Study of the Immune Response After Vaccination in Multiple Myeloma Patients
Conditions
Multiple Myeloma - Myeloma, Multiple - Myeloma-Multiple
Conditions: official terms
Multiple Myeloma - Neoplasms, Plasma Cell
Conditions: Keywords
influenza, pneumococcal, pneumonia, vaccine, immunization, #CAImmun, Immuno-oncology, supportive care, vaccination
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Case Control, Time Perspective: Prospective
Overall Status
Recruiting
Summary
This study will collect blood samples from healthy volunteers and volunteers with multiple myeloma who are going to get the seasonal flu or pneumonia vaccines.

The main goal of the study is to start to identify differences in the immune response between multiple myeloma patients and people who don't have multiple myeloma. We hope this will provide important information about the best way and time to vaccinate multiple myeloma patients to flu and pneumonia.
Detailed Description
This study will consist of a prospective blood sample collection to gather baseline data to confirm antibody protection from vaccines in the Aurora Health Care multiple myeloma (MM) patients.

The overall goal of this study is to obtain a normative dataset for non-MM control populations as well as determining baseline IgG levels to seasonal influenza A, influenza B, pneumococcal polysaccharide, and tetanus toxoid and confirmation of antibody protection from vaccines with assays based upon WHO standards of detection.

This is part of a series of studies designed to provide important information about the best way and time to vaccinate MM patients to flu and pneumonia vaccines and to gather additional information about MM and immune function.
Criteria for eligibility
Healthy Volunteers: Accepts Healthy Volunteers
Maximum Age: N/A
Minimum Age: 50 Years
Gender: Both
Criteria: Inclusion Criteria:

- 50 years old or over

- planning on getting the seasonal flu and/or pneumonia vaccine as part of normal care

- have multiple myeloma, or don't have multiple myeloma and want to serve as a health control

Exclusion Criteria:

- do not meet inclusion criteria
Location
Aurora Health Care
Milwaukee, Wisconsin, United States
Status: Recruiting
Contact: Brittany Last - 414-649-5608 - brittany.last@aurora.org
Start Date
December 2014
Completion Date
November 2016
Sponsors
Michael A. Thompson, MD, PhD
Source
Aurora Health Care
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page