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Radiofrequency Ablation in Thyroid Nodules
Conditions
Thyroid Nodules
Conditions: official terms
Thyroid Diseases - Thyroid Nodule
Conditions: Keywords
radiofrequency, thyroid, nodule
Study Type
Interventional
Study Phase
N/A
Study Design
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Intervention
Name: Radiofrequency ablation of the thyroid nodule
Type: Procedure
Overall Status
Recruiting
Summary
Thyroid nodules are common problems and although > 95% are stated to be benign, they may cause some problems like hyperthyroidism, compression symptoms, and cosmesis associated with their function, size and localization. Especially for these nodules, patients undergo surgery and face up with the problems associated with surgical complications although they are not cancer. In some studies, radiofrequency ablation previously used for intrabdominal tumors like hepatic metastasis...,was stated to be efficient in the treatment of benign thyroid nodules and in some recurrent thyroid cancer cases. Therefore, the investigators decided to use this method in our patients having nodules like previously mentioned and see the efficacy and safety of the technique.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: 70 Years
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:
1. the presence of subjective symptoms (foreign body sensation, neck discomfort or pain, compressive symptom) or cosmetic problems;
2. a poor surgical candidate or refusal to undergo surgery;
3. fine-needle aspiration cytology and US findings that were compatible with a benign nodule;
4. anxiety about a malignancy.
Exclusion Criteria:
1. a nodule less than 5 mm in size;
2. follicular neoplasm or malignancy on fine needle aspiration cytology (FNAC);
3. a nodule with the sonographic criteria for a malignancy (taller than wide, marked hypoechoic, microcalcifications, ill-defined margins), although FNAC was a benign result;
4. previous radiation or operation history to the head and neck; (5) previous sclerosing therapy.
1. the presence of subjective symptoms (foreign body sensation, neck discomfort or pain, compressive symptom) or cosmetic problems;
2. a poor surgical candidate or refusal to undergo surgery;
3. fine-needle aspiration cytology and US findings that were compatible with a benign nodule;
4. anxiety about a malignancy.
Exclusion Criteria:
1. a nodule less than 5 mm in size;
2. follicular neoplasm or malignancy on fine needle aspiration cytology (FNAC);
3. a nodule with the sonographic criteria for a malignancy (taller than wide, marked hypoechoic, microcalcifications, ill-defined margins), although FNAC was a benign result;
4. previous radiation or operation history to the head and neck; (5) previous sclerosing therapy.
Locations
Bezmialem Vakif University
Istanbul, Turkey
Bezmialem Vakif University
Status: Recruiting
Contact: Erhan Aysan, Prof - 902124531700 - erhanaysan@hotmail.com
Istanbul, Turkey
Bezmialem Vakif University medical Faculty
Status: Recruiting
Contact: ERHAN AYSAN, PROF. - 902124531700 - yelizemineersoy@yahoo.com
Istanbul, Turkey
Status: Recruiting
Contact: Erhan Aysan, Prof. Dr. - erhanaysan@hotmail.com
Start Date
April 2013
Completion Date
June 2014
Sponsors
Bezmialem Vakif University
Source
Bezmialem Vakif University
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page