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Trial Title:
Clinical Study in Post-operation Treatment of Cervical Cancer
NCT ID:
NCT01418859
Condition:
Cervical Cancer
Conditions: Official terms:
Uterine Cervical Neoplasms
Conditions: Keywords:
cervical cancer
postoperation
chemotherapy
radiotherapy
Study type:
Observational
Overall status:
Unknown status
Study design:
Time perspective:
Prospective
Summary:
The purpose of the research is to evaluate the effect of additional chemotherapy in
postoperation therapy of cervical cancer patients with risk factors (big tumor, deep
invasion or tumor thrombi in the vascular system).
Detailed description:
Cervical cancer has a very high morbidity. Many patients need additional therapy after
surgery in order to elevate the survival rate and life quality. In this research, we are
going to give additional therapy to patients who have big tumor, deep invasion or tumor
thrombi in the vascular system after surgery. randomized control method will be used in
this research, in order to compare the survival rate and side effects between radiation
therapy only, concurrent chemoradiotherapy, and concurrent chemoradiotherapy with
additional chemotherapy. 3D-CRT and Topotecan will be used in this research.
Criteria for eligibility:
Study pop:
patients who underwent the cervical cancer radical surgery in three months have higt risk
factors which including deep stromal invasion,large primary tumour and/or lymphovascular
spase invasion.
Sampling method:
Probability Sample
Criteria:
Inclusion Criteria:
1. patients who underwent the cervical cancer radical surgery in three months have higt
risk factors which including deep stromal invasion,large primary tumour and/or
lymphovascular spase invasion;
2. squamous carcinoma;
3. age<70;
4. Gynecologic Oncology Group (GOG):0-2.
Exclusion Criteria:
1. negative nodes,surgical margin,and/or parametrium;
2. No serious damage to the liver and kidney function, no hypertension,diabetes and
other effects of therapy complications.
Gender:
Female
Minimum age:
20 Years
Maximum age:
70 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
Xi'an Jiaotong University College of Medicine
Address:
City:
Xi'an
Zip:
710061
Country:
China
Status:
Recruiting
Contact:
Last name:
Zi Liu, M.D
Phone:
086-18991232167
Email:
18991232167@189.cn
Contact backup:
Last name:
Tao Wang, M.D
Phone:
086-18991232386
Email:
18991232386@189.cn
Investigator:
Last name:
Tao Wang, M.D
Email:
Sub-Investigator
Start date:
August 2011
Completion date:
December 2015
Lead sponsor:
Agency:
Health Science Center of Xi'an Jiaotong University
Agency class:
Other
Source:
Health Science Center of Xi'an Jiaotong University
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT01418859
