Program of Evaluation and Geriatric Intervention on the Functional Status, Quality of the Life, and Survival
Acute Myeloid Leukemia
Conditions: official terms
Leukemia, Myeloid - Leukemia, Myeloid, Acute
Conditions: Keywords
acute myeloid leukemia
Study Type
Study Phase
Study Design
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Name: WITH Comprehensive Geriatric assessment Type: Behavioral
Name: Conventional Type: Behavioral
Overall Status
Acute myeloid leukaemia (AML) is a disease of the elderly, with a median age at diagnosis of 65. A poor outcome in this population has been well established, with very short overall survival (OS) and disease free survival (DFS).There are numerous bad prognostic factors related to the disease itself or to the patient's medical condition.

This study will evaluate the impact of a Comprehensive Geriatric assessment (CGA) performed at diagnosis with planned interventions according to disabilities and monthly follow-up by a nurse practitioner during 6 months on functional status of older cancer patients treated for Acute myeloid leukaemia. Functional status will be assessed with the Lawson Instrumental Activities of Daily Living (IADL) scale at diagnosis and 6 months after randomisation.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 70 Years
Gender: Both
Criteria: Inclusion Criteria:

- Patients aged 70 years and older

- Referred for treatment following a diagnosis of acute myeloid leukaemia.

- signed informed consent

Exclusion Criteria:

- Terminal patients, with a life expectancy estimated to be less than 3 months, will be excluded from the study, due to ethical issues and the fact that they are unlikely to benefit from this evaluation.

- Patients unable to give informed consent.
Marseille, France
Status: Recruiting
Christian RECHER
Toulouse, France
Status: Recruiting
Start Date
March 2010
Institut Paoli-Calmettes
Institut Paoli-Calmettes
Record processing date processed this data on July 28, 2015 page