To hear about similar clinical trials, please enter your email below
Trial Title:
Functional Imaging in HNC Undergoing Chemoradiation
NCT ID:
NCT00837980
Condition:
Head and Neck Cancer
Conditions: Official terms:
Head and Neck Neoplasms
Conditions: Keywords:
head and neck cancer
DW MRI
PET
DCE MRI
functional imaging
IMRT
Study type:
Observational
Overall status:
Unknown status
Study design:
Time perspective:
Prospective
Summary:
The purpose of the study is to generate a library of functional imaging and anatomical
imaging for patients with head and neck cancers for evaluation of new radiotherapy
strategies and planning techniques including IMRT. Secondary aims would be to observe the
changes in the cancers as the treatment progresses as well as to define the biologically
most active part of the tumor (biological target volume) which could be given more
intensive treatment. Tumor volumes seen on different imaging modalities will be compared
with a hope of finding an optimal imaging methodology for accurate visualization of the
head and neck cancers
Detailed description:
Adult patients who have a head and neck cancer and are planned to receive chemotherapy
and radiotherapy will be invited to participate in the study. Patients who are not in
very good health, have diabetes or kidney failure will not be considered for the study.
Also patients who can not undergo MRI scan or are allergic to contrast injection given
prior to the scan or have had any other form of cancer (except skin cancer) will also be
excluded from the study.
Criteria for eligibility:
Study pop:
Adult patients who have a head and neck cancer and are planned to receive chemotherapy
and radiotherapy will be invited to participate in the study. Patients who are not in
very good health, have diabetes or kidney failure will not be considered for the study.
Also patients who can not undergo MRI scan or are allergic to contrast injection given
prior to the scan or have had any other form of cancer (except skin cancer) will also be
excluded from the study.
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- patients with histologically proven head and neck cancer, planed for chemotherapy
and radiotherapy
- age more than 18 years
- patient willing to participate and has signed a consent form
- patients in good physical status (WHO performance status 0-2)
Exclusion Criteria:
- patients in poor health (WHO performance status >2)
- patients with any other cancer apart from skin cancer
- patients with contraindications to MRI scan and IV contrast
- diabetic patients
- patients with renal failure
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
The Royal Marsden NHS Foundation Trust
Address:
City:
Sutton
Zip:
SM6 9QD
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Kate Newbold
Phone:
02086613638
Email:
kate.newbold@rmh.nhs.uk
Contact backup:
Last name:
Prased Dandekar
Phone:
02086613453
Email:
prased.dankekar@rmh.nhs.uk
Investigator:
Last name:
Kate Newbold
Email:
Principal Investigator
Start date:
February 2009
Completion date:
November 2010
Lead sponsor:
Agency:
Royal Marsden NHS Foundation Trust
Agency class:
Other
Source:
Royal Marsden NHS Foundation Trust
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT00837980
