Benefit of Roux-en-Y (R-Y) Reconstruction After Pancreaticoduodenectomy
Conditions
Pancreatic Cancer
Conditions: official terms
Pancreatic Neoplasms
Conditions: Keywords
pancreaticoduodenectomy, reconstruction
Study Type
Interventional
Study Phase
N/A
Study Design
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Intervention
Name: R-Y reconstruction
Type: Procedure
Overall Status
Recruiting
Summary
One of the most common complications of pancreaticoduodenectomy (PD) is delayed gastric emptying (DGE), otherwise known as "gastroparesis," which is not fatal but results in prolonged hospital stay and increased hospital costs. Delayed gastric emptying is defined as nasogastric decompression after postoperative day (POD) 10 or a failure to tolerate a regular diet after POD 14. The incidence of DGE has been reported to range from 5% to 72%.
Detailed Description
We hypothesized that the hand-sewn, two-layered, or continuous suture, could induce anastomotic edema to indeed the afferent peristalsis, which is one of the causes of DGE.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 80 Years
Minimum Age: 30 Years
Gender: Both
Criteria: Inclusion Criteria:

- These patients were to undergo elective pancreatic head resection for the treatment of periampullary mass

Exclusion Criteria:

- A body weight loss greater than 10% during the six months prior to surgery

- The presence of distant metastases

- Seriously impaired function of vital organs due to respiratory, renal or heart disease
Location
Kochi Medical School
Nankoku, Kochi, Japan
Status: Recruiting
Contact: Takehiro Okabayashi, MD, PhD - 81-88-880-2370 - tokabaya@kochi-u.ac.jp
Start Date
April 2003
Completion Date
April 2010
Sponsors
Kochi University
Source
Kochi University
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page