A Study of Radiation Toxicity in the Liver Using MRI-Based Perfusion
Conditions
Liver Cancer
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Case-Only, Time Perspective: Prospective
Overall Status
Recruiting
Summary
Researchers at the the University of Michigan are conducting a research project to assess how a course of radiation therapy changes the way blood flows through the liver. To be able to do this, the researchers will be using MRI (magnetic resonance imaging) scans completed before, during, and after radiation therapy. MRI's will be done on 4 or 5 occasions. On each occasion, you will be injected with a fluid called gadolinium (a contrast agent) before getting an MRI. This contrast agent makes it easier for the Researchers to see your organs in the scans, and causes any abnormal areas to become very bright on the MRI. This agent will be injected into a vein in your arm or leg. Each MRI scan will last approximately 45 minutes.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Patients must be ≥18 years of age.

- The patient's planned cancer management is radiation to the liver with or without chemotherapy.

- Patients must have a performance status of 0-2 and a life expectancy of at least 3 months.

- Patients should have no contraindications to having a contrast enhanced MRI scan.

Exclusion Criteria:

- Women who are pregnant or breastfeeding are excluded.

- Prisoners are excluded
Location
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States
Status: Recruiting
Contact: Mary Feng, MD - 734-936-4288 - maryfeng@med.umich.edu
Start Date
November 2006
Completion Date
January 2016
Sponsors
University of Michigan Cancer Center
Source
University of Michigan Cancer Center
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page