Permission to Collect Blood Over Time for Research
Conditions
Pancreatic Cancer - Gastrointestinal Neoplasms - Colon Rectal Cancer Adenocarcinoma - Esophageal Cancer - Gall Bladder Cancer - Gastric (Stomach) Cancer - Gastrooesophageal Cancer - Gastrointestinal Stromal Tumor (GIST) - Hepatobiliary Neoplasm - Liver Carcinoma - Gallbladder Carcinoma - Bile Duct Carcinoma - Carcinoma of the Large Intestine - Anal Cancer
Conditions: official terms
Adenocarcinoma - Carcinoma - Carcinoma, Ductal - Carcinoma, Ductal, Breast - Carcinoma, Hepatocellular - Colorectal Neoplasms - Digestive System Neoplasms - Esophageal Neoplasms - Gallbladder Neoplasms - Gastrointestinal Neoplasms - Gastrointestinal Stromal Tumors - Neoplasms - Pancreatic Neoplasms
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Intervention
Name: Observation
Type: Procedure
Overall Status
Recruiting
Summary
To determine whether biomarkers assessed in blood samples can be used to detect individuals at risk for developing blood clots or worsening of their underlying disease. The ultimate goal of the study is to identify key biomarkers derived from blood that are most characteristic and informative of individuals who will go on to develop a clotting complication.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Male or female, >= 18 years old. There are no ethnic restrictions.

- Active cancers of the GI tract (gastroesophageal, colorectal, or pancreatic-biliary) that have completed TNM staging by the American Joint Committee on Cancer; stage III disease if diagnosed within 2 months and all stage IV disease

- Ability to understand and the willingness to sign a written informed consent document.

- Existing staging CT imaging study

Exclusion Criteria:

- Life expectancy < 6 months

- History of deep vein thrombosis (DVT) or pulmonary embolism (PE)

- Known pregnancy or positive urine pregnancy test in pre-menopausal women

- On anticoagulant therapy (heparin, warfarin, direct thrombin inhibitors)

- No CT imaging studies, or contraindications to undergoing CT imaging

- Existing or anticipated need for a tunneled central venous catheter

- Clinic visitation to Stanford Cancer center for secondary consultation purposes only

- Inability to give informed consent
Location
Stanford University School of Medicine
Stanford, California, United States
Status: Recruiting
Contact: Fizaa Ahmed - 650-725-6409 - fizaa@stanford.edu
Start Date
August 2008
Completion Date
December 2015
Sponsors
Stanford University
Source
Stanford University
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page