CT in Diagnosing Patients With Lung Cancer
Conditions
Lung Cancer
Conditions: official terms
Lung Neoplasms
Study Type
Interventional
Study Phase
N/A
Study Design
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Intervention
Name: computed tomography Type: Procedure
Name: 4-dimensional computed tomography Type: Procedure
Name: computed tomography Type: Procedure
Name: cone-beam computed tomography Type: Procedure
Name: cone-beam computed tomography Type: Procedure
Overall Status
Recruiting
Summary
This clinical trial studies computed tomography (CT) in diagnosing patients with lung cancer. Diagnostic procedures, such as CT, may help find and diagnose lung cancer.
Detailed Description
PRIMARY OBJECTIVES:

I. Conduct a prospective clinical imaging study to quantify the amount of inter- and intra-physician contouring variability on four dimensional (4D) CT, active breathing control (ABC) CT, free breathing CT, and free breathing and ABC cone beam (CB)CT.

II. Quantify the magnitude and distribution of target and organ at risk volume variations between the different imaging modalities.

III. Determine dosimetric changes related to contouring variations for tumor and normal tissue.

OUTLINE:

Patients undergo conventional free breathing CT, 4D CT, ABC CT, ABC CBCT, and free breathing CBCT before undergoing radiation therapy.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Measurable disease on CT scan

- Patients with lung cancer visible on CT who are scheduled to receive external beam radiation treatment will be eligible for this study

- Patients must be able to perform ABC procedures

Exclusion Criteria:

- Patients requiring continuous supplemental oxygen due to the requirement of spirometry during all imaging studies

- No vulnerable populations will be enrolled (prisoners, children, pregnant females or institutionalized individuals)

- Women of childbearing potential will undergo a pregnancy test
Location
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, United States
Status: Recruiting
Contact: Elisabeth Weiss, MD - 804-828-9463 - eweiss@mcvh-vcu.edu
Start Date
May 2013
Completion Date
February 2016
Sponsors
Virginia Commonwealth University
Source
Virginia Commonwealth University
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page