medical therapy with medication or medical device under the supervision of a physician) non-healing wound, ulcer, trauma, or bone fracture within 28 days prior to study entry

- Patients with a history of hypertension must have blood pressure that is adequately controlled on antihypertensives; (< 140/90 mmHg)

- No symptomatic congestive heart failure (New York Heart Association class II, III, or IV) within 6 months prior to registration

- No arterial thrombotic events within 6 months of registration, including transient ischemic attack (TIA), cerebrovascular accident (CVA), peripheral arterial thrombus, myocardial infarction (MI), or unstable angina or angina requiring surgical or medical intervention in 6 months prior to registration; patients with clinically significant peripheral artery disease (i.e., claudication on less than one block) are ineligible; patients who have experienced a deep venous thrombosis or pulmonary embolus within 6 months prior to registration must be on stable therapeutic anticoagulation for at least 6 weeks prior to enrollment of this study

- Patients on therapeutic anticoagulation with low molecular weight heparins, fondaparinux, rivaroxaban or warfarin are eligible, provided that they are on a stable dose of anticoagulants; patients who are currently receiving antiplatelet therapy of prasugrel or clopidogrel or antiaggregation agents (e.g., eptifibatide, epoprostenol, dipyridamole) or low doses of acetylsalicylic acid (up to 100 mg daily) are also eligible

- No ongoing cardiac dysrhythmias, atrial fibrillation, or prolongation of corrected QT (QTc) interval to > 480 msec

- No evidence of active bleeding, bleeding diathesis, or hemoptysis (>= 1/2 teaspoon of red blood) within 8 weeks prior to registration

- No currently unstable angina and/or uncontrolled cardiac arrhythmias

- Patients with symptomatic peripheral vascular disease are ineligible

- Ejection fraction on echocardiogram (Echo) or multi gated acquisition scan (MUGA) > 50%

- Chronic concomitant treatment with strong inhibitors of cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) is not allowed on this trial; patients on strong CYP3A4 inhibitors must discontinue the drug 14 days prior to the start of study treatment

- Women must not be pregnant or nursing; women of child bearing potential must have a negative serum or urine pregnancy test (minimum sensitivity 25 IU/L or equivalent units of human chorionic gonadotropin [HCG]) within 72 hours prior to registration; women of child-bearing potential include any female who has experienced menarche and who has not undergone surgical sterilization (hysterectomy, bilateral tubal ligation or bilateral oophorectomy) or is not postmenopausal (defined as amenorrhea >= 12 consecutive months; or women on hormone replacement therapy [HRT] with documented serum follicle stimulating hormone [FSH] level > 35 mIU/mL)

- Eastern Cooperative Oncology Group (ECOG) performance status 0-1

- Granulocytes >= 1,500/mcL

- Platelets >= 100,000/mcL

- International normalized ratio (INR) =< 1.2 X upper limit of normal (ULN); only required for patients receiving anticoagulant therapy; patients are eligible if their INR is stable and within the recommended range for the desired level of anticoagulation

- QTc =< 480 msecs

- Thyroid stimulating hormone (TSH) within normal limits (WNL); medications for thyroid dysfunction are allowed as long as TSH is normal at registration; in patients with abnormal TSH, if the free thryoxine (free T4) and free thyroxine index (FTI) are normal and patient is clinically euthyroid, patient is eligible

- Bilirubin =< 1.5 x ULN

- Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase [SGOT]) & alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x ULN; concomitant elevations in bilirubin and AST/ALT above 1.0 X ULN are NOT permitted; also, if liver metastases are present, AST & ALT =< 5 x ULN is allowed

- Serum creatinine =< 1.5 x ULN

- Urine protein to creatinine (UPC) ratio < 1, or, 24-hour urine protein < 1 g; if UPC >= 1, then a 24-hour urine protein must be assessed; patients must have a 24-hour urine protein value < 1 g to be eligible; use of urine dipstick for renal function assessment is not acceptable
Locations
Alaska Breast Care and Surgery LLC
Anchorage, Alaska, United States
Status: Active, not recruiting
Alaska Women's Cancer Care
Anchorage, Alaska, United States
Status: Active, not recruiting
Anchorage Oncology Centre
Anchorage, Alaska, United States
Status: Active, not recruiting
Katmai Oncology Group
Anchorage, Alaska, United States
Status: Active, not recruiting
Providence Alaska Medical Center
Anchorage, Alaska, United States
Status: Active, not recruiting
Mayo Clinic in Arizona
Scottsdale, Arizona, United States
Status: Recruiting
Contact: Timothy J. Hobday - 507-538-7623
Kaiser Permanente-Baldwin Park
Baldwin Park, California, United States
Status: Active, not recruiting
Cedars-Sinai Medical Center
Los Angeles, California, United States
Status: Recruiting
Contact: Andrew E. Hendifar - 310-423-8965
Los Angeles County-USC Medical Center
Los Angeles, California, United States
Status: Active, not recruiting
USC / Norris Comprehensive Cancer Center
Los Angeles, California, United States
Status: Recruiting
Contact: Syma Iqbal - 323-865-0451
Palo Alto Medical Foundation Health Care
Palo Alto, California, United States
Status: Recruiting
Contact: David S. Leibowitz - 415-209-2686 - bernicl@sutterhealth.org
Stanford Cancer Institute
Palo Alto, California, United States
Status: Active, not recruiting
Kaiser Permanente-San Diego Mission
San Diego, California, United States
Status: Active, not recruiting
Kaiser Permanente-San Diego Zion
San Diego, California, United States
Status: Active, not recruiting
UCSF Medical Center-Mission Bay
San Francisco, California, United States
Status: Recruiting
Contact: Emily K. Bergsland - 877-827-3222
UCSF Medical Center-Mount Zion
San Francisco, California, United States
Status: Active, not recruiting
Kaiser Permanente-San Marcos
San Marcos, California, United States
Status: Active, not recruiting
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California, United States
Status: Recruiting
Contact: Glenn D. Wong - 415-209-2686 - bernicl@sutterhealth.org
Palo Atlo Medical Foundation-Sunnyvale
Sunnyvale, California, United States
Status: Recruiting
Contact: Peter P. Yu - 415-209-2686 - bernicl@sutterhealth.org
The Medical Center of Aurora
Aurora, Colorado, United States
Status: Active, not recruiting
Boulder Community Hospital
Boulder, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Boulder
Boulder, Colorado, United States
Status: Active, not recruiting
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado, United States
Status: Recruiting
Contact: Keren Sturtz - 888-785-6789
Colorado Blood Cancer Institute
Denver, Colorado, United States
Status: Active, not recruiting
Colorado Cancer Research Program CCOP
Denver, Colorado, United States
Status: Active, not recruiting
Exempla Saint Joseph Hospital
Denver, Colorado, United States
Status: Active, not recruiting
Porter Adventist Hospital
Denver, Colorado, United States
Status: Active, not recruiting
Presbyterian - Saint Lukes Medical Center - Health One
Denver, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Midtown
Denver, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Rose
Denver, Colorado, United States
Status: Active, not recruiting
Rose Medical Center
Denver, Colorado, United States
Status: Active, not recruiting
Mercy Medical Center
Durango, Colorado, United States
Status: Active, not recruiting
Comprehensive Cancer Care and Research Institute of Colorado LLC
Englewood, Colorado, United States
Status: Active, not recruiting
Swedish Medical Center
Englewood, Colorado, United States
Status: Active, not recruiting
Front Range Cancer Specialists
Fort Collins, Colorado, United States
Status: Withdrawn
Poudre Valley Hospital
Fort Collins, Colorado, United States
Status: Recruiting
Contact: Steven R. Schuster - 507-538-7623
Mountain Blue Cancer Care Center
Golden, Colorado, United States
Status: Active, not recruiting
North Colorado Medical Center
Greeley, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Greenwood Village
Greenwood Village, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Lakewood
Lakewood, Colorado, United States
Status: Active, not recruiting
Saint Anthony Hospital
Lakewood, Colorado, United States
Status: Active, not recruiting
Littleton Adventist Hospital
Littleton, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Sky Ridge
Lone Tree, Colorado, United States
Status: Active, not recruiting
Sky Ridge Medical Center
Lone Tree, Colorado, United States
Status: Active, not recruiting
Longmont United Hospital
Longmont, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Longmont
Longmont, Colorado, United States
Status: Active, not recruiting
McKee Medical Center
Loveland, Colorado, United States
Status: Active, not recruiting
Parker Adventist Hospital
Parker, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers-Parker
Parker, Colorado, United States
Status: Active, not recruiting
Rocky Mountain Cancer Centers - Pueblo
Pueblo, Colorado, United States
Status: Active, not recruiting
Saint Mary Corwin Medical Center
Pueblo, Colorado, United States
Status: Active, not recruiting
Exempla Lutheran Medical Center
Wheat Ridge, Colorado, United States
Status: Recruiting
Contact: Keren Sturtz - 888-785-6789
Saint Francis Hospital and Medical Center
Hartford, Connecticut, United States
Status: Active, not recruiting
Beebe Medical Center
Lewes, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Christiana Care Health System-Christiana Hospital
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Christiana Gynecologic Oncology LLC
Newark, Delaware, United States
Status: Active, not recruiting
Delaware Clinical and Laboratory Physicians PA
Newark, Delaware, United States
Status: Active, not recruiting
Helen F Graham Cancer Center
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Medical Oncology Hematology Consultants PA
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Regional Hematology and Oncology PA
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Beebe Health Campus
Rehoboth Beach, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Nanticoke Memorial Hospital
Seaford, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware, United States
Status: Active, not recruiting
Moffitt Cancer Center
Tampa, Florida, United States
Status: Recruiting
Contact: Jonathan R. Strosberg - 800-456-7121 - canceranswers@moffitt.org
John B Amos Cancer Center
Columbus, Georgia, United States
Status: Active, not recruiting
Memorial University Medical Center
Savannah, Georgia, United States
Status: Active, not recruiting
Oncare Hawaii Inc-Pali Momi
Aiea, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
Pali Momi Medical Center
Aiea, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
Oncare Hawaii Inc-Kuakini
Honolulu, Hawaii, United States
Status: Active, not recruiting
Oncare Hawaii Inc-POB II
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
OnCare Hawaii-Liliha
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
Queen's Medical Center
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
Straub Clinic and Hospital
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
University of Hawaii Cancer Center
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
Castle Medical Center
Kailua, Hawaii, United States
Status: Terminated
Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue, Hawaii, United States
Status: Recruiting
Contact: Jeffrey L. Berenberg - 808-586-2979
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Kootenai Cancer Center
Post Falls, Idaho, United States
Status: Active, not recruiting
Northwestern University
Chicago, Illinois, United States
Status: Recruiting
Contact: Al B. Benson - 312-695-1301 - cancer@northwestern.edu
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States
Status: Recruiting
Contact: Manish R. Sharma - 773-834-7424
Cancer Care Center of Decatur
Decatur, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Decatur Memorial Hospital
Decatur, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Ingalls Memorial Hospital
Harvey, Illinois, United States
Status: Recruiting
Contact: Mark F. Kozloff - 708-915-4673 - clinicaltrials@ingalls.org
Loyola University Medical Center
Maywood, Illinois, United States
Status: Recruiting
Contact: Janelle M. Meyer - 708-226-4357
Good Samaritan Regional Health Center
Mount Vernon, Illinois, United States
Status: Active, not recruiting
Elkhart Clinic
Elkhart, Indiana, United States
Status: Terminated
Elkhart General Hospital
Elkhart, Indiana, United States
Status: Terminated
Michiana Hematology Oncology PC-Elkhart
Elkhart, Indiana, United States
Status: Active, not recruiting
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, United States
Status: Recruiting
Contact: Paul R. Helft - 317-274-2552
Community Howard Regional Health
Kokomo, Indiana, United States
Status: Terminated
IU Health La Porte Hospital
La Porte, Indiana, United States
Status: Terminated
Michiana Hematology Oncology PC-Mishawaka
Mishawaka, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Saint Joseph Regional Medical Center-Mishawaka
Mishawaka, Indiana, United States
Status: Active, not recruiting
Michiana Hematology Oncology PC-Plymouth
Plymouth, Indiana, United States
Status: Active, not recruiting
Reid Hospital and Health Care Services
Richmond, Indiana, United States
Status: Active, not recruiting
Memorial Hospital of South Bend
South Bend, Indiana, United States
Status: Recruiting
Contact: Robin T. Zon - 574-234-5123
Michiana Hematology Oncology PC-South Bend
South Bend, Indiana, United States
Status: Active, not recruiting
Northern Indiana Cancer Research Consortium CCOP
South Bend, Indiana, United States
Status: Active, not recruiting
South Bend Clinic
South Bend, Indiana, United States
Status: Terminated
Michiana Hematology Oncology PC-Westville
Westville, Indiana, United States
Status: Active, not recruiting
Mary Greeley Medical Center
Ames, Iowa, United States
Status: Active, not recruiting
McFarland Clinic PC-William R Bliss Cancer Center
Ames, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
Hematology Oncology Associates-Quad Cities
Bettendorf, Iowa, United States
Status: Active, not recruiting
McFarland Clinic PC-Boone
Boone, Iowa, United States
Status: Active, not recruiting
Cedar Rapids Oncology Association
Cedar Rapids, Iowa, United States
Status: Terminated
Mercy Hospital
Cedar Rapids, Iowa, United States
Status: Active, not recruiting
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, United States
Status: Active, not recruiting
Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa, United States
Status: Active, not recruiting
Mercy Cancer Center-West Lakes
Clive, Iowa, United States
Status: Active, not recruiting
Iowa Lutheran Hospital
Des Moines, Iowa, United States
Status: Active, not recruiting
Iowa Methodist Medical Center
Des Moines, Iowa, United States
Status: Active, not recruiting
Iowa Oncology Research Association CCOP
Des Moines, Iowa, United States
Status: Active, not recruiting
Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa, United States
Status: Active, not recruiting
Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa, United States
Status: Active, not recruiting
Mercy Medical Center - Des Moines
Des Moines, Iowa, United States
Status: Active, not recruiting
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, United States
Status: Recruiting
Contact: Daniel A. Vaena - 800-237-1225
McFarland Clinic PC-Jefferson
Jefferson, Iowa, United States
Status: Active, not recruiting
McFarland Clinic PC-Marshalltown
Marshalltown, Iowa, United States
Status: Active, not recruiting
Mercy Medical Center-Sioux City
Sioux City, Iowa, United States
Status: Terminated
Saint Luke's Regional Medical Center
Sioux City, Iowa, United States
Status: Terminated
Siouxland Regional Cancer Center
Sioux City, Iowa, United States
Status: Active, not recruiting
Mercy Medical Center-West Lakes
West Des Moines, Iowa, United States
Status: Active, not recruiting
Methodist West Hospital
West Des Moines, Iowa, United States
Status: Active, not recruiting
Newman Regional Health
Emporia, Kansas, United States
Status: Active, not recruiting
Saint Catherine Hospital
Garden City, Kansas, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Saint Rose Ambulatory and Surgery Center
Great Bend, Kansas, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Hays Medical Center
Hays, Kansas, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Kansas City Cancer Center-West
Kansas City, Kansas, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
University of Kansas Cancer Center
Kansas City, Kansas, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Olathe Medical Center
Olathe, Kansas, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Kansas City Cancer Centers-Southwest
Overland Park, Kansas, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Menorah Medical Center
Overland Park, Kansas, United States
Status: Active, not recruiting
Saint Luke's South Hospital
Overland Park, Kansas, United States
Status: Active, not recruiting
Via Christi Hospital-Pittsburg
Pittsburg, Kansas, United States
Status: Active, not recruiting
Kansas City CCOP
Prairie Village, Kansas, United States
Status: Terminated
Salina Regional Health Center
Salina, Kansas, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Saint Francis Hospital and Medical Center - Topeka
Topeka, Kansas, United States
Status: Active, not recruiting
Cancer Center of Kansas - Main Office
Wichita, Kansas, United States
Status: Recruiting
Contact: Shaker R. Dakhil - 316-262-4467
Oncology Hematology Care Inc-Crestview
Crestview Hills, Kentucky, United States
Status: Active, not recruiting
Hardin Memorial Hospital
Elizabethtown, Kentucky, United States
Status: Active, not recruiting
Baptist Health Lexington
Lexington, Kentucky, United States
Status: Active, not recruiting
Ochsner Health Center-Summa
Baton Rouge, Louisiana, United States
Status: Recruiting
Contact: Jyotsna Fuloria - 888-562-4763
Ochsner Medical Center Jefferson
New Orleans, Louisiana, United States
Status: Recruiting
Contact: Jyotsna Fuloria - 888-562-4763
Bixby Medical Center
Adrian, Michigan, United States
Status: Terminated
Hickman Cancer Center
Adrian, Michigan, United States
Status: Active, not recruiting
Michigan Cancer Research Consortium CCOP
Ann Arbor, Michigan, United States
Status: Terminated
Saint Joseph Mercy Hospital
Ann Arbor, Michigan, United States
Status: Recruiting
Contact: Tareq Al Baghdadi - 734-712-4673
Bronson Battle Creek
Battle Creek, Michigan, United States
Status: Active, not recruiting
Oakwood Hospital and Medical Center
Dearborn, Michigan, United States
Status: Active, not recruiting
Saint John Hospital and Medical Center
Detroit, Michigan, United States
Status: Active, not recruiting
Green Bay Oncology - Escanaba
Escanaba, Michigan, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Genesys Hurley Cancer Institute
Flint, Michigan, United States
Status: Active, not recruiting
Hurley Medical Center
Flint, Michigan, United States
Status: Active, not recruiting
Grand Rapids Clinical Oncology Program
Grand Rapids, Michigan, United States
Status: Terminated
Mercy Health Saint Mary's
Grand Rapids, Michigan, United States
Status: Active, not recruiting
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan, United States
Status: Active, not recruiting
Green Bay Oncology - Iron Mountain
Iron Mountain, Michigan, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Allegiance Health
Jackson, Michigan, United States
Status: Active, not recruiting
Sparrow Hospital
Lansing, Michigan, United States
Status: Active, not recruiting
Saint Mary Mercy Hospital
Livonia, Michigan, United States
Status: Active, not recruiting
Mercy Memorial Hospital
Monroe, Michigan, United States
Status: Terminated
Toledo Clinic Cancer Centers-Monroe
Monroe, Michigan, United States
Status: Active, not recruiting
Mercy Health Mercy Campus
Muskegon, Michigan, United States
Status: Active, not recruiting
Lakeland Community Hospital
Niles, Michigan, United States
Status: Active, not recruiting
Saint Joseph Mercy Oakland
Pontiac, Michigan, United States
Status: Active, not recruiting
Saint Joseph Mercy Port Huron
Port Huron, Michigan, United States
Status: Active, not recruiting
Spectrum Health Reed City Hospital
Reed City, Michigan, United States
Status: Active, not recruiting
Saint Mary's of Michigan
Saginaw, Michigan, United States
Status: Active, not recruiting
Marie Yeager Cancer Center
Saint Joseph, Michigan, United States
Status: Active, not recruiting
Lakeland Hospital
St. Joseph, Michigan, United States
Status: Active, not recruiting
Munson Medical Center
Traverse City, Michigan, United States
Status: Active, not recruiting
Saint John Macomb-Oakland Hospital
Warren, Michigan, United States
Status: Active, not recruiting
Fairview Ridges Hospital
Burnsville, Minnesota, United States
Status: Active, not recruiting
Mercy Hospital
Coon Rapids, Minnesota, United States
Status: Active, not recruiting
Essentia Health Cancer Center
Duluth, Minnesota, United States
Status: Active, not recruiting
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota, United States
Status: Active, not recruiting
Miller-Dwan Hospital
Duluth, Minnesota, United States
Status: Active, not recruiting
Fairview-Southdale Hospital
Edina, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Unity Hospital
Fridley, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Hutchinson Area Health Care
Hutchinson, Minnesota, United States
Status: Active, not recruiting
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, United States
Status: Active, not recruiting
Saint John's Hospital - Healtheast
Maplewood, Minnesota, United States
Status: Active, not recruiting
Abbott-Northwestern Hospital
Minneapolis, Minnesota, United States
Status: Active, not recruiting
Health Partners Inc
Minneapolis, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
Hennepin County Medical Center
Minneapolis, Minnesota, United States
Status: Active, not recruiting
New Ulm Medical Center
New Ulm, Minnesota, United States
Status: Active, not recruiting
North Memorial Medical Health Center
Robbinsdale, Minnesota, United States
Status: Active, not recruiting
Mayo Clinic
Rochester, Minnesota, United States
Status: Recruiting
Contact: Timothy J. Hobday - 507-538-7623
Metro-Minnesota NCI Community Oncology Research Program
Saint Louis Park, Minnesota, United States
Status: Terminated
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, United States
Status: Active, not recruiting
Regions Hospital
Saint Paul, Minnesota, United States
Status: Recruiting
Contact: Daniel M. Anderson - 952-993-1517 - MMCCOP@parknicollet.com
United Hospital
Saint Paul, Minnesota, United States
Status: Active, not recruiting
Saint Francis Regional Medical Center
Shakopee, Minnesota, United States
Status: Active, not recruiting
Lakeview Hospital
Stillwater, Minnesota, United States
Status: Active, not recruiting
Ridgeview Medical Center
Waconia, Minnesota, United States
Status: Active, not recruiting
Rice Memorial Hospital
Willmar, Minnesota, United States
Status: Active, not recruiting
Minnesota Oncology and Hematology PA-Woodbury
Woodbury, Minnesota, United States
Status: Active, not recruiting
CoxHealth Cancer Center
Branson, Missouri, United States
Status: Active, not recruiting
Southeast Cancer Center
Cape Girardeau, Missouri, United States
Status: Active, not recruiting
University of Missouri - Ellis Fischel
Columbia, Missouri, United States
Status: Recruiting
Contact: Clint D. Kingsley - 573-882-7440
Centerpoint Medical Center LLC
Independence, Missouri, United States
Status: Active, not recruiting
Capital Region Medical Center-Goldschmidt Cancer Center
Jefferson City, Missouri, United States
Status: Active, not recruiting
Mercy Hospital-Joplin
Joplin, Missouri, United States
Status: Active, not recruiting
Heartland Hematology and Oncology Associates Incorporated
Kansas City, Missouri, United States
Status: Active, not recruiting
Kansas City Cancer Center - South
Kansas City, Missouri, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Kansas City Cancer Centers - North
Kansas City, Missouri, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Research Medical Center
Kansas City, Missouri, United States
Status: Active, not recruiting
Saint Luke's Hospital of Kansas City
Kansas City, Missouri, United States
Status: Active, not recruiting
Truman Medical Center
Kansas City, Missouri, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Kansas City Cancer Center-Lee's Summit
Lee's Summit, Missouri, United States
Status: Recruiting
Contact: Mazin F. Al-kasspooles - 913-945-7552 - ctnursenav@kumc.edu
Saint Luke's East - Lee's Summit
Lee's Summit, Missouri, United States
Status: Active, not recruiting
Liberty Radiation Oncology Center
Liberty, Missouri, United States
Status: Active, not recruiting
Phelps County Regional Medical Center
Rolla, Missouri, United States
Status: Active, not recruiting
Saint John's Clinic-Rolla-Cancer and Hematology
Rolla, Missouri, United States
Status: Active, not recruiting
Heartland Regional Medical Center
Saint Joseph, Missouri, United States
Status: Active, not recruiting
Mercy Hospital Saint Louis
Saint Louis, Missouri, United States
Status: Active, not recruiting
Missouri Baptist Medical Center
Saint Louis, Missouri, United States
Status: Active, not recruiting
Saint Louis Cancer and Breast Institute-South City
Saint Louis, Missouri, United States
Status: Active, not recruiting
Washington University School of Medicine
Saint Louis, Missouri, United States
Status: Recruiting
Contact: Benjamin R. Tan - 800-600-3606 - info@siteman.wustl.edu
Cancer Research for the Ozarks NCORP
Springfield, Missouri, United States
Status: Terminated
CoxHealth South Hospital
Springfield, Missouri, United States
Status: Active, not recruiting
Mercy Hospital Springfield
Springfield, Missouri, United States
Status: Active, not recruiting
Billings Clinic Cancer Center
Billings, Montana, United States
Status: Active, not recruiting
Montana Cancer Consortium CCOP
Billings, Montana, United States
Status: Active, not recruiting
Saint Vincent Healthcare
Billings, Montana, United States
Status: Active, not recruiting
Bozeman Deaconess Hospital
Bozeman, Montana, United States
Status: Active, not recruiting
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana, United States
Status: Active, not recruiting
Benefis Healthcare- Sletten Cancer Institute
Great Falls, Montana, United States
Status: Active, not recruiting
Saint Peter's Community Hospital
Helena, Montana, United States
Status: Active, not recruiting
Kalispell Regional Medical Center
Kalispell, Montana, United States
Status: Active, not recruiting
Saint Patrick Hospital - Community Hospital
Missoula, Montana, United States
Status: Active, not recruiting
Nebraska Cancer Research Center
Lincoln, Nebraska, United States
Status: Active, not recruiting
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, United States
Status: Active, not recruiting
Alegent Health Immanuel Medical Center
Omaha, Nebraska, United States
Status: Active, not recruiting
Alegent Health Lakeside Hospital
Omaha, Nebraska, United States
Status: Active, not recruiting
Creighton University Medical Center
Omaha, Nebraska, United States
Status: Active, not recruiting
Missouri Valley Cancer Consortium
Omaha, Nebraska, United States
Status: Active, not recruiting
Nebraska Methodist Hospital
Omaha, Nebraska, United States
Status: Active, not recruiting
21st Century Oncology - Henderson
Henderson, Nevada, United States
Status: Active, not recruiting
Cancer and Blood Specialists-Henderson
Henderson, Nevada, United States
Status: Active, not recruiting
Comprehensive Cancer Centers of Nevada - Henderson
Henderson, Nevada, United States
Status: Active, not recruiting
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson, Nevada, United States
Status: Active, not recruiting
Las Vegas Cancer Center-Henderson
Henderson, Nevada, United States
Status: Active, not recruiting
21st Century Oncology
Las Vegas, Nevada, United States
Status: Active, not recruiting
21st Century Oncology - Fort Apache
Las Vegas, Nevada, United States
Status: Active, not recruiting
21st Century Oncology - Vegas Tenaya
Las Vegas, Nevada, United States
Status: Active, not recruiting
Cancer and Blood Specialists-Fort Apache
Las Vegas, Nevada, United States
Status: Active, not recruiting
Cancer and Blood Specialists-Shadow
Las Vegas, Nevada, United States
Status: Active, not recruiting
Cancer and Blood Specialists-Tenaya
Las Vegas, Nevada, United States
Status: Active, not recruiting
Cancer Therapy and Integrative Medicine
Las Vegas, Nevada, United States
Status: Active, not recruiting
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada, United States
Status: Active, not recruiting
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada, United States
Status: Active, not recruiting
Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas, Nevada, United States
Status: Active, not recruiting
Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas, Nevada, United States
Status: Active, not recruiting
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
Las Vegas, Nevada, United States
Status: Active, not recruiting
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
Las Vegas, Nevada, United States
Status: Active, not recruiting
HealthCare Partners Medical Group Oncology/Hematology-San Martin
Las Vegas, Nevada, United States
Status: Active, not recruiting
HealthCare Partners Medical Group Oncology/Hematology-Tenaya
Las Vegas, Nevada, United States
Status: Active, not recruiting
Las Vegas Cancer Center-Medical Center
Las Vegas, Nevada, United States
Status: Active, not recruiting
Nevada Cancer Research Foundation CCOP
Las Vegas, Nevada, United States
Status: Active, not recruiting
Radiation Oncology Centers of Nevada Central
Las Vegas, Nevada, United States
Status: Active, not recruiting
Radiation Oncology Centers of Nevada Southeast
Las Vegas, Nevada, United States
Status: Active, not recruiting
University Medical Center of Southern Nevada
Las Vegas, Nevada, United States
Status: Active, not recruiting
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States
Status: Recruiting
Contact: J. M. Pipas - 800-639-6918 - cancer.research.nurse@dartmouth.edu
Cooper Hospital University Medical Center
Camden, New Jersey, United States
Status: Active, not recruiting
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, United States
Status: Recruiting
Contact: Rebecca A. Moss - 732-235-8675
University of New Mexico
Albuquerque, New Mexico, United States
Status: Active, not recruiting
Memorial Medical Center - Las Cruces
Las Cruces, New Mexico, United States
Status: Active, not recruiting
Montefiore Medical Center - Moses Campus
Bronx, New York, United States
Status: Active, not recruiting
Montefiore Medical Center-Einstein Campus
Bronx, New York, United States
Status: Active, not recruiting
Glens Falls Hospital
Glens Falls, New York, United States
Status: Active, not recruiting
University of Rochester
Rochester, New York, United States
Status: Recruiting
Contact: Jonathan W. Friedberg - 585-275-5830
Syracuse Veterans Administration Medical Center
Syracuse, New York, United States
Status: Active, not recruiting
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
Status: Recruiting
Contact: Stephen A. Bernard - 877-668-0683 - cancerclinicaltrials@med.unc.edu
Wayne Memorial Hospital
Goldsboro, North Carolina, United States
Status: Active, not recruiting
Hendersonville Hematology and Oncology at Pardee
Hendersonville, North Carolina, United States
Status: Active, not recruiting
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina, United States
Status: Recruiting
Contact: James E. Radford - 828-696-4716
Kinston Medical Specialists PA
Kinston, North Carolina, United States
Status: Recruiting
Contact: Peter R. Watson - 252-559-2200
Iredell Memorial Hospital
Statesville, North Carolina, United States
Status: Active, not recruiting
Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota, United States
Status: Active, not recruiting
Strecker Cancer Center-Belpre
Belpre, Ohio, United States
Status: Active, not recruiting
Toledo Clinic Cancer Centers-Bowling Green
Bowling Green, Ohio, United States
Status: Terminated
Adena Regional Medical Center
Chillicothe, Ohio, United States
Status: Active, not recruiting
Oncology Hematology Care Inc - Anderson
Cincinnati, Ohio, United States
Status: Active, not recruiting
Oncology Hematology Care Inc - Kenwood
Cincinnati, Ohio, United States
Status: Active, not recruiting
Oncology Hematology Care Inc-Blue Ash
Cincinnati, Ohio, United States
Status: Active, not recruiting
Oncology Hematology Care Inc-Eden Park
Cincinnati, Ohio, United States
Status: Active, not recruiting
Oncology Hematology Care Inc-Mercy West
Cincinnati, Ohio, United States
Status: Active, not recruiting
Case Western Reserve University
Cleveland, Ohio, United States
Status: Active, not recruiting
Columbus CCOP
Columbus, Ohio, United States
Status: Terminated
Columbus Oncology and Hematology Associates Inc
Columbus, Ohio, United States
Status: Active, not recruiting
Doctors Hospital
Columbus, Ohio, United States
Status: Active, not recruiting
Grant Medical Center
Columbus, Ohio, United States
Status: Active, not recruiting
Mount Carmel Health Center West
Columbus, Ohio, United States
Status: Active, not recruiting
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States
Status: Recruiting
Contact: Manisha H. Shah - 800-293-5066 - Jamesline@osumc.edu
Riverside Methodist Hospital
Columbus, Ohio, United States
Status: Active, not recruiting
The Mark H Zangmeister Center
Columbus, Ohio, United States
Status: Active, not recruiting
Dayton CCOP
Dayton, Ohio, United States
Status: Terminated
Good Samaritan Hospital - Dayton
Dayton, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Miami Valley Hospital
Dayton, Ohio, United States
Status: Active, not recruiting
Samaritan North Health Center
Dayton, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Delaware Health Center-Grady Cancer Center
Delaware, Ohio, United States
Status: Active, not recruiting
Delaware Radiation Oncology
Delaware, Ohio, United States
Status: Active, not recruiting
Grady Memorial Hospital
Delaware, Ohio, United States
Status: Active, not recruiting
Oncology Hematology Care Inc-Healthplex
Fairfield, Ohio, United States
Status: Active, not recruiting
Blanchard Valley Hospital
Findlay, Ohio, United States
Status: Active, not recruiting
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, United States
Status: Active, not recruiting
Wayne Hospital
Greenville, Ohio, United States
Status: Active, not recruiting
Kettering Medical Center
Kettering, Ohio, United States
Status: Active, not recruiting
Fairfield Medical Center
Lancaster, Ohio, United States
Status: Active, not recruiting
Lancaster Radiation Oncology
Lancaster, Ohio, United States
Status: Terminated
Lima Memorial Hospital
Lima, Ohio, United States
Status: Terminated
Marietta Memorial Hospital
Marietta, Ohio, United States
Status: Active, not recruiting
Toledo Clinic Cancer Centers-Maumee
Maumee, Ohio, United States
Status: Active, not recruiting
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Maumee, Ohio, United States
Status: Active, not recruiting
Knox Community Hospital
Mount Vernon, Ohio, United States
Status: Active, not recruiting
Licking Memorial Hospital
Newark, Ohio, United States
Status: Active, not recruiting
Newark Radiation Oncology
Newark, Ohio, United States
Status: Active, not recruiting
Saint Charles Hospital
Oregon, Ohio, United States
Status: Active, not recruiting
Toledo Clinic Cancer Centers-Oregon
Oregon, Ohio, United States
Status: Terminated
Southern Ohio Medical Center
Portsmouth, Ohio, United States
Status: Active, not recruiting
Springfield Regional Medical Center
Springfield, Ohio, United States
Status: Active, not recruiting
Flower Hospital
Sylvania, Ohio, United States
Status: Active, not recruiting
Mercy Hospital of Tiffin
Tiffin, Ohio, United States
Status: Terminated
Mercy Saint Anne Hospital
Toledo, Ohio, United States
Status: Active, not recruiting
Saint Vincent Mercy Medical Center
Toledo, Ohio, United States
Status: Terminated
Toledo Clinic Cancer Centers-Toledo
Toledo, Ohio, United States
Status: Active, not recruiting
Toledo Community Hospital Oncology Program CCOP
Toledo, Ohio, United States
Status: Active, not recruiting
University of Toledo
Toledo, Ohio, United States
Status: Active, not recruiting
Upper Valley Medical Center
Troy, Ohio, United States
Status: Active, not recruiting
Fulton County Health Center
Wauseon, Ohio, United States
Status: Terminated
Saint Ann's Hospital
Westerville, Ohio, United States
Status: Active, not recruiting
Genesis HealthCare System
Zanesville, Ohio, United States
Status: Active, not recruiting
Cancer Centers of Southwest Oklahoma Research
Lawton, Oklahoma, United States
Status: Recruiting
Contact: Nadim F. Nimeh - 877-231-4440
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
Status: Recruiting
Contact: Raid Aljumaily - 405-271-4272 - julie-traylor@ouhsc.edu
Tulsa Cancer Institute
Tulsa, Oklahoma, United States
Status: Recruiting
Contact: Raid Aljumaily - 405-271-4272 - julie-traylor@ouhsc.edu
Clackamas Radiation Oncology Center
Clackamas, Oregon, United States
Status: Active, not recruiting
Providence Milwaukie Hospital
Milwaukie, Oregon, United States
Status: Terminated
Providence Newberg Medical Center
Newberg, Oregon, United States
Status: Recruiting
Contact: Keith S. Lanier - 503-215-6412
Providence Willamette Falls Medical Center
Oregon City, Oregon, United States
Status: Recruiting
Contact: Keith S. Lanier - 503-215-6412
Providence Portland Medical Center
Portland, Oregon, United States
Status: Recruiting
Contact: Keith S. Lanier - 503-215-6412
Providence Saint Vincent Medical Center
Portland, Oregon, United States
Status: Active, not recruiting
Western Oncology Research Consortium
Portland, Oregon, United States
Status: Terminated
Saint Luke's University Hospital-Bethlehem Campus
Bethlehem, Pennsylvania, United States
Status: Recruiting
Contact: Darius C. Desai - infolink@slhn.org
Geisinger Medical Center
Danville, Pennsylvania, United States
Status: Active, not recruiting
Geisinger Medical Center-Cancer Center Hazleton
Hazleton, Pennsylvania, United States
Status: Active, not recruiting
Guthrie Medical Group PC-Robert Packer Hospital
Sayre, Pennsylvania, United States
Status: Active, not recruiting
Geisinger Medical Group
State College, Pennsylvania, United States
Status: Active, not recruiting
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania, United States
Status: Active, not recruiting
Susquehanna Cancer Center
Williamsport, Pennsylvania, United States
Status: Recruiting
Contact: Warren L. Robinson - 800-598-4282
McLeod Regional Medical Center
Florence, South Carolina, United States
Status: Active, not recruiting
Greenville Health System Cancer Institute-Butternut
Greenville, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Eastside
Greenville, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Faris
Greenville, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Memorial Hospital
Greenville, South Carolina, United States
Status: Active, not recruiting
Greenville Health System Cancer Institute-Greer
Greer, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Seneca
Seneca, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Greenville Health System Cancer Institute-Spartanburg
Spartanburg, South Carolina, United States
Status: Recruiting
Contact: Jeffrey K. Giguere - 864-241-6251
Rapid City Regional Hospital
Rapid City, South Dakota, United States
Status: Active, not recruiting
Baylor University Medical Center
Dallas, Texas, United States
Status: Recruiting
Contact: Andrew D. McCollum - 800-422-9567
The Methodist Hospital System
Houston, Texas, United States
Status: Recruiting
Contact: Alexandria T. Phan - 713-790-2700
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States
Status: Recruiting
Contact: Laura L. Tenner - 210-450-3800
American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork, Utah, United States
Status: Active, not recruiting
Sandra L Maxwell Cancer Center
Cedar City, Utah, United States
Status: Active, not recruiting
Logan Regional Hospital
Logan, Utah, United States
Status: Active, not recruiting
Intermountain Medical Center
Murray, Utah, United States
Status: Recruiting
Contact: Mark J. Ott - 801-507-3950
McKay-Dee Hospital Center
Ogden, Utah, United States
Status: Recruiting
Contact: Mark J. Ott - 801-507-3950
Utah Valley Regional Medical Center
Provo, Utah, United States
Status: Active, not recruiting
Dixie Medical Center Regional Cancer Center
Saint George, Utah, United States
Status: Active, not recruiting
LDS Hospital
Salt Lake City, Utah, United States
Status: Active, not recruiting
Utah Cancer Specialists-Salt Lake City
Salt Lake City, Utah, United States
Status: Active, not recruiting
Southwestern Vermont Medical Center
Bennington, Vermont, United States
Status: Recruiting
Contact: J. M. Pipas - 800-639-6918 - cancer.research.nurse@dartmouth.edu
Fredericksburg Oncology Inc
Fredericksburg, Virginia, United States
Status: Terminated
Compass Oncology Vancouver
Vancouver, Washington, United States
Status: Active, not recruiting
PeaceHealth Southwest Medical Center
Vancouver, Washington, United States
Status: Active, not recruiting
Edwards Comprehensive Cancer Center
Huntington, West Virginia, United States
Status: Recruiting
Contact: Maria R. Tria Tirona - 304-399-6617
Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin, United States
Status: Active, not recruiting
Marshfield Clinic Cancer Center at Sacred Heart
Eau Claire, Wisconsin, United States
Status: Recruiting
Contact: Rezwan Islam - 715-393-1400
Sacred Heart Hospital
Eau Claire, Wisconsin, United States
Status: Recruiting
Contact: Rezwan Islam - 715-393-1400
Green Bay Oncology at Saint Vincent Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Green Bay Oncology Limited at Saint Mary's Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Saint Mary's Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Saint Vincent Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States
Status: Recruiting
Contact: Noelle K. LoConte - 877-405-6866
Holy Family Memorial Hospital
Manitowoc, Wisconsin, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Marshfield Clinic
Marshfield, Wisconsin, United States
Status: Recruiting
Contact: Rezwan Islam - 715-393-1400
Saint Joseph's Hospital
Marshfield, Wisconsin, United States
Status: Active, not recruiting
Froedtert and the Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Status: Recruiting
Contact: James P. Thomas - 414-805-4380
Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin, United States
Status: Active, not recruiting
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, United States
Status: Active, not recruiting
Green Bay Oncology - Oconto Falls
Oconto Falls, Wisconsin, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Marshfield Clinic at James Beck Cancer Center
Rhinelander, Wisconsin, United States
Status: Active, not recruiting
Saint Mary's Hospital
Rhinelander, Wisconsin, United States
Status: Active, not recruiting
Marshfield Clinic-Rice Lake Center
Rice Lake, Wisconsin, United States
Status: Recruiting
Contact: Rezwan Islam - 715-393-1400
Saint Nicholas Hospital
Sheboygan, Wisconsin, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Marshfield Clinic Cancer Care at Saint Michael's Hospital
Stevens Point, Wisconsin, United States
Status: Active, not recruiting
Saint Michael's Hospital
Stevens Point, Wisconsin, United States
Status: Active, not recruiting
Green Bay Oncology - Sturgeon Bay
Sturgeon Bay, Wisconsin, United States
Status: Recruiting
Contact: Anthony J. Jaslowski - 800-432-6049
Marshfield Clinic-Wausau Center
Wausau, Wisconsin, United States
Status: Active, not recruiting
Marshfield Clinic - Weston Center
Weston, Wisconsin, United States
Status: Active, not recruiting
Saint Clare's Hospital
Weston, Wisconsin, United States
Status: Active, not recruiting
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin, United States
Status: Active, not recruiting
Rocky Mountain Oncology
Casper, Wyoming, United States
Status: Terminated
Welch Cancer Center
Sheridan, Wyoming, United States
Status: Active, not recruiting
Tom Baker Cancer Centre
Calgary, Alberta, Canada
Status: Recruiting
Contact: Cynthia M. Card - 403-521-3433
BCCA-Vancouver Cancer Centre
Vancouver, British Columbia, Canada
Status: Active, not recruiting
The Vitalite Health Network - Dr Leon Richard Oncology Centre
Moncton, New Brunswick, Canada
Status: Recruiting
Contact: Nicholas G. Finn - 506-862-4005
QEII Health Sciences Centre/Capital District Health Authority
Halifax, Nova Scotia, Canada
Status: Recruiting
Contact: Daniel Rayson - 902-473-6000
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, Canada
Status: Recruiting
Contact: Brandon M. Meyers - 905-387-9495
Ottawa Hospital and Cancer Center-General Campus
Ottawa, Ontario, Canada
Status: Recruiting
Contact: Timothy R. Asmis - 613-761-4395 - info@ohri.ca
University Health Network-Princess Margaret Hospital
Toronto, Ontario, Canada
Status: Recruiting
Contact: Monika K. Krzyzanowska - 416-946-4501 - clinical.trials@uhn.on.ca
CHUM - Hopital Notre-Dame
Montreal, Quebec, Canada
Status: Recruiting
Contact: Francine Aubin - 514-890-8000 - sylvie.beaudoin.chum@ssss.gouv.qc.ca
Allan Blair Cancer Centre
Regina, Saskatchewan, Canada
Status: Recruiting
Contact: Haji I. Chalchal - 306-766-2213
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, Canada
Status: Recruiting
Contact: Sunil K. Yadav - 306-655-2914
Start Date
June 2013
Sponsors
National Cancer Institute (NCI)
Source
National Cancer Institute (NCI)
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page