Autologous CIK Cells Infusion for the Treatment of Lung Cancer: a Randomized Controlled Study
Conditions
Lung Cancer
Conditions: official terms
Lung Neoplasms
Conditions: Keywords
lung cancer, CIK cells, therapy
Study Type
Observational
Study Phase
Phase 2/Phase 3
Study Design
Observational Model: Case Control, Time Perspective: Prospective
Overall Status
Recruiting
Summary
To study the efficacy and safety of autologous CIK cells infusion for the treatment of lung cancer.
Detailed Description
A randomized controlled trail on the efficacy and safety of autologous cytokine-induced killer (CIK) cells infusion treatment in advanced primary lung cancer
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 70 Years
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- 18~70 year old, KPS score >50 points, estimate survival > 3 months;

- Primary lung cancer patients after chemotherapy or radiation therapy;

- Primary lung cancer patients after targeted therapy;

- Primary lung cancer patients with lung function can not accept operation or unwilling to operation;

- Primary lung cancer recurrence or surgery can't complete resection;

- Primary lung cancer patients after intervention therapy(I125 implanted, freezing, rf, etc.);

- No serious mental illness and no serious heart, liver, kidney diseases, unincorporated other potentially lethal diseases;

- Patients Voluntary attempt, and informed consent.

Exclusion Criteria:

- History of cardiovascular disease: congestive heart failure > New York heart association (NYHA) level II, unstable angina patients (resting when the angina symptoms) or new happen angina pectoris (recent 3 months) or recent 6 months of myocardial infarction;

- Cachexia; or other deadly diseases;

- Liver function laboratory ALT, AST more than normal limits on 2.0 times ; Or kidney TBIL, BUN more than normal limits on 1.0 times , or Cr more than normal upper limit;

- Active infection;

- Pregnant or lactating women

- At present Is receiving other cancer treatment (such as chemotherapy, radiation therapy, chemotherapy, immunosuppressants and thrombosis, targeted agents);

- Now or recently will join another experimental clinical study ;

- Other situations that the researchers considered unsuitable for this study (such as mental illness, drug abuse, HIV infections, etc.), or influence on the results of clinical trials for analysis.
Location
Liang Gong
Chong Qing, Chong Qing, China
Status: Recruiting
Contact: Liang Gong - 13983965893 - gonglw1@gmail.com
Start Date
December 2011
Completion Date
December 2013
Sponsors
Third Military Medical University
Source
Third Military Medical University
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page