Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis
Cervical Cancer
Conditions: official terms
Uterine Cervical Neoplasms
Conditions: Keywords
Molecular Markers, Cervical Cancer, Screening, Makov
Study Type
Study Phase
Study Design
Observational Model: Case Control, Time Perspective: Prospective
Overall Status
Not yet recruiting
The purpose of this study is to:

1. make p16INK4A as a cervical cancer screening of tumor markers, cytology improve existing diagnostic sensitivity, specificity, repeatability and validity, so as to effectively prompted the early discovery and diagnosis of cervical cancer.

2. reduce screening costs, screening and benefits into quantitative evaluation, for our country to develop cervical cancer prevention and control strategy to provide a reliable theoretical basis.
Detailed Description
1. To carry out large-scale prospective randomized controlled clinical study to evaluate the "cytological molecular markers Detect + P16INK4A" methods of screening accuracy and reliability, as well as the screening method of the biological effects.

2. Markov set up mathematical model of screening tests to quantify the inputs and the evaluation proceeds. With a view to optimize and perfect a simple, convenient, practical and efficient program of cervical cancer screening.
Criteria for eligibility
Healthy Volunteers: Accepts Healthy Volunteers
Maximum Age: 65 Years
Minimum Age: 25 Years
Gender: Female
Criteria: Inclusion Criteria:

- Married women aged 25 to 65-year-old with risk factors

- No tumor and pelvic radiation therapy history

- Non-pregnant women at present
People'S Hospital
Wufeng county, Hubei, China
Start Date
April 2009
Completion Date
July 2011
Wuhan University
Wuhan University
Record processing date processed this data on July 28, 2015 page