Procurement of Follicular B Cell Lymphoma Cells for the Purpose of Possible Use in Future Clinical Trials
Non-Hodgkin's Lymphoma
Conditions: official terms
Lymphoma - Lymphoma, B-Cell - Lymphoma, Non-Hodgkin
Conditions: Keywords
Follicular B Cell lymphoma, vaccination
Study Type
Study Phase
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Name: Procurement of Follicular B Cell Lymphoma Cells
Type: Procedure
Overall Status
In order to learn more about follicular lymphoma and anti-cancer vaccines, we are collecting samples from people with this diagnosis. We then hope to make a vaccine from this tissue to help the immune system destroy cancer cells. We plan on keeping samples in the tissue bank indefinitely.
Detailed Description
- The following tests and procedures will be performed: Approximately 50cc of peripheral blood will be drawn and stored in the tissue bank; patients who have follicular lymphoma cells circulating in the blood will have about 40cc's of blood drawn and stored for processing; patients undergoing a lymph node biopsy will have samples of the biopsy stored; patients having fluid drained from the abdomen or from around the lung will have some of their fluid saved to cell collection and processing; patients undergoing a bone marrow biopsy will have some of the sample stored for cell collection and processing.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 35 Years
Gender: Both
Criteria: Inclusion Criteria:

- Relapsed, refractory or de novo histologically confirmed follicular B-cell lymphoma with accessible lymph nodes, tumor mass or malignant effusion or peripheral blood

- 35 years of age or older

Exclusion Criteria:

- Uncontrolled active infection

- HIV or viral Hepatitis infection

- Other current malignancies except any in situ cancer or basal or squamous cell carcinoma of the skin

- Autoimmune cytopenias
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Status: Recruiting
Start Date
June 2007
Completion Date
June 2013
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
Record processing date processed this data on July 28, 2015 page