BRCA-Screening in Ovarian Cancer
Conditions
BRCA Status - Ovarian Cancer
Conditions: official terms
Ovarian Neoplasms
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Intervention
Name: Testing of BRCA status regarding germline and somatic mutation
Type: Genetic
Overall Status
Recruiting
Summary
The aim of this prospective registration and translational research study is to evaluate the incidence of BRCA regarding germline and somatic mutations.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Female
Criteria: Inclusion Criteria:

- Female ovarian cancer patients aged >= 18 years.

- Women with first diagnosis of epithelial ovarian cancer OR women diagnosed with platinum-sensitive recurrent ovarian cancer.

- Multiple platinum based prior therapies are allowed.

Exclusion Criteria:

- Non-epithelial ovarian malignancy.

- Platinum-resistant or refractory disease.

- Paraffin embedded tumor samples not available.
Locations
Charité - Universitätsmedizin Berlin
Berlin, Germany
Status: Not yet recruiting
Universitätsklinik Carl Gustav Carus
Dresden, Germany
Status: Not yet recruiting
Evangelisches Krankenhaus
Düsseldorf, Germany
Status: Recruiting
Kliniken Essen-Mitte
Essen, Germany
Status: Recruiting
Universitätsklinikum Essen
Essen, Germany
Status: Not yet recruiting
Universitätsklinikum Frankfurt
Frankfurt/Main, Germany
Status: Not yet recruiting
Universitätsklinikum Hamburg-Eppendorf
Hamburg, Germany
Status: Not yet recruiting
Medizinische Hochschule Hannover
Hannover, Germany
Status: Recruiting
NCT Heidelberg
Heidelberg, Germany
Status: Not yet recruiting
Universitätsklinikum Schleswig-Holstein
Kiel, Germany
Status: Not yet recruiting
Zentrum für Gynäkologische Onkologie
Kiel, Germany
Status: Not yet recruiting
Universitätsklinikum Schleswig-Holstein
Lübeck, Germany
Status: Not yet recruiting
Universitätsklinikum Gießen und Marburg
Marburg, Germany
Status: Not yet recruiting
Klinikum rechts der Isar
München, Germany
Status: Not yet recruiting
LMU München, Klinik Großhadern
München, Germany
Status: Not yet recruiting
Sana Klinikum Offenbach
Offenbach, Germany
Status: Not yet recruiting
Universitäts-Frauenklinik
Tübingen, Germany
Status: Recruiting
Universitätsklinikum Ulm
Ulm, Germany
Status: Not yet recruiting
Dr. Horst Schmidt Kliniken
Wiesbaden, Germany
Status: Not yet recruiting
Universitätsklinikum Würzburg
Würzburg, Germany
Status: Not yet recruiting
Start Date
March 2015
Completion Date
December 2020
Sponsors
AGO Research GmbH
Source
AGO Research GmbH
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page