Endoscopic Mucosal Resection (EMR) in Barrett's Esophagus
Barrett's Esophagus - Early Esophageal Adenocarcinoma
Conditions: official terms
Adenocarcinoma - Barrett Esophagus - Esophageal Neoplasms
Conditions: Keywords
Barrett's Esophagus, Early Esophageal Adenocarcinoma, Endoscopic Mucosal Resection
Study Type
Study Phase
Study Design
Observational Model: Cohort, Time Perspective: Retrospective
Overall Status
Existing records will be reviewed to evaluate the predictors of complications including stricture formation, bleeding or perforation associated with endoscopic mucosal resection
Detailed Description
Barrett's esophagus (BE) is a complication of gastroesophageal reflux disease in which the normal squamous lining of the esophagus is replaced by specialized columnar epithelium.1 Approximately 5%-10% of patients diagnosed with BE are thought to be at risk of developing esophageal adenocarcinoma.2 Patients with high-grade dysplasia (HGD) on biopsy are at the greatest cancer risk³. EMR is being performed clinically in our Barrett's Esophagus Unit on a regular basis during endoscopy for patients with Barrett's Esophagus and/or early esophageal adenocarcinoma. There are two predominant endoscopic mucosal resection (EMR) techniques exist using FDA approved devices - the EMR cap method using a transparent cap/snare combination and the endoscopic variceal ligation method using a band ligator/snare combination to resect tissue.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Barrett's Esophagus Early Esophageal Adenocarcinoma History of Endoscopic Mucosal Resection

Exclusion Criteria:

- NA
Mayo Clinic
Rochester, Minnesota, United States
Status: Recruiting
Contact: Kenneth K Wang, MD - 507-255-7495 - wang.kenneth@mayo.edu
Start Date
October 2007
Completion Date
October 2017
Mayo Clinic
Mayo Clinic
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page