Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer
Conditions
Endometrial Adenocarcinoma - Endometrial Clear Cell Adenocarcinoma - Endometrial Serous Adenocarcinoma - Endometrial Undifferentiated Carcinoma - Recurrent Uterine Corpus Carcinoma - Stage IIIA Uterine Corpus Cancer - Stage IIIB Uterine Corpus Cancer - Stage IIIC Uterine Corpus Cancer - Stage IVA Uterine Corpus Cancer - Stage IVB Uterine Corpus Cancer
Conditions: official terms
Adenocarcinoma - Adenocarcinoma, Clear Cell - Carcinoma - Cystadenocarcinoma, Serous - Uterine Neoplasms
Study Type
Interventional
Study Phase
Phase 2/Phase 3
Study Design
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Intervention
Name: Carboplatin Type: Drug
Name: Laboratory Biomarker Analysis Type: Other
Name: Metformin Hydrochloride Type: Drug
Name: Paclitaxel Type: Drug
Name: Placebo Type: Other
Name: Quality-of-Life Assessment Type: Other
Name: Questionnaire Administration Type: Other
Overall Status
Recruiting
Summary
This randomized phase II/III trial studies how well paclitaxel, carboplatin, and metformin hydrochloride works and compares it to paclitaxel, carboplatin, and placebo in treating patients with endometrial cancer that is stage III, IV, or has come back. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Metformin hydrochloride may help paclitaxel and carboplatin work better by making cancer cells more sensitive to the drugs. It is not yet known whether paclitaxel and carboplatin is more effective with or without metformin hydrochloride in treating endometrial cancer.
Detailed Description
PRIMARY OBJECTIVES:

I. To determine if the addition of metformin (metformin hydrochloride) to the standard regimen of carboplatin and paclitaxel prolongs progression-free survival (PFS) in women with advanced or recurrent endometrial cancer. (Phase II) II. To determine if the addition of metformin to the standard regimen of carboplatin and paclitaxel prolongs overall survival (OS) in the same population if a phase III study is conducted. Both clinical trials (Phase II and III) will utilize OS as a primary endpoint if a phase III trial is opened.

SECONDARY OBJECTIVES:

I. To estimate the proportion of patients with objective response (response rate [RR]) in the population of patients with measurable disease by treatment.

II. To estimate the duration of response in the population of patients with measurable disease who respond by treatment.

III. To estimate overall survival (OS) and relative hazards of death for each treatment arm if the study stops after the phase II trial is completed. If the study continues with a phase III clinical trial, then PFS will be a secondary endpoint.

IV. To determine the nature, frequency and degree of toxicity as assessed by Common Terminology Criteria for Adverse Events (CTCAE) for each treatment arm.

V. To estimate possible differences in RR, PFS, OS, and toxicity rates for the treatment regimens by the patients' level of obesity.

TERTIARY OBJECTIVES:

I. To explore the association of metabolic factors (i.e. body mass index [BMI], hip-to-waist ratio, diabetes status, hemoglobin A1c [HgbA1C], fasting insulin and glucose levels, homeostatic model assessment [HOMA] scores) with treatment response to metformin/paclitaxel/carboplatin.

II. To correlate expression of the metformin transporter proteins (i.e., organic cation transporters [OCT] 1-3, multidrug and toxin extrusion [MATE] 1/2 and plasma membrane monoamine transporter [PMAT]) and key targets of the metformin/mammalian target of rapamycin (mTOR) signaling pathway with treatment response to metformin/paclitaxel/carboplatin.

III. To estimate differences in physical functioning, physical activity, and fatigue between treatment arms.

IV. To explore the association between metabolic factors (i.e., BMI, hip-to-waist ratio, diabetes status, HgbA1C, fasting insulin and glucose levels, HOMA scores) and physical functioning, physical activity, and fatigue.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive paclitaxel intravenously (IV) over 3 hours on day 1, carboplatin IV over 30 minutes on day 1, and metformin hydrochloride orally (PO) twice daily (BID) (approximately 10-12 hours apart ) on days 1-21 (once daily [QD] in course 1). Treatment repeats every 21 days for 6 courses in the absence of disease progression or unacceptable toxicity. Patients then receive maintenance therapy comprising metformin hydrochloride PO BID on days 1-21. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive paclitaxel IV and carboplatin IV as in Arm I. Patients also receive placebo PO BID (approximately 10-12 hours apart) on days 1-21 (QD in course 1). Treatment repeats every 21 days for 6 courses in the absence of disease progression or unacceptable toxicity. Patients then receive maintenance therapy comprising placebo PO BID on days 1-21. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

In both arms, patients who achieve stable disease (SD) or partial response (PR) and still have measurable disease at the completion of course 6 may continue to receive paclitaxel IV and carboplatin IV (with metformin hydrochloride or placebo) for an additional 4 courses at the discretion of the treating investigator.

After completion of study treatment, patients are followed up every 3 months for 2 years and then every 6 months for 3 years.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Female
Criteria: Inclusion Criteria:

- Patients must have measurable stage III, measurable stage IVA, stage IVB (with or without measurable disease) or recurrent (with or without measurable disease) endometrial carcinoma

- Histologic confirmation of the original primary tumor is required; patients with the following histologic epithelial cell types are eligible:

- Endometrioid adenocarcinoma, serous adenocarcinoma, undifferentiated carcinoma, clear cell adenocarcinoma, mixed epithelial carcinoma, adenocarcinoma not otherwise specified (N.O.S.)

- Measurable disease is defined by Response Evaluation Criteria in Solid Tumors (RECIST) (version 1.1); measurable disease is defined as at least one lesion that can be accurately measured in at least one dimension (longest diameter to be recorded); each lesion must be >= 10 mm when measured by computed tomography (CT), magnetic resonance imaging (MRI) or caliper measurement by clinical exam; or >= 20 mm when measured by chest x-ray; lymph nodes must be >= 15 mm in short axis when measured by CT or MRI

- Patients must have a Gynecologic Oncology Group (GOG) performance status of 0, 1, or 2

- Absolute neutrophil count (ANC) greater than or equal to 1,500/mcl

- Platelets greater than or equal to 100,000/mcl

- Creatinine less than 1.4 mg/dl

- Bilirubin less than or equal to 1.5 x institutional/laboratory upper limit of normal (ULN)

- Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) less than or equal to 3 x ULN

- Alkaline phosphatase less than or equal to 2.5 x ULN

- Patients must NOT have received prior chemotherapy or targeted therapy, including chemotherapy used for radiation sensitization for treatment of endometrial carcinoma

- Patients may have received prior radiation therapy for treatment of endometrial carcinoma; prior radiation therapy may have included pelvic radiation therapy, extended field pelvic/para-aortic radiation therapy, and/or intravaginal brachytherapy; all radiation therapy must be completed at least 4 weeks prior to the first date of study therapy

- Patients may have received prior hormonal therapy for treatment of endometrial carcinoma; all hormonal therapy must be discontinued at least one week prior to the first date of study therapy

- Patients must be able to swallow and retain orally-administered medication

- Patients must have signed an approved informed consent and authorization permitting release of personal health information; individuals with impaired decision-making capacity are not eligible to participate on the study

Exclusion Criteria:

- Patients must NOT be taking metformin or have been on metformin in the past 6 months

- Patients with a history of other invasive malignancies, with the exception of non-melanoma skin cancer are excluded if there is any evidence of other malignancy being present within the last three years

- Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements

- Patients who are pregnant or nursing; if patients are of reproductive age and have not undergone hysterectomy, they must use an effective contraceptive method for the duration of this study

- Any condition associated with increased risk of metformin-associated lactic acidosis; (e.g. congestive heart failure defined as New York Heart Association [NYHA] class III or IV functional status, history of acidosis of any type; habitual intake of 3 or more alcoholic beverages per day)
Locations
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States
Status: Recruiting
Contact: Warner K. Huh - 205-934-0309
Tennessee Valley Gynecologic Oncology
Huntsville, Alabama, United States
Status: Recruiting
Contact: David B. Engle - 256-533-6233
Arizona Oncology Associates-Biltmore Cancer Center
Phoenix, Arizona, United States
Status: Active, not recruiting
Saint Joseph's Hospital and Medical Center
Phoenix, Arizona, United States
Status: Recruiting
Contact: John H. Farley - 301-319-2100
Arizona Oncology Associates-West Orange Grove
Tucson, Arizona, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Arizona Oncology Associates-Wilmot
Tucson, Arizona, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
The University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States
Status: Recruiting
Contact: Setsuko K. Chambers - 520-626-9008
The University of Arizona Medical Center-University Campus
Tucson, Arizona, United States
Status: Recruiting
Contact: Setsuko K. Chambers - 520-626-9008
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Status: Recruiting
Contact: Kristin K. Zorn - 501-686-8274
John Muir Medical Center-Concord Campus
Concord, California, United States
Status: Recruiting
Contact: Babak Edraki - 925-674-2580
UC San Diego Moores Cancer Center
La Jolla, California, United States
Status: Recruiting
Contact: Michael T. McHale - 858-822-5354 - cancercto@ucsd.edu
Cedars-Sinai Medical Center
Los Angeles, California, United States
Status: Withdrawn
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States
Status: Recruiting
Contact: Scott E. Lentz - 626-564-3455
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States
Status: Recruiting
Contact: Robin Farias-Eisner - 888-798-0719
Palo Alto Medical Foundation-Gynecologic Oncology
Mountain View, California, United States
Status: Recruiting
Contact: John K. Chan - 415-209-2686 - bernicl@sutterhealth.org
Kaiser Permanente-Oakland
Oakland, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
Saint Joseph Hospital - Orange
Orange, California, United States
Status: Recruiting
Contact: Leslie M. Randall - 714-734-6220
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, United States
Status: Recruiting
Contact: Krishnansu S. Tewari - 714-456-6191 - awallick@uci.edu
Palo Alto Medical Foundation Health Care
Palo Alto, California, United States
Status: Recruiting
Contact: John K. Chan - 415-209-2686 - bernicl@sutterhealth.org
Stanford Cancer Institute
Palo Alto, California, United States
Status: Recruiting
Contact: Oliver Dorigo - 650-498-7061 - ccto-office@stanford.edu
Kaiser Permanente-Roseville
Roseville, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
Kaiser Permanente - Sacramento
Sacramento, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Status: Recruiting
Contact: Edwin A. Alvarez - 916-734-3089
California Pacific Medical Center-Pacific Campus
San Francisco, California, United States
Status: Recruiting
Contact: John K. Chan - 415-209-2686 - bernicl@sutterhealth.org
Kaiser Permanente-San Francisco
San Francisco, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
San Francisco General Hospital
San Francisco, California, United States
Status: Recruiting
Contact: Rebecca A. Brooks - 877-827-3222
UCSF Medical Center-Mission Bay
San Francisco, California, United States
Status: Recruiting
Contact: Rebecca A. Brooks - 877-827-3222
UCSF Medical Center-Mount Zion
San Francisco, California, United States
Status: Recruiting
Contact: Rebecca A. Brooks - 877-827-3222
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
Kaiser Permanente San Leandro
San Leandro, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California, United States
Status: Recruiting
Contact: John K. Chan - 415-209-2686 - bernicl@sutterhealth.org
Kaiser Permanente-South San Francisco
South San Francisco, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
Palo Atlo Medical Foundation-Sunnyvale
Sunnyvale, California, United States
Status: Recruiting
Contact: John K. Chan - 415-209-2686 - bernicl@sutterhealth.org
Olive View-University of California Los Angeles Medical Center
Sylmar, California, United States
Status: Active, not recruiting
Kaiser Permanente-Vallejo
Vallejo, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
John Muir Medical Center-Walnut Creek
Walnut Creek, California, United States
Status: Recruiting
Contact: Babak Edraki - 925-674-2580
Kaiser Permanente-Walnut Creek
Walnut Creek, California, United States
Status: Recruiting
Contact: Louis Fehrenbacher - 626-564-3455
University of Colorado Cancer Center - Anschutz Cancer Pavilion
Aurora, Colorado, United States
Status: Recruiting
Contact: Saketh R. Guntupalli - 720-848-0650
Poudre Valley Hospital
Fort Collins, Colorado, United States
Status: Recruiting
Contact: Saketh R. Guntupalli - 720-848-0650
Hartford Hospital
Hartford, Connecticut, United States
Status: Recruiting
Contact: James S. Hoffman - 860-224-5660
Saint Francis Hospital and Medical Center
Hartford, Connecticut, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
The Hospital of Central Connecticut
New Britain, Connecticut, United States
Status: Recruiting
Contact: James S. Hoffman - 860-224-5660
Yale University
New Haven, Connecticut, United States
Status: Recruiting
Contact: Elena S. Ratner - 203-785-5702
Christiana Gynecologic Oncology LLC
Newark, Delaware, United States
Status: Recruiting
Contact: Stephen S. Grubbs - 302-733-6227
University of Florida
Gainesville, Florida, United States
Status: Recruiting
Contact: Merry J. Markham - 352-273-8675 - trials@cancer.ufl.edu
Florida Hospital Orlando
Orlando, Florida, United States
Status: Recruiting
Contact: James E. Kendrick - 407-303-5623
Women's Cancer Associates
Saint Petersburg, Florida, United States
Status: Recruiting
Contact: Megan D. Indermaur - 800-230-6203
Sarasota Memorial Hospital
Sarasota, Florida, United States
Status: Recruiting
Contact: James V. Fiorica - 941-917-2225
Emory University Hospital Midtown
Atlanta, Georgia, United States
Status: Recruiting
Contact: Namita Khanna - 404-778-1868
Emory University/Winship Cancer Institute
Atlanta, Georgia, United States
Status: Recruiting
Contact: Namita Khanna - 404-778-1868
Northside Hospital
Atlanta, Georgia, United States
Status: Recruiting
Contact: Guilherme Henrique C. Cantuaria - 404-303-3355 - clinicaltrials@northside.com
Dekalb Medical Center
Decatur, Georgia, United States
Status: Recruiting
Contact: Cyril O. Spann - 404-501-3279
Northeast Georgia Medical Center
Gainesville, Georgia, United States
Status: Recruiting
Contact: Andrew E. Green - 770-219-8800 - cancerpatient.navigator@nghs.com
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah, Georgia, United States
Status: Recruiting
Contact: William E. Richards - 800-622-6877
Oncare Hawaii Inc-Pali Momi
Aiea, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Pali Momi Medical Center
Aiea, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
The Cancer Center of Hawaii-Leeward
Ewa Beach, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Kuakini Medical Center
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Oncare Hawaii Inc-Kuakini
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Oncare Hawaii Inc-POB II
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
OnCare Hawaii-Liliha
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Queen's Medical Center
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Straub Clinic and Hospital
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
The Cancer Center of Hawaii-Liliha
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
University of Hawaii Cancer Center
Honolulu, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue, Hawaii, United States
Status: Recruiting
Contact: Michael E. Carney - 808-983-6090
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Rush - Copley Medical Center
Aurora, Illinois, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
Illinois CancerCare-Bloomington
Bloomington, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Canton
Canton, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Carthage
Carthage, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Northwestern University
Chicago, Illinois, United States
Status: Recruiting
Contact: Emily Berry - 312-695-1301 - cancer@northwestern.edu
Rush University Medical Center
Chicago, Illinois, United States
Status: Recruiting
Contact: Alfred S. Guirguis - 312-942-5498 - clinical_trials@rush.edu
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States
Status: Recruiting
Contact: Meaghan E. Tenney - 773-834-7424
Carle on Vermilion
Danville, Illinois, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
Cancer Care Center of Decatur
Decatur, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Decatur Memorial Hospital
Decatur, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Carle Physician Group-Effingham
Effingham, Illinois, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
Alexian Brothers Medical and Cancer Center
Elk Grove Village, Illinois, United States
Status: Recruiting
Contact: Kevin P. McKian - 847-952-7164 - fredianc@alexian.net
Illinois CancerCare-Eureka
Eureka, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, United States
Status: Recruiting
Contact: Jean A. Hurteau - 847-570-2109
Illinois CancerCare Galesburg
Galesburg, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
NorthShore University HealthSystem-Glenbrook Hospital
Glenview, Illinois, United States
Status: Recruiting
Contact: Jean A. Hurteau - 847-570-2109
NorthShore University HealthSystem-Highland Park Hospital
Highland Park, Illinois, United States
Status: Recruiting
Contact: Jean A. Hurteau - 847-570-2109
Sudarshan K Sharma MD Limted-Gynecologic Oncology
Hinsdale, Illinois, United States
Status: Recruiting
Contact: Sudarshan K. Sharma - 630-856-6757
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Macomb
Macomb, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
UC Comprehensive Cancer Center at Silver Cross
New Lennox, Illinois, United States
Status: Recruiting
Contact: Meaghan E. Tenney - 773-834-7424
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Pekin
Pekin, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Peoria
Peoria, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Peru
Peru, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Illinois CancerCare-Princeton
Princeton, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
North Shore Medical Center
Skokie, Illinois, United States
Status: Recruiting
Contact: Jean A. Hurteau - 847-570-2109
Central Illinois Hematology Oncology Center
Springfield, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Memorial Medical Center
Springfield, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Southern Illinois University School of Medicine
Springfield, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Springfield Clinic
Springfield, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Cancer Care Specialists of Illinois-Swansea
Swansea, Illinois, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Carle Cancer Center
Urbana, Illinois, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
The Carle Foundation Hospital
Urbana, Illinois, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
Cadence Cancer Center in Warrenville
Warrenville, Illinois, United States
Status: Recruiting
Contact: LaToya J. Perry - 630-208-4563 - kevin.tomczyk@delnor.com
Rush-Copley Healthcare Center
Yorkville, Illinois, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
Michiana Hematology Oncology PC-Crown Point
Crown Point, Indiana, United States
Status: Recruiting
Contact: Michael W. Method - 574-237-1328
Elkhart General Hospital
Elkhart, Indiana, United States
Status: Terminated
Michiana Hematology Oncology PC-Elkhart
Elkhart, Indiana, United States
Status: Recruiting
Contact: Michael W. Method - 574-237-1328
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, United States
Status: Recruiting
Contact: Frederick B. Stehman - 317-274-2552
Saint Vincent Oncology Center
Indianapolis, Indiana, United States
Status: Recruiting
Contact: Michael J. Callahan - 317-338-2194 - research@stvincent.org
IU Health La Porte Hospital
La Porte, Indiana, United States
Status: Terminated
Franciscan Saint Anthony Health-Michigan City
Michigan City, Indiana, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
Woodland Cancer Care Center
Michigan City, Indiana, United States
Status: Recruiting
Contact: Maria T. Grosse-Perdekamp - 800-446-5532
Michiana Hematology Oncology PC-Mishawaka
Mishawaka, Indiana, United States
Status: Recruiting
Contact: Michael W. Method - 574-237-1328
Saint Joseph Regional Medical Center-Mishawaka
Mishawaka, Indiana, United States
Status: Recruiting
Contact: Michael W. Method - 574-237-1328
Michiana Hematology Oncology PC-South Bend
South Bend, Indiana, United States
Status: Recruiting
Contact: Michael W. Method - 574-237-1328
Michiana Hematology Oncology-PC Westville
Westville, Indiana, United States
Status: Recruiting
Contact: Michael W. Method - 574-237-1328
Mary Greeley Medical Center
Ames, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
McFarland Clinic PC-William R Bliss Cancer Center
Ames, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
McFarland Clinic PC-Boone
Boone, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa, United States
Status: Recruiting
Contact: Mehmet S. Copur - 800-998-2119
Mercy Cancer Center-West Lakes
Clive, Iowa, United States
Status: Recruiting
Contact: Mehmet S. Copur - 800-998-2119
Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa, United States
Status: Recruiting
Contact: Mehmet S. Copur - 800-998-2119
Mercy Medical Center - Des Moines
Des Moines, Iowa, United States
Status: Recruiting
Contact: Mehmet S. Copur - 800-998-2119
McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, United States
Status: Recruiting
Contact: David P. Bender - 800-237-1225
McFarland Clinic PC-Jefferson
Jefferson, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
McFarland Clinic PC-Marshalltown
Marshalltown, Iowa, United States
Status: Recruiting
Contact: Joseph J. Merchant - 515-239-2621
Mercy Medical Center - North Iowa
Mason City, Iowa, United States
Status: Recruiting
Contact: Arvind Y. Vemula - 800-433-3883
Saint Elizabeth Medical Center South
Edgewood, Kentucky, United States
Status: Active, not recruiting
Saint Luke Hospital
Fort Thomas, Kentucky, United States
Status: Recruiting
Contact: Kevin M. Schuler - 859-301-5473 - darla.hehman@stelizabeth.com
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, United States
Status: Recruiting
Contact: Frederick R. Ueland - 859-257-3379
Woman's Hospital
Baton Rouge, Louisiana, United States
Status: Recruiting
Contact: Giles Fort - 225-231-5296 - Ericka.Seidemann@womans.org
Ochsner Medical Center Jefferson
New Orleans, Louisiana, United States
Status: Recruiting
Contact: Richard C. Kline - 888-562-4763
Maine Medical Center- Scarborough Campus
Scarborough, Maine, United States
Status: Recruiting
Contact: Christopher J. Darus - 207-885-7565
Greater Baltimore Medical Center
Baltimore, Maryland, United States
Status: Recruiting
Contact: Paul Celano - 443-849-3706
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, United States
Status: Recruiting
Contact: Deborah K. Armstrong - 410-955-8804 - jhcccro@jhmi.edu
Sinai Hospital of Baltimore
Baltimore, Maryland, United States
Status: Recruiting
Contact: Mark A. Miller - 877-441-7957
Walter Reed National Military Medical Center
Bethesda, Maryland, United States
Status: Recruiting
Contact: Michael P. Stany - 301-319-2100
Brigham and Women's Hospital
Boston, Massachusetts, United States
Status: Recruiting
Contact: Neil S. Horowitz - 617-724-5200
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Status: Recruiting
Contact: Neil S. Horowitz - 617-724-5200
Tufts Medical Center
Boston, Massachusetts, United States
Status: Recruiting
Contact: Young B. Kim - 617-636-5000 - ContactUsCancerCenter@TuftsMedicalCenter.org
Lowell General Hospital
Lowell, Massachusetts, United States
Status: Recruiting
Contact: Blair Ardman - 978-788-7084 - ghincks@lowellgeneral.org
University of Massachusetts Memorial Health Care
Worcester, Massachusetts, United States
Status: Recruiting
Contact: Susan L. Zweizig - 508-856-3216 - cancer.research@umassmed.edu
Michigan Cancer Research Consortium CCOP
Ann Arbor, Michigan, United States
Status: Terminated
Saint Joseph Mercy Hospital
Ann Arbor, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States
Status: Active, not recruiting
Bronson Battle Creek
Battle Creek, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Oakwood Hospital and Medical Center
Dearborn, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, United States
Status: Recruiting
Contact: Robert T. Morris - 313-576-9363
Green Bay Oncology - Escanaba
Escanaba, Michigan, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
Weisberg Cancer Treatment Center
Farmington Hills, Michigan, United States
Status: Recruiting
Contact: Robert T. Morris - 313-576-9363
Genesys Hurley Cancer Institute
Flint, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Hurley Medical Center
Flint, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids, Michigan, United States
Status: Active, not recruiting
Mercy Health Saint Mary's
Grand Rapids, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Green Bay Oncology - Iron Mountain
Iron Mountain, Michigan, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
Allegiance Health
Jackson, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
West Michigan Cancer Center
Kalamazoo, Michigan, United States
Status: Recruiting
Contact: Sunil Nagpal - 269-373-7458
Sparrow Hospital
Lansing, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Saint Mary Mercy Hospital
Livonia, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Mercy Health Mercy Campus
Muskegon, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
Saint Joseph Mercy Oakland
Pontiac, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Saint Joseph Mercy Port Huron
Port Huron, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Spectrum Health Reed City Hospital
Reed City, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, United States
Status: Recruiting
Contact: Jayson B. Field - 248-551-7695
Saint Mary's of Michigan
Saginaw, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Munson Medical Center
Traverse City, Michigan, United States
Status: Recruiting
Contact: Gilbert D. Padula - 616-685-5225 - connie.szczepanek@grcop.org
William Beaumont Hospital - Troy
Troy, Michigan, United States
Status: Recruiting
Contact: Jayson B. Field - 248-551-7695
Saint John Macomb-Oakland Hospital
Warren, Michigan, United States
Status: Recruiting
Contact: Philip J. Stella - 734-712-4673
Sanford Clinic North-Bemidgi
Bemidji, Minnesota, United States
Status: Recruiting
Contact: Maria C. Bell - 218-333-5000
Mercy Hospital
Coon Rapids, Minnesota, United States
Status: Recruiting
Contact: Matthew P. Boente - 952-993-1517 - MMCCOP@parknicollet.com
Fairview-Southdale Hospital
Edina, Minnesota, United States
Status: Recruiting
Contact: Matthew P. Boente - 952-993-1517 - MMCCOP@parknicollet.com
Abbott-Northwestern Hospital
Minneapolis, Minnesota, United States
Status: Recruiting
Contact: Matthew P. Boente - 952-993-1517 - MMCCOP@parknicollet.com
Mayo Clinic
Rochester, Minnesota, United States
Status: Recruiting
Contact: Jamie N. Bakkum-Gamez - 507-538-7623
Metro-Minnesota NCI Community Oncology Research Program
Saint Louis Park, Minnesota, United States
Status: Terminated
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, United States
Status: Recruiting
Contact: Matthew P. Boente - 952-993-1517 - MMCCOP@parknicollet.com
United Hospital
Saint Paul, Minnesota, United States
Status: Recruiting
Contact: Matthew P. Boente - 952-993-1517 - MMCCOP@parknicollet.com
Lakeview Hospital
Stillwater, Minnesota, United States
Status: Recruiting
Contact: Matthew P. Boente - 952-993-1517 - MMCCOP@parknicollet.com
Minnesota Oncology and Hematology PA-Woodbury
Woodbury, Minnesota, United States
Status: Recruiting
Contact: Matthew P. Boente - 952-993-1517 - MMCCOP@parknicollet.com
Saint Dominic-Jackson Memorial Hospital
Jackson, Mississippi, United States
Status: Recruiting
Contact: Donald P. Seago - 601-200-3300
University of Mississippi Medical Center
Jackson, Mississippi, United States
Status: Recruiting
Contact: James T. Thigpen - 601-815-6700
Saint Francis Medical Center
Cape Girardeau, Missouri, United States
Status: Recruiting
Contact: James L. Wade - 217-876-4740 - kcheek@dmhhs.org
Phelps County Regional Medical Center
Rolla, Missouri, United States
Status: Recruiting
Contact: Jay W. Carlson - 800-821-7532
Saint John's Clinic-Rolla-Cancer and Hematology
Rolla, Missouri, United States
Status: Recruiting
Contact: Jay W. Carlson - 800-821-7532
Mercy Hospital Saint Louis
Saint Louis, Missouri, United States
Status: Recruiting
Contact: Jay W. Carlson - 800-821-7532
Washington University School of Medicine
Saint Louis, Missouri, United States
Status: Recruiting
Contact: David G. Mutch - 800-600-3606 - info@ccadmin.wustl.edu
Cancer Research for the Ozarks NCORP
Springfield, Missouri, United States
Status: Terminated
CoxHealth South Hospital
Springfield, Missouri, United States
Status: Recruiting
Contact: Jay W. Carlson - 800-821-7532
Mercy Hospital Springfield
Springfield, Missouri, United States
Status: Recruiting
Contact: Jay W. Carlson - 800-821-7532
CHI Health Saint Francis
Grand Island, Nebraska, United States
Status: Recruiting
Contact: Mehmet S. Copur - 800-998-2119
Nebraska Methodist Hospital
Omaha, Nebraska, United States
Status: Recruiting
Contact: Peter C. Morris - 402-354-7939 - kathryn.bartz@nmhs.org
Women's Cancer Center of Nevada
Las Vegas, Nevada, United States
Status: Recruiting
Contact: Nicola M. Spirtos - 702-851-4672
Center of Hope at Renown Medical Center
Reno, Nevada, United States
Status: Recruiting
Contact: Peter C. Lim - 866-513-8227
Renown Regional Medical Center
Reno, Nevada, United States
Status: Recruiting
Contact: Peter C. Lim - 866-513-8227
Wentworth-Douglass Hospital
Dover, New Hampshire, United States
Status: Recruiting
Contact: John O. Schorge - 877-726-5130
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States
Status: Recruiting
Contact: Leslie R. DeMars - 800-639-6918 - cancer.research.nurse@dartmouth.edu
Memorial Sloan Kettering Cancer Center at Basking Ridge
Basking Ridge, New Jersey, United States
Status: Recruiting
Contact: Carol Aghajanian - 212-639-7202
Cooper Hospital University Medical Center
Camden, New Jersey, United States
Status: Recruiting
Contact: David P. Warshal - 856-325-6757
Morristown Medical Center
Morristown, New Jersey, United States
Status: Recruiting
Contact: Paul B. Heller - 973-971-5900
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County
Mount Holly, New Jersey, United States
Status: Recruiting
Contact: Randolph B. Deger - 888-847-8823
Overlook Hospital
Summit, New Jersey, United States
Status: Recruiting
Contact: Paul B. Heller - 973-971-5900
MD Anderson Cancer Center at Cooper-Voorhees
Voorhees, New Jersey, United States
Status: Recruiting
Contact: David P. Warshal - 856-325-6757
Virtua West Jersey Hospital Voorhees
Voorhees, New Jersey, United States
Status: Recruiting
Contact: Randolph B. Deger - 888-847-8823
Southwest Gynecologic Oncology Associates Inc
Albuquerque, New Mexico, United States
Status: Active, not recruiting
University of New Mexico
Albuquerque, New Mexico, United States
Status: Active, not recruiting
Women's Cancer Care Associates LLC
Albany, New York, United States
Status: Recruiting
Contact: Daniel C. Kredentser - 518-458-1390
The New York Methodist Hospital
Brooklyn, New York, United States
Status: Recruiting
Contact: Katherine Economos - 718-780-5240
Memorial Sloan Kettering Cancer Center Commack
Commack, New York, United States
Status: Recruiting
Contact: Carol Aghajanian - 212-639-7202
Winthrop University Hospital
Mineola, New York, United States
Status: Recruiting
Contact: Jeannine A. Villella - 866-946-8476
Columbia University Medical Center
New York, New York, United States
Status: Recruiting
Contact: Thomas J. Herzog - 513-558-4553 - uchealthnews@uc.edu
Laura and Issac Perlmutter Cancer Center at NYU Langone
New York, New York, United States
Status: Recruiting
Contact: Stephanie V. Blank - 212-263-4434 - prmc.coordinator@nyumc.org
Memorial Sloan-Kettering Cancer Center
New York, New York, United States
Status: Recruiting
Contact: Carol Aghajanian - 212-639-7202
Mount Sinai Medical Center
New York, New York, United States
Status: Recruiting
Contact: Monica P. Hayes - 212-824-7320 - jenny.figueroa@mssm.edu
Memorial Sloan-Kettering Cancer Center Rockville Centre
Rockville Centre, New York, United States
Status: Recruiting
Contact: Carol Aghajanian - 212-639-7202
Memorial Sloan-Kettering Cancer Center Sleepy Hollow
Sleepy Hollow, New York, United States
Status: Recruiting
Contact: Carol Aghajanian - 212-639-7202
Stony Brook University Medical Center
Stony Brook, New York, United States
Status: Recruiting
Contact: Jeannine A. Villella - 866-946-8476
Westchester Medical Center
Valhalla, New York, United States
Status: Recruiting
Contact: Sean S. Tedjarati - 800-862-2215
Memorial Sloan-Kettering Cancer Center West Harrison
West Harrison, New York, United States
Status: Recruiting
Contact: Carol Aghajanian - 212-639-7202
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
Status: Recruiting
Contact: Linda Van Le - 877-668-0683 - cancerclinicaltrials@med.unc.edu
Carolinas Medical Center/Levine Cancer Institute
Charlotte, North Carolina, United States
Status: Recruiting
Contact: Robert V. Higgins - 704-355-2884
Novant Health Presbyterian Medical Center
Charlotte, North Carolina, United States
Status: Recruiting
Contact: John M. McDonald - 704-384-5369
Carolinas HealthCare System NorthEast
Concord, North Carolina, United States
Status: Recruiting
Contact: Robert V. Higgins - 704-355-2884
Duke University Medical Center
Durham, North Carolina, United States
Status: Recruiting
Contact: Angeles A. Secord - 888-275-3853
Park Ridge Hospital Breast Health Center
Hendersonville, North Carolina, United States
Status: Recruiting
Contact: David Griffin - 864-512-1000
Novant Health Oncology Specialists-Kernersville
Kernersville, North Carolina, United States
Status: Recruiting
Contact: Arvind N. Bakhru - 321-841-7246 - CancerClinicalTrials@orlandohealth.com
Novant Health Oncology Specialists-Davidson County
Lexington, North Carolina, United States
Status: Recruiting
Contact: Arvind N. Bakhru - 321-841-7246 - CancerClinicalTrials@orlandohealth.com
Novant Health Oncology Specialists-Mount Airy
Mount Airy, North Carolina, United States
Status: Recruiting
Contact: Arvind N. Bakhru - 321-841-7246 - CancerClinicalTrials@orlandohealth.com
FirstHealth of the Carolinas-Moore Regional Hosiptal
Pinehurst, North Carolina, United States
Status: Recruiting
Contact: Michael J. Sundborg - 910-715-2200
Duke Raleigh Hospital
Raleigh, North Carolina, United States
Status: Recruiting
Contact: Angeles A. Secord - 888-275-3853
Novant Health Oncology Specialists-Statesville
Stateville, North Carolina, United States
Status: Recruiting
Contact: Arvind N. Bakhru - 321-841-7246 - CancerClinicalTrials@orlandohealth.com
Novant Health Oncology Specialists-Wilkesboro
Wilkesboro, North Carolina, United States
Status: Recruiting
Contact: Arvind N. Bakhru - 321-841-7246 - CancerClinicalTrials@orlandohealth.com
New Hanover Regional Medical Center/Zimmer Cancer Center
Wilmington, North Carolina, United States
Status: Recruiting
Contact: Walter H. Gajewski - 910-342-3000
Novant Health Oncology Specialists
Winston-Salem, North Carolina, United States
Status: Recruiting
Contact: Arvind N. Bakhru - 321-841-7246 - CancerClinicalTrials@orlandohealth.com
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Status: Recruiting
Contact: Samuel S. Lentz - 336-713-6771
Winston-Salem Health Care
Winston-Salem, North Carolina, United States
Status: Recruiting
Contact: Arvind N. Bakhru - 321-841-7246 - CancerClinicalTrials@orlandohealth.com
Sanford Bismarck Medical Center
Bismarck, North Dakota, United States
Status: Recruiting
Contact: Maria C. Bell - 218-333-5000
Roger Maris Cancer Center
Fargo, North Dakota, United States
Status: Recruiting
Contact: Maria C. Bell - 218-333-5000
Sanford Clinic North-Fargo
Fargo, North Dakota, United States
Status: Recruiting
Contact: Maria C. Bell - 218-333-5000
Sanford Medical Center-Fargo
Fargo, North Dakota, United States
Status: Recruiting
Contact: Maria C. Bell - 218-333-5000
Summa Akron City Hospital/Cooper Cancer Center
Akron, Ohio, United States
Status: Active, not recruiting
Bethesda North Hospital
Cincinnati, Ohio, United States
Status: Recruiting
Contact: Mehmet S. Copur - 800-998-2119
Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio, United States
Status: Recruiting
Contact: Mehmet S. Copur - 800-998-2119
University of Cincinnati
Cincinnati, Ohio, United States
Status: Active, not recruiting
Case Western Reserve University
Cleveland, Ohio, United States
Status: Recruiting
Contact: Steven E. Waggoner - 800-641-2422
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio, United States
Status: Recruiting
Contact: Peter G. Rose - 866-223-8100
Cleveland Clinic Foundation
Cleveland, Ohio, United States
Status: Recruiting
Contact: Peter G. Rose - 866-223-8100
Columbus CCOP
Columbus, Ohio, United States
Status: Terminated
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States
Status: Recruiting
Contact: David M. O'Malley - 800-293-5066 - Jamesline@osumc.edu
Riverside Methodist Hospital
Columbus, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-488-2745 - sheree@columbusccop.org
The Mark H Zangmeister Center
Columbus, Ohio, United States
Status: Recruiting
Contact: John P. Kuebler - 614-488-2745 - sheree@columbusccop.org
Good Samaritan Hospital - Dayton
Dayton, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Grandview Hospital
Dayton, Ohio, United States
Status: Active, not recruiting
Miami Valley Hospital
Dayton, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Samaritan North Health Center
Dayton, Ohio, United States
Status: Recruiting
Contact: Howard M. Gross - 937-775-1350
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio, United States
Status: Recruiting
Contact: Peter G. Rose - 866-223-8100
Lake University Ireland Cancer Center
Mentor, Ohio, United States
Status: Recruiting
Contact: Steven E. Waggoner - 800-641-2422
Wright-Patterson Medical Center
Wright-Patterson Afb, Ohio, United States
Status: Recruiting
Contact: Yovanni Casablanca - 937-257-1398
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
Status: Recruiting
Contact: Robert S. Mannel - 405-271-4272 - julie-traylor@ouhsc.edu
Tulsa Cancer Institute
Tulsa, Oklahoma, United States
Status: Recruiting
Contact: Robert S. Mannel - 405-271-4272 - julie-traylor@ouhsc.edu
Abington Memorial Hospital
Abington, Pennsylvania, United States
Status: Recruiting
Contact: Parviz Hanjani - 215-481-2402
Geisinger Medical Center
Danville, Pennsylvania, United States
Status: Recruiting
Contact: Radhika P. Gogoi - 570-271-5251
Adams Cancer Center
Gettysburg, Pennsylvania, United States
Status: Recruiting
Contact: Mark A. Miller - 877-441-7957
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania, United States
Status: Recruiting
Contact: Alexander B. Olawaiye - 412-647-2811
Cherry Tree Cancer Center
Hanover, Pennsylvania, United States
Status: Recruiting
Contact: Mark A. Miller - 877-441-7957
Geisinger Medical Center-Cancer Center Hazleton
Hazleton, Pennsylvania, United States
Status: Recruiting
Contact: Radhika P. Gogoi - 570-271-5251
Geisinger Medical Oncology at Evangelical Community Hospital
Lewisburg, Pennsylvania, United States
Status: Recruiting
Contact: Radhika P. Gogoi - 570-271-5251
Lewistown Hospital
Lewistown, Pennsylvania, United States
Status: Recruiting
Contact: Radhika P. Gogoi - 570-271-5251
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States
Status: Recruiting
Contact: Angela Jain - 215-728-4790
Temple University Hospital
Philadelphia, Pennsylvania, United States
Status: Active, not recruiting
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States
Status: Recruiting
Contact: Christine H. Kim - 215-955-6084
University of Pennsylvania/Abramson Cancer Center
Philadelphia, Pennsylvania, United States
Status: Active, not recruiting
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, United States
Status: Recruiting
Contact: Alexander B. Olawaiye - 412-647-2811
UPMC-Magee Womens Hospital
Pittsburgh, Pennsylvania, United States
Status: Recruiting
Contact: Alexander B. Olawaiye - 412-647-2811
UPMC-Passavant Hospital
Pittsburgh, Pennsylvania, United States
Status: Recruiting
Contact: Alexander B. Olawaiye - 412-647-2811
Geisinger Medical Oncology-Pottsville
Pottsville, Pennsylvania, United States
Status: Recruiting
Contact: Radhika P. Gogoi - 570-271-5251
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, United States
Status: Recruiting
Contact: Alexander B. Olawaiye - 412-647-2811
Geisinger Medical Group
State College, Pennsylvania, United States
Status: Recruiting
Contact: Radhika P. Gogoi - 570-271-5251
UPMC Uniontown Hospital Radiation Oncology
Uniontown, Pennsylvania, United States
Status: Recruiting
Contact: Alexander B. Olawaiye - 412-647-2811
Chester County Hospital
West Chester, Pennsylvania, United States
Status: Recruiting
Contact: William E. Luginbuhl - 610-431-5297
Reading Hospital
West Reading, Pennsylvania, United States
Status: Recruiting
Contact: Bernice L. Robinson-Bennett - 610-988-9323
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania, United States
Status: Recruiting
Contact: Radhika P. Gogoi - 570-271-5251
WellSpan Health-York Hospital
York, Pennsylvania, United States
Status: Recruiting
Contact: Mark A. Miller - 877-441-7957
Women and Infants Hospital
Providence, Rhode Island, United States
Status: Recruiting
Contact: Paul A. DiSilvestro - 401-274-1122
AnMed Health Cancer Center
Anderson, South Carolina, United States
Status: Recruiting
Contact: David Griffin - 864-512-1000
Medical University of South Carolina
Charleston, South Carolina, United States
Status: Recruiting
Contact: Whitney S. Graybill - 843-792-9321
Saint Francis Hospital
Greenville, South Carolina, United States
Status: Recruiting
Contact: David Griffin - 864-512-1000
Gibbs Cancer Center-Pelham
Greer, South Carolina, United States
Status: Recruiting
Contact: David Griffin - 864-512-1000
Carolina Blood and Cancer Care Associates PA-Lancaster
Lancaster, South Carolina, United States
Status: Recruiting
Contact: David Griffin - 864-512-1000
Carolina Blood and Cancer Care Associates PA
Rock Hill, South Carolina, United States
Status: Recruiting
Contact: David Griffin - 864-512-1000
Spartanburg Medical Center
Spartanburg, South Carolina, United States
Status: Recruiting
Contact: David Griffin - 864-512-1000
Black Hills Obstetrics and Gynecology
Rapid City, South Dakota, United States
Status: Recruiting
Contact: Helen L. Frederickson - 605-343-9224
Rapid City Regional Hospital
Rapid City, South Dakota, United States
Status: Recruiting
Contact: Helen L. Frederickson - 605-343-9224
Avera Cancer Institute
Sioux Falls, South Dakota, United States
Status: Recruiting
Contact: Luis A. Rojas-Espaillat - 800-657-4377 - Jan.Healy@avera.org
Sanford Cancer Center-Oncology Clinic
Sioux Falls, South Dakota, United States
Status: Recruiting
Contact: Maria C. Bell - 218-333-5000
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, United States
Status: Recruiting
Contact: Maria C. Bell - 218-333-5000
Chattanooga's Program in Women's Oncology
Chattanooga, Tennessee, United States
Status: Recruiting
Contact: Stephen E. DePasquale - 423-266-3636
Texas Oncology - Central Austin Cancer Center
Austin, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Texas Oncology - South Austin Cancer Center
Austin, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Texas Oncology-Austin Midtown
Austin, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
University Medical Center Brackenridge
Austin, Texas, United States
Status: Recruiting
Contact: John L. Dalrymple - 512-324-7991
Texas Oncology Bedford
Bedford, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Texas Oncology at Baylor Charles A Sammons Cancer Center
Dallas, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, United States
Status: Recruiting
Contact: David S. Miller - 214-648-7097
Texas Oncology Fort Worth at 12th Avenue
Fort Worth, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Lyndon Baines Johnson General Hospital
Houston, Texas, United States
Status: Recruiting
Contact: Pamela T. Soliman - 713-792-3245
M D Anderson Cancer Center
Houston, Texas, United States
Status: Recruiting
Contact: Pamela T. Soliman - 713-792-3245
Memorial Hermann Texas Medical Center
Houston, Texas, United States
Status: Active, not recruiting
The Methodist Hospital System
Houston, Texas, United States
Status: Recruiting
Contact: Aparna A. Kamat - 713-790-2700
Texas Oncology-Longview Cancer Center
Longview, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Texas Oncology Cancer Center Sugar Land
Sugar Land, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Texas Oncology-The Woodlands
The Woodlands, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Tyler Cancer Center
Tyler, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
Deke Slayton Cancer Center
Webster, Texas, United States
Status: Recruiting
Contact: Michael A. Bookman - 520-626-9008
American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
Sandra L Maxwell Cancer Center
Cedar City, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
Logan Regional Hospital
Logan, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
Intermountain Medical Center
Murray, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
McKay-Dee Hospital Center
Ogden, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
Utah Valley Regional Medical Center
Provo, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
Dixie Medical Center Regional Cancer Center
Saint George, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, United States
Status: Recruiting
Contact: Theresa L. Werner - 801-581-4477 - clinical.trials@hci.utah.edu
LDS Hospital
Salt Lake City, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
Utah Cancer Specialists-Salt Lake City
Salt Lake City, Utah, United States
Status: Recruiting
Contact: Xylina T. Gregg - 801-933-6070 - research@utahcancer.com
Southwestern Vermont Medical Center
Bennington, Vermont, United States
Status: Recruiting
Contact: Leslie R. DeMars - 800-639-6918 - cancer.research.nurse@dartmouth.edu
University of Vermont Medical Center
Burlington, Vermont, United States
Status: Recruiting
Contact: Cheung Wong - 802-656-8990
University of Virginia Cancer Center
Charlottesville, Virginia, United States
Status: Recruiting
Contact: Susan C. Modesitt - 434-243-6143
Henrico Doctor's Hospital
Richmond, Virginia, United States
Status: Recruiting
Contact: Jori S. Carter - 804-628-1939
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, United States
Status: Recruiting
Contact: Jori S. Carter - 804-628-1939
Virginia Gynecologic Oncology
Richmond, Virginia, United States
Status: Recruiting
Contact: Jori S. Carter - 804-628-1939
Carilion Clinic Gynecological Oncology
Roanoke, Virginia, United States
Status: Recruiting
Contact: Janet L. Osborne - 540-985-8510
Highline Medical Center-Main Campus
Burien, Washington, United States
Status: Recruiting
Contact: Mehmet S. Copur - 800-998-2119
MultiCare Gig Harbor Medical Park
Gig Harbor, Washington, United States
Status: Recruiting
Contact: John A. Keech - 907-458-5380
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Seattle, Washington, United States
Status: Recruiting
Contact: Heidi J. Gray - 206-616-8289
Northwest Hospital
Seattle, Washington, United States
Status: Recruiting
Contact: Heidi J. Gray - 206-616-8289
Seattle Cancer Care Alliance
Seattle, Washington, United States
Status: Recruiting
Contact: Heidi J. Gray - 206-616-8289
University of Washington Medical Center
Seattle, Washington, United States
Status: Recruiting
Contact: Heidi J. Gray - 206-616-8289
Women's Cancer Center of Seattle
Seattle, Washington, United States
Status: Recruiting
Contact: Heidi J. Gray - 206-616-8289
Multicare Health System
Tacoma, Washington, United States
Status: Recruiting
Contact: John A. Keech - 907-458-5380
Edwards Comprehensive Cancer Center
Huntington, West Virginia, United States
Status: Recruiting
Contact: Maria R. Tria Tirona - 304-399-6617
Monongalia Hospital
Morgantown, West Virginia, United States
Status: Recruiting
Contact: Jamie L. Lesnock - 888-823-5923 - ctsucontact@westat.com
Green Bay Oncology at Saint Vincent Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
Green Bay Oncology Limited at Saint Mary's Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
Saint Mary's Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
Saint Vincent Hospital
Green Bay, Wisconsin, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States
Status: Recruiting
Contact: Lisa M. Barroilhet - 877-405-6866
Holy Family Memorial Hospital
Manitowoc, Wisconsin, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
Froedtert and the Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Status: Recruiting
Contact: William H. Bradley - 414-805-4380
D N Greenwald Center
Mukwonago, Wisconsin, United States
Status: Recruiting
Contact: Janet G. Drake - 262-928-7632
Oconomowoc Memorial Hospital-ProHealth Care Inc
Oconomowoc, Wisconsin, United States
Status: Recruiting
Contact: Janet G. Drake - 262-928-7632
Green Bay Oncology - Oconto Falls
Oconto Falls, Wisconsin, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
Green Bay Oncology - Sturgeon Bay
Sturgeon Bay, Wisconsin, United States
Status: Recruiting
Contact: Jonathan E. Tammela - 920-433-8889
Waukesha Memorial Hospital
Waukesha, Wisconsin, United States
Status: Recruiting
Contact: Janet G. Drake - 262-928-7632
Aspirus Regional Cancer Center
Wausau, Wisconsin, United States
Status: Recruiting
Contact: Christopher G. Peterson - 877-405-6866
Start Date
March 2014
Sponsors
Gynecologic Oncology Group
Source
Gynecologic Oncology Group
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page