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Role of Routine Nasogastric Decompression After Subtotal Gastrectomy
Conditions
Cancer of Stomach
Conditions: official terms
Stomach Neoplasms
Study Type
Interventional
Study Phase
Phase 3
Study Design
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Intervention
Name: nasogastric tube
Type: Device
Overall Status
Recruiting
Summary
The aim of the study is to evaluate whether subtotal gastrectomy without post-operative nasogastric decompression is better in terms of early post-operative bowel function and chest complication.
Detailed Description
Nasogastric decompression is an intra-operative routine in most of the time to facilitate exposure of operative field during elective subtotal gastrectomy, but whether it should be retained post-operatively is controversial. Nasogastric decompression helps to drain the gastric remnant in case there is edema around the gastrojejunostomy, ileus and delayed gastric emptying, which can theoretically relieve nausea and abdominal distension. Besides, it may help decrease diaphragmatic splintage and hence decrease chance of chest infection if ileus occurs. However, nasogastric intubation could cause patient discomfort; also it has been shown that it would cause gastroesophageal reflux which may be associated with chest complication. There have been studies showing that routine post-operative nasogastric decompression is not necessary for gastrectomy in general, but the role in subtotal gastrectomy for stomach cancer is not well defined.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Weeks
Gender: Both
Criteria: Inclusion Criteria:All patients suffering from carcinoma of stomach, decided for operation
- subtotal, D1/D2 dissection
- palliative resection
Exclusion Criteria:
- actively bleeding tumor
- perforation of tumor
- patient present with gastric outlet obstruction
- combine organ excision
- known diabetes with nephropathy
- subtotal, D1/D2 dissection
- palliative resection
Exclusion Criteria:
- actively bleeding tumor
- perforation of tumor
- patient present with gastric outlet obstruction
- combine organ excision
- known diabetes with nephropathy
Location
Surgical Ward, Prince of Wales Hospital
Hong Kong, China
Status: Recruiting
Contact: Enders K.W. Ng, MD - 85226322627 - endersng@surgery.cuhk.edu.hk
Start Date
September 2004
Sponsors
Chinese University of Hong Kong
Source
Chinese University of Hong Kong
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
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