Suitability of DCE-MRI for Detection of Vascular Changes After VBT
Conditions
Carcinoma of the Cervix, Carcinoma or Carcinosarcoma of the Uterus
Conditions: official terms
Carcinosarcoma - Mixed Tumor, Mullerian - Uterine Cervical Neoplasms - Uterine Neoplasms
Study Type
Interventional
Study Phase
Phase 1
Study Design
Intervention Model: Single Group Assignment, Primary Purpose: Diagnostic
Intervention
Name: Radiotherapy
Type: Radiation
Overall Status
Recruiting
Summary
This is a pilot study of DCE MR imaging to detect vascular changes in the vagina during and after radiotherapy n patients receiving adjuvant brachytherapyfor cervical or endometrial cancer.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Female
Criteria: Inclusion Criteria:

- Must be 18 years of age.

- Must have histologically confirmed carcinoma of the cervix, carcinoma or carcinosarcoma of the uterus.

- Subjects are receiving intracavitary brachytherapy.

- ECOG performance status of 0-2.

- Creatinine clearance 30.

Exclusion Criteria:

- Subjects with an inability to tolerate MR imaging (i.e. claustrphobia)

- Study subjects who have contraindication to MRI scanning such as but not limited to subjects with pacemakers, metal fragments in the eye or certain metallic implants.

- Patients who do not speak or read English.
Location
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Status: Recruiting
Contact: Lilie Lin, MD - 855-216-0098 - PennCancerTrials@emergingmed.com
Start Date
October 2013
Completion Date
October 2016
Sponsors
Abramson Cancer Center of the University of Pennsylvania
Source
Abramson Cancer Center of the University of Pennsylvania
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page