A Prospective and Observational Cohort Study to Evaluate the Treatment Model and Medical Economics of Advanced Gastric Cancer Chemotherapy in Clinical Practice in China
Conditions
Advanced Gastric Cancer
Conditions: official terms
Stomach Neoplasms
Conditions: Keywords
Advanced Gastric Cancer, chemotherapy, quality of life, treatment expense, patients accepted first-line chemotherapy
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Intervention
Name: Clinical chemo-drugs
Type: Drug
Overall Status
Recruiting
Summary
This is a multi-center, prospective and observational clinical study. Eligible patients will accept generalized chemotherapy according to the investigator's assessment. Information related to the treatment, including medication, disease condition, expenses, etc. will be periodically collected. Follow-up at 2-month intervals will be periodically performed to continually collect information about the disease progression, subsequent treatment and survival until death or completion of the study.

Recruited patients will fill out questionnaires about quality of life before initiation of treatment, at Cycle 3 and completion of first-line treatment.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 85 Years
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

1. The patient has histologically confirmed locally-advanced or recurrent and/or metastatic gastric or esophagogastric junction adenocarcinoma, has missed the opportunity of surgical excision, making curative therapy impossible.

2. The informed consent form is signed.

3. A specimen of tumor tissue (puncture biopsy or surgical specimen) is available.

4. ECOG performance status is 0, 1 or 2.

5. The patient's general conditions and functions of important organs allow generalized chemotherapy according to the investigator's judgment

6. The patient is aged≥18

Exclusion Criteria:

1. The patient is known to be allergic to any study drug.

2. The patient is recruited in other clinical study or is planned to participate into other clinical study.

3. The patient has previously accepted chemotherapy against advanced or metastatic diseases (the patient may be recruited if the previous adjuvant therapy/neoadjuvant therapy was completed more than 6 months before inclusion).
Location
Lin Shen
Beijing, Beijing, China
Status: Recruiting
Contact: lin shen, MD - 861088196561 - lin100@medmail.com.cn
Start Date
November 2011
Completion Date
February 2016
Sponsors
Peking University
Source
Peking University
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page