Use of Bone Scintigraphy, CT and MRI in Breast Cancer
Breast Neoplasms
Conditions: official terms
Breast Neoplasms
Conditions: Keywords
SPECT/CT, MRI, Breast neoplasms
Study Type
Study Phase
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Overall Status
A new imaging modality combining CT and tomographic bone scintigraphy (SPECT/CT) has enabled the combination of functional and anatomical imaging. Its use in cancer patients has not yet been evaluated or validated against a relative gold stand or clinical follow up. The purposes of this study are: 1: to validate the use of conventional planar bone scintigraphy and SPECT combined with low-dose or diagnostic CT and compare this to 3 Tesla MRI and clinical follow up. 2: to compare the specificity of low-dose and diagnostic CT, respectively, combined with bone SPECT. 3: to construct an algorithm for optimal evaluation of disease dissemination in breast cancer patients
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 80 Years
Minimum Age: 18 Years
Gender: Female
Criteria: Inclusion Criteria:

- Histological verified breast cancer

- Age 18-80 years

- Investigation for metastases using imaging modality/modalities planned

- Written consent to participate in trial

Exclusion Criteria:

- Overweight limiting the use of MRI

- Metal parts in body

- Claustrophobia

- Allergy to contrast agents used in trial

- Pregnancy
Aarhus University Hospital
Aarhus, Denmark
Status: Recruiting
Start Date
May 2008
Completion Date
March 2011
University of Aarhus
University of Aarhus
Record processing date processed this data on July 28, 2015 page