Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy.
Conditions
Newly Diagnosed - Advanced Ovarian Cancer - FIGO Stage III-IV - BRCA Mutation - Complete Response - Partial Response - First Line Platinum Chemotherapy
Conditions: official terms
Ovarian Neoplasms
Conditions: Keywords
BRCA, Ovarian Cancer, Chemotherapy, PARP inhibitor, First Line, FIGO Stage III, FIGO Stage IV
Study Type
Interventional
Study Phase
Phase 3
Study Design
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Intervention
Name: Olaparib 300mg tablets
Type: Drug
Overall Status
Recruiting
Summary
Olaparib Monotherapy in Patients with BRCA Mutated Ovarian Cancer following First Line Platinum Based Chemotherapy.
Detailed Description
A Phase III, Randomised, Double Blind, Placebo Controlled, Multicentre Study of Olaparib Maintenance Monotherapy in Patients with BRCA Mutated Advanced (FIGO Stage III-IV) Ovarian Cancer following First Line Platinum Based Chemotherapy.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Female
Criteria: Inclusion Criteria:

- Female patients with newly diagnosed, histologically confirmed, high risk advanced (FIGO stage III - IV) BRCA mutated high grade serous or high grade endometrioid ovarian cancer, primary peritoneal cancer and / or fallopian-tube cancer who have completed first line platinum based chemotherapy (intravenous or intraperitoneal).

- Stage III patients must have had one attempt at optimal debulking surgery (upfront or interval debulking). Stage IV patients must have had either a biopsy and/or upfront or interval debulking surgery.

- Documented mutation in BRCA1 or BRCA2 that is predicted to be deleterious or suspected deleterious (known or predicted to be detrimental/lead to loss of function).

- Patients who have completed first line platinum (e.g. carboplatin or cisplatin), containing therapy (intravenous or intraperitoneal) prior to randomisation:

- Patients must have, in the opinion of the investigator, clinical complete response or partial response and have no clinical evidence of disease progression on the post treatment scan or rising CA-125 level, following completion of this chemotherapy course. Patients with stable disease on the post-treatment scan at completion of first line platinum-containing therapy are not eligible for the study.

- Patients must be randomized within 8 weeks of their last dose of chemotherapy

Exclusion Criteria:

- BRCA1 and/or BRCA2 mutations that are considered to be non detrimental (e.g. "Variants of uncertain clinical significance" or "Variant of unknown significance" or "Variant, favor polymorphism" or "benign polymorphism" etc).

- Patients with early stage disease (FIGO Stage I, IIA, IIB or IIC)

- Stable disease or progressive disease on the post-treatment scan or clinical evidence of progression at the end of the patient's first line chemotherapy treatment.

- Patients where more than one debulking surgery has been performed before randomisation to the study. (Patients who, at the time of diagnosis, are deemed to be unresectable and undergo only a biopsy or oophorectomy but then go on to receive chemotherapy and interval debulking surgery are eligible).

- Patients who have previously been diagnosed and treated for earlier stage ovarian, fallopian tube or primary peritoneal cancer.

- Patients who have previously received chemotherapy for any abdominal or pelvic tumour, including treatment for prior diagnosis at an earlier stage for their ovarian, fallopian tube or primary peritoneal cancer. (Patients who have received prior adjuvant chemotherapy for localised breast cancer may be eligible, provided that it was completed more than three years prior to registration, and that the patient remains free of recurrent or metastatic disease).

- Patients with synchronous primary endometrial cancer unless both of the following criteria are met: 1) stage <2 2) less than 60 years old at the time of diagnosis of endometrial cancer with stage IA or IB grade 1 or 2, or stage IA grade 3 endometrioid adenocarcinoma OR ≥ 60 years old at the time of diagnosis of endometrial cancer with Stage IA grade 1 or 2 endometrioid adenocarcinoma. Patients with serous or clear cell adenocarcinoma or carcinosarcoma of the endometrium are not eligible.
Locations
Clearview Cancer Institute
Huntsville, Alabama, United States
Status: Active, not recruiting
Providence Cancer Center
Anchorage, Alaska, United States
Status: Active, not recruiting
St. Joseph's Hospital & Medical Center
Phoenix, Arizona, United States
Status: Active, not recruiting
University of Arizona Cancer Center
Tucson, Arizona, United States
Status: Withdrawn
Cedars-Sinai Medical Center
Los Angeles, California, United States
Status: Active, not recruiting
University of California, Los Angeles
Los Angeles, California, United States
Status: Active, not recruiting
Kaiser Permanente
Oakland, California, United States
Status: Active, not recruiting
Kaiser Permanente
Roseville, California, United States
Status: Active, not recruiting
Kaiser Permanente
Sacramento, California, United States
Status: Withdrawn
Kaiser Permanente Medical Center
San Diego, California, United States
Status: Withdrawn
Kaiser Permanente
San Francisco, California, United States
Status: Withdrawn
Kaiser Permanente
San Jose, California, United States
Status: Withdrawn
Kaiser Permanente
San Leandro, California, United States
Status: Withdrawn
Kaiser Permanente
Santa Carla, California, United States
Status: Withdrawn
Kaiser Permanente
South San Francisco, California, United States
Status: Withdrawn
Stanford Women's Cancer Center
Stanford, California, United States
Status: Active, not recruiting
Babak Edraki
Walnut Creek, California, United States
Status: Active, not recruiting
Kaiser Permanente
Walnut Creek, California, United States
Status: Withdrawn
University of Colorado
Aurora, Colorado, United States
Status: Active, not recruiting
Univ of Connecticut Health Center
Farmington, Connecticut, United States
Status: Terminated
Hartford Hospital
Hartford, Connecticut, United States
Status: Withdrawn
The Hospital of Central Connecticut
New Britain, Connecticut, United States
Status: Withdrawn
Smilow Cancer Hospital at Yale New Haven
New Haven, Connecticut, United States
Status: Active, not recruiting
Christiana Care Health Services
Newark, Delaware, United States
Status: Withdrawn
Florida Hospital Cancer Institute
Orlando, Florida, United States
Status: Active, not recruiting
Gynecologic Cancer Center
Orlando, Florida, United States
Status: Active, not recruiting
H Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, United States
Status: Active, not recruiting
Northside Hospital
Atlanta, Georgia, United States
Status: Active, not recruiting
Georgia Regents University
Augusta, Georgia, United States
Status: Withdrawn
Northeast Georgia Medical Center
Gainesville, Georgia, United States
Status: Terminated
Nancy N. & J.C. Lewis Cancer and Research Pavillion
Savannah, Georgia, United States
Status: Terminated
The Queen's Medical Center
Honolulu, Hawaii, United States
Status: Active, not recruiting
University of Hawaii
Honolulu, Hawaii, United States
Status: Active, not recruiting
Northwestern University
Chicago, Illinois, United States
Status: Active, not recruiting
Univ Chicago Medical Center
Chicago, Illinois, United States
Status: Active, not recruiting
Advocate Lutheran General Hospital
Park Ridge, Illinois, United States
Status: Active, not recruiting
Indiana University
Indianapolis, Indiana, United States
Status: Active, not recruiting
St. Vincent Hospital & Health Care Center
Indianapolis, Indiana, United States
Status: Active, not recruiting
Northern Indiana Cancer Research Consortium
Mishawaka, Indiana, United States
Status: Terminated
Community Hospital
Munster, Indiana, United States
Status: Withdrawn
McFarland Clinic, P.C.
Ames, Iowa, United States
Status: Withdrawn
University of Iowa
Iowa City, Iowa, United States
Status: Withdrawn
University of Kansas
Westwood, Kansas, United States
Status: Withdrawn
Norton Cancer Institute Research
Louisville, Kentucky, United States
Status: Terminated
Maine Medical Partners
Scarborough, Maine, United States
Status: Active, not recruiting
Greater Baltimore Medical Center
Baltimore, Maryland, United States
Status: Terminated
Johns Hopkins
Baltimore, Maryland, United States
Status: Active, not recruiting
Sinai Hospital of Baltimore
Baltimore, Maryland, United States
Status: Withdrawn
Walter Reed National Military Medical Center
Bethesda, Maryland, United States
Status: Terminated
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Status: Active, not recruiting
Dana Farber Cancer Institute
Boston, Massachusetts, United States
Status: Active, not recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
Status: Active, not recruiting
University of Masssachusetts Memorial Medical Center
Worcester, Massachusetts, United States
Status: Withdrawn
Henry Ford Health System
Detroit, Michigan, United States
Status: Terminated
Gynecologic Oncology of West MI, PLLC
Grand Rapids, Michigan, United States
Status: Active, not recruiting
Minnesota Oncology Hematology, PA
Edina, Minnesota, United States
Status: Active, not recruiting
Mayo Clinic - Rochester, MN
Rochester, Minnesota, United States
Status: Active, not recruiting
University of Mississippi Medical Center
Jackson, Mississippi, United States
Status: Terminated
Ferrell Duncan Clinic
Springfield, Missouri, United States
Status: Withdrawn
Mercy Clinic Women's Oncology Springfield
Springfield, Missouri, United States
Status: Withdrawn
Washington University School of Medicine
St. Louis, Missouri, United States
Status: Active, not recruiting
Missouri Valley Cancer Consortium CCOP
Omaha, Nebraska, United States
Status: Active, not recruiting
Nebraska Methodist Hospital
Omaha, Nebraska, United States
Status: Active, not recruiting
Womens Cancer Center of Nevada
Las Vegas, Nevada, United States
Status: Active, not recruiting
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States
Status: Withdrawn
MD Anderson at Cooper Cancer Center
Camden, New Jersey, United States
Status: Terminated
John Theurer Cancer Center
Hackensack, New Jersey, United States
Status: Active, not recruiting
Morristown Medical Center
Morristown, New Jersey, United States
Status: Withdrawn
MD Anderson at Cooper Cancer Center
Voorhees, New Jersey, United States
Status: Withdrawn
University of New Mexico
Albuquerque, New Mexico, United States
Status: Active, not recruiting
Women's Cancer Care Associates
Albany, New York, United States
Status: Active, not recruiting
Roswell Park Cancer Institute
Buffalo, New York, United States
Status: Terminated
Memorial Sloan Kettering Cancer Center
New York, New York, United States
Status: Active, not recruiting
Mount Sinai Medical Center - New York
New York, New York, United States
Status: Active, not recruiting
Perlmutter Cancer Center
New York, New York, United States
Status: Terminated
Hope Women's Cancer Centers
Asheville, North Carolina, United States
Status: Active, not recruiting
UNC Chapel Hill
Chapel Hill, North Carolina, United States
Status: Terminated
Levine Cancer Institute
Charlotte, North Carolina, United States
Status: Active, not recruiting
Duke University Medical Center
Durham, North Carolina, United States
Status: Terminated
Sanford Roger Maris Cancer Center
Fargo, North Dakota, United States
Status: Terminated
Summa Health System
Arkron, Ohio, United States
Status: Withdrawn
Aultman Hospital
Canton, Ohio, United States
Status: Terminated
University of Cincinnati
Cincinnati, Ohio, United States
Status: Withdrawn
Cleveland Clinic Foundation
Cleveland,, Ohio, United States
Status: Active, not recruiting
Cleveland Clinic Cancer Center at Fairview Hospital
Cleveland, Ohio, United States
Status: Terminated
University Hospital Case Medical Center
Cleveland, Ohio, United States
Status: Terminated
The Ohio State University Wexner Medical Center
Columbus, Ohio, United States
Status: Active, not recruiting
Kettering Medical Center
Kettering, Ohio, United States
Status: Active, not recruiting
Hillcrest Hospital Cancer Center
Mayfield Hights, Ohio, United States
Status: Terminated
Peggy and Charles Stephenson Cancer Center
Oklahoma City, Oklahoma, United States
Status: Active, not recruiting
Abington Memorial Hospital
Abington, Pennsylvania, United States
Status: Active, not recruiting
St. Luke's University Health Network
Bethlehem, Pennsylvania, United States
Status: Active, not recruiting
The University of Pennsylvania
Philadelphia, Pennsylvania, United States
Status: Active, not recruiting
Women and Infants Hospital
Providence, Rhode Island, United States
Status: Active, not recruiting
South Carolina Oncology Associates, PA
Columbia, South Carolina, United States
Status: Terminated
Upstate Carolina CCOP
Spartanburg, South Carolina, United States
Status: Withdrawn
Sanford Clinic Women's Health
Sioux Falls, South Dakota, United States
Status: Withdrawn
Avera Cancer Institute
Siouxfalls, South Dakota, United States
Status: Active, not recruiting
University of Texas Southwestern Medical Center
Dallas, Texas, United States
Status: Terminated
The University of Texas Medical Branch
Galveston, Texas, United States
Status: Withdrawn
MD Anderson Cancer Center
Houston, Texas, United States
Status: Terminated
University of Texas Health Science Center of Houston
Houston, Texas, United States
Status: Active, not recruiting
Fletcher Allen Health Care
Burlington, Vermont, United States
Status: Withdrawn
University of Virginia
Charlottesville, Virginia, United States
Status: Terminated
Virginia Oncology Associates
Norfolk, Virginia, United States
Status: Terminated
VCU Massey Cancer Center
Richmond, Virginia, United States
Status: Withdrawn
Carilion Clinic Gynecological Oncology
Roanoke, Virginia, United States
Status: Active, not recruiting
University of Washington
Seattle, Washington, United States
Status: Withdrawn
Aurora Baycare Medical Center
Green Bay, Wisconsin, United States
Status: Terminated
University of Wisconsin-Madison
Madison, Wisconsin, United States
Status: Terminated
Aurora St. Luke's Medical Center
Milwaukee, Wisconsin, United States
Status: Withdrawn
Froedtert Memorial Hospital
Milwaukee, Wisconsin, United States
Status: Active, not recruiting
Aurora West Allis Medical Center
West Allis, Wisconsin, United States
Status: Withdrawn
Mercy Hospital for Women
Heidelberg, Australia
Status: Active, not recruiting
The Royal Womens Hospital
Parkville, Australia
Status: Active, not recruiting
Prince of Wales Hospital
Randwick, Australia
Status: Active, not recruiting
Centro Diagnóstico Barretos
Barretos, Brazil
Status: Terminated
Hospital Araujo Jorge
Goiânia, Brazil
Status: Terminated
Centro de Novos Tratamentos Itajai
Itajai, Brazil
Status: Terminated
Hospital de Clinicas de Porto Alegre
Porto Alegre, Brazil
Status: Terminated
Irmandade da Santa Casa de Misericordia de Porto Alagre
Porto Alegre, Brazil
Status: Terminated
Hospital de Base São José do Rio Preto
São José do Rio Preto, Brazil
Status: Terminated
Centro de Referencia da Saude da Mulher
São Paulo, Brazil
Status: Active, not recruiting
Instituto do Câncer de São Paulo
São Paulo, Brazil
Status: Terminated
Juravinski Cancer Centre
Hamilton, Ontario, Canada
Status: Active, not recruiting
London Health Sciences Centre
London, Ontario, Canada
Status: Active, not recruiting
Princess Margaret Cancer Centre
Toronto, Ontario, Canada
Status: Active, not recruiting
Sunnybrook Health Sciences Center
Toronto, Ontario, Canada
Status: Active, not recruiting
CHUM - Hopital Norte-Dame
Montreal, Quebec, Canada
Status: Active, not recruiting
Royal Victoria Hospital
Montreal, Quebec, Canada
Status: Active, not recruiting
Hotel-Dieu de Quebec
Quebec, Canada
Status: Active, not recruiting
Beijing Cancer Hospital
Beijing, China
Status: Recruiting
People's Hospital of Peking University
Beijing, China
Status: Not yet recruiting
The Tumor Hospital affiliated to China Medical Science Insti
Beijing, China
Status: Recruiting
1st Hospital of Jilin university
Changchun, China
Status: Recruiting
Jilin Provincial Cancer Hospital
Changchun, China
Status: Recruiting
Hunan Cancer Hospital
Changsha, China
Status: Recruiting
West China Hospital Affiliated to Sichuan University
Chengdu, China
Status: Recruiting
ChongQing Cancer Hospital
Chongqing, China
Status: Recruiting
Fujian general hospital of Nanjing Military Command
Fuzhou, China
Status: Withdrawn
Cancer Center of SunYet-sen University
Guangzhou, China
Status: Recruiting
Women's Hospital, Zhejaing University School of Medicine
Hangzhou, China
Status: Recruiting
The Tumour Hospital of Harbin Medical University
Harbin, China
Status: Recruiting
Zhejiang Cancer Hospital, Huangzhou
Huangzhou, China
Status: Recruiting
JINAN, Qi Lu Hosp. of SD Univ.
Ji Nan, China
Status: Recruiting
JiangSu Cancer Hospital
Nanjing, China
Status: Withdrawn
Affiliated tumor hospital to Guangxi medical university
Nanning, China
Status: Withdrawn
Obstetris and Gynecology Hospital of Fudan University
Shanghai, China
Status: Recruiting
Shanghai Cancer Hospital of Fudan University
Shanghai, China
Status: Recruiting
The First Affiliated Hospital of Soochow Universit
Suzhou, China
Status: Recruiting
First affiliated hospital college of XianJiaotong University
Xian, China
Status: Recruiting
Institut Bergonie
Bordeaux, France
Status: Active, not recruiting
CAC François Baclesse
Caen Cedex, France
Status: Active, not recruiting
69LYON, C Bérard, Onco
Lyon Cedex 08, France
Status: Terminated
Centre Catherine de Sienne
Nantes,, France
Status: Active, not recruiting
Institut Curie Paris Et Saint Cloud
Paris Cedex 5, France
Status: Withdrawn
75PARIS, H Tenon, Onco
Paris, France
Status: Active, not recruiting
Hopital Européen Georges Pompidou
Paris, France
Status: Withdrawn
69PIERREBE, CH Lyon Sud,
Pierre Benite Cedex, France
Status: Withdrawn
92STCLOUD, C Huguenin, Onco
Saint Cloud, France
Status: Withdrawn
Institut Claudius Regaud
Toulouse, France
Status: Withdrawn
Centre Alexis Vautrin
Vandoeuvre Les Nancy, France
Status: Active, not recruiting
Institut Gustave Roussy
Villejuif Cedex, France
Status: Active, not recruiting
Rambam Health Care Campus
Haifa, Israel
Status: Active, not recruiting
Sapir Medical Centre
Kfar Saba, Israel
Status: Active, not recruiting
Rabin MC
Petach Tikva, Israel
Status: Active, not recruiting
Chaim Sheba Medical Centre
Tel Hashomer, Israel
Status: Active, not recruiting
Tel-Aviv Sourkasy Medical Center
Tel-Aviv, Israel
Status: Terminated
Bari- Istituto Tumori Giovanni Paolo II
Bari, Italy
Status: Terminated
Azienda Ospedaliera "Cannizzaro"
Catania, Italy
Status: Terminated
Istituto Europeo di Oncologia
Milano, Italy
Status: Active, not recruiting
Istituto Nazionale Per Cura Tumori - Milano
Milano, Italy
Status: Active, not recruiting
Istituto Nazionale Tumori Fondazione Pascale
Napoli, Italy
Status: Active, not recruiting
Istituto Oncologico Veneto Irccs
Padova, Italy
Status: Active, not recruiting
Istituto Regina Elena-Polo Oncologico Ifo
Roma, Italy
Status: Active, not recruiting
Policlinico Universitario A. Gemelli
Roma, Italy
Status: Active, not recruiting
Hyogo Cancer Center
Akashi-shi, Japan
Status: Active, not recruiting
National Cancer Center Hospital
Chuo-ku, Japan
Status: Active, not recruiting
National Hospital Organization Kyushu Cancer Center
Fukuoka, Japan
Status: Active, not recruiting
Saitama Medical University International Medical Center
Hidaka-shi, Japan
Status: Active, not recruiting
National Hospital Organisation Shikoku Cancer Center
Matsuyama-shi, Japan
Status: Active, not recruiting
Jikei University Hospital
Minato-ku, Japan
Status: Withdrawn
Niigata University Medical and Dental Hospital
Niigata-shi, Japan
Status: Terminated
Kinki University Hospital
Osaka, Japan
Status: Withdrawn
Hokkaido University
Sapporo-shi, Japan
Status: Active, not recruiting
Shizuoka Cancer Center
Sunto-gun, Japan
Status: Active, not recruiting
National Cancer Center
Goyang-si, Korea, Republic of
Status: Active, not recruiting
Asan Medical Center
Seoul, Korea, Republic of
Status: Active, not recruiting
Gangnam Severance Hospital
Seoul, Korea, Republic of
Status: Active, not recruiting
Korea Cancer Center Hospital
Seoul, Korea, Republic of
Status: Active, not recruiting
Samsung Medical Center
Seoul, Korea, Republic of
Status: Active, not recruiting
Seoul National University Hospital
Seoul, Korea, Republic of
Status: Active, not recruiting
Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital
Amsterdam, Netherlands
Status: Active, not recruiting
Leids Universitair Medisch Centrum
Leiden, Netherlands
Status: Withdrawn
Maastricht Universitair Medisch Centrum
Maastricht, Netherlands
Status: Terminated
Niepubliczny Zaklad Opieki Zdrowotnej Innowacyjna Medycyna
Grzepnica, Poland
Status: Active, not recruiting
SPZOZ MSWiA z Warminsko-Mazurskim Centrum Onkologii
Olsztyn, Poland
Status: Active, not recruiting
Wojewódzki Szpital Specjalistyczny w Olsztynie
Olsztyn, Poland
Status: Active, not recruiting
Centrum Onkologii-Instytut im. Marii Sklodowskiej-Curie
Warszawa, Poland
Status: Active, not recruiting
Szpital Specjalistyczny im. Swietej Rodziny SPZOZ
Warszawa, Poland
Status: Terminated
Udmurtia Republic Clinical Oncology Center
Izhevsk, Russian Federation
Status: Terminated
Chemotherapy Department, Russian Cancer Research Centre
Moscow, Russian Federation
Status: Active, not recruiting
State Institution of Heath Omsk Regional Oncology Dispensary
Omsk, Russian Federation
Status: Active, not recruiting
Cancer Research Institute
Saint Petersburg, Russian Federation
Status: Terminated
St.Petersburg City Oncology Dispensary, Dept. Gynecology
Saint Petersburg, Russian Federation
Status: Active, not recruiting
Clinical Research Center specialized types of medical care
St. Petersburg, Russian Federation
Status: Withdrawn
Leningrad Regional Oncology Dispensary
St.Petersburg, Russian Federation
Status: Active, not recruiting
Research Institute of Oncology RAMS
Tomsk, Russian Federation
Status: Terminated
Barcelona,H.Vall d´Hebrón,Oncología
Barcelona, Spain
Status: Active, not recruiting
Córdoba,H.Reina Sofía,Oncología
Córdoba, Spain
Status: Active, not recruiting
H.Llobregat,ICO-Duran i Reynals,Oncología
Hospitalet deLlobregat(Barcelo, Spain
Status: Active, not recruiting
Madrid, MD Anderson, Oncología
Madrid, Spain
Status: Active, not recruiting
Madrid,H.U.La Paz,Oncología
Madrid, Spain
Status: Active, not recruiting
Valencia, IVO, Oncología
Valencia, Spain
Status: Active, not recruiting
Valencia,H.C.U.Valencia,Oncología
Valencia, Spain
Status: Active, not recruiting
City Hospital, Birmingham, Cancer Trials Team
Birmingham, United Kingdom
Status: Terminated
Addenbrooke's Hospital
Cambridge, United Kingdom
Status: Active, not recruiting
Arden Cancer Centre
Coventry, United Kingdom
Status: Active, not recruiting
Edinburgh Cancer Research UK Centre
Edinburgh, United Kingdom
Status: Active, not recruiting
Cancer Research UK and UCL Cancer Trials Centre
London, United Kingdom
Status: Active, not recruiting
Royal Marsden Hospital
London, United Kingdom
Status: Active, not recruiting
Oxford Radcliffe Hospital NHS Trust, Churchill Hospital
Oxford, United Kingdom
Status: Withdrawn
Royal Marsden Hospital and Institute of Cancer Research
Sutton, United Kingdom
Status: Active, not recruiting
Start Date
August 2013
Completion Date
January 2022
Sponsors
AstraZeneca
Source
AstraZeneca
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page