Proton Magnetic Resonance Spectroscopy of Normal Breast Tissues in Women Volunteers
Breast Neoplasms
Conditions: official terms
Breast Neoplasms
Conditions: Keywords
Magnetic resonance imaging,, breast disease
Study Type
Study Phase
Study Design
Observational Model: Defined Population, Primary Purpose: Screening, Time Perspective: Cross-Sectional
Overall Status
Magnetic resonance spectroscopy (MRS) is a diagnostic technique in MRI that distinguishes various metabolites on the basis of their slightly different chemical shifts or resonance frequencies. The Proton is the most abundant nucleus in the body. We will try to establish the typical proton MRS pattern of normal women breasts to be a guideline for future further investigations.
Detailed Description
There are few reports regarding proton MRS in normal female breasts. The fibroglandular tissues and fat are the two major gross components in the breast. The water content in the fibroglandular tissues is much higher than that in the fat. There is still no documented report discussing proton MRS in normal female breasts of premenopausal and postmenopausal women. Our study is to evaluate the proton MRS findings among normal premenopausal and postmenopausal women breasts, to find out if there are statistical differences on the main proton MRS patterns, water and lipid peak intensities and ratios between the two groups.
Criteria for eligibility
Healthy Volunteers: Accepts Healthy Volunteers
Maximum Age: N/A
Minimum Age: 30 Years
Gender: Female
Criteria: Inclusion Criteria:

- women age ranged 30 years of age or older, with normal mammograms or ultrasound in recent 3 months

Exclusion Criteria:

- any women not fulfilling the inclusion criteria
National Taiwan University Hospital
Taipei, Taiwan
Status: Recruiting
Contact: Jane Wang, MD - 886-2-23123456 -
Start Date
January 2005
Completion Date
December 2005
National Taiwan University Hospital
National Taiwan University Hospital
Record processing date processed this data on July 28, 2015 page