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Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas
Conditions
Colorectal Neoplasms - Stomach Neoplasms - Pancreatic Neoplasms - Breast Neoplasms - Ovarian Cancer
Conditions: official terms
Breast Neoplasms - Colorectal Neoplasms - Neoplasms - Pancreatic Neoplasms - Stomach Neoplasms
Conditions: Keywords
proteomics of solid tumors
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Natural History, Time Perspective: Longitudinal
Overall Status
Not yet recruiting
Summary
The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response
Detailed Description
The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.
Criteria for eligibility
Healthy Volunteers:
Maximum Age: N/A
Minimum Age: N/A
Gender: Both
Criteria: Inclusion Criteria:
- Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas
Exclusion Criteria:
- Withdrawal of consent
- Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation
- Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas
Exclusion Criteria:
- Withdrawal of consent
- Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation
Location
Hillel Yaffe Medical Center
Hadera, Israel
Status: Not yet recruiting
Contact: Itamar Ashkenazi, M.D. - 972-4-6304761 - i_ashkenazi@yahoo.com
Start Date
February 2007
Sponsors
Hillel Yaffe Medical Center
Source
Hillel Yaffe Medical Center
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page