The Role of the Vagus Nerve in Tumor-to-Brain Communication in Lung Cancer Patients
Lung Cancer
Conditions: official terms
Lung Neoplasms
Study Type
Study Phase
Study Design
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label
Name: PET/CT imaging
Type: Device
Overall Status
the aim of this study is to measure brain metabolism in patients with lung cancer.FDG uptake in the brain in patients with malignant tumors will be compared to the amount of tracer activity found in patients who have benign pulmonary process. if differences between the brain uptake of FDG in the two groups will be found, further assessment will be performed in order to evaluate if such differences could be attributed and specifically localized to the brain regions innervated by the vagus
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 70 Years
Minimum Age: 35 Years
Gender: Both
Criteria: Inclusion Criteria:

- patients with SPN referred for routine whole body FDG-PET imaging

- patients with NSCLC and patients with no evidence of lung cancer on further follow up

Exclusion Criteria:

- patients with a clinical history of vagotomy, abdominal surgery. brain tumor, brain trauma or CVA. or those with a systemic inflammatory disease
Rambam Medical Center
Haifa, Israel
Status: Recruiting
Contact: Alex Frenkel, Ph.D - 972-4-8543009 -
Start Date
April 2002
Rambam Health Care Campus
Rambam Health Care Campus
Record processing date processed this data on July 28, 2015 page