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Trial Title:
Establishment of a Tumor Bank for Tissue Samples
NCT ID:
NCT01789229
Condition:
Ovarian Neoplasms
Breast Neoplasms
Colorectal Neoplasms
Neoplasms of the Female Genitalia
Lung Neoplasms
Endocrine Gland Neoplasms
Conditions: Official terms:
Neoplasms
Breast Neoplasms
Colorectal Neoplasms
Lung Neoplasms
Ovarian Neoplasms
Endocrine Gland Neoplasms
Conditions: Keywords:
biobank
fresh-frozen tissue
Study type:
Observational
Overall status:
Recruiting
Study design:
Time perspective:
Other
Intervention:
Intervention type:
Other
Intervention name:
Tumor tissue collection
Description:
Tissue sample is collected during therapeutic intervention by a medical doctor/surgeon.
Frozen tissue sections are first transferred to Dept.of Pathology. Pathologist samples
required tissue to obtain enough evidence for analysis/diagnosis.
Rest tumor material with or without malignant cells is tranferred to the lab for
Molecular Oncology of Prof.Zeillinger.
Arm group label:
Benign controls
Arm group label:
Malignant tumors
Intervention type:
Other
Intervention name:
Sampling of ascites and pleural effusion
Description:
Samples of malignant ascites and/or malignant pleural effusion is only collected during
therapeutic intervention from patients at inpatient care.
Arm group label:
Benign controls
Arm group label:
Malignant tumors
Intervention type:
Other
Intervention name:
Collecting urine samples
Description:
Patient is asked to give a urine sample. Urine is collected in urine beaker.
Arm group label:
Benign controls
Arm group label:
Healthy controls
Arm group label:
Malignant tumors
Intervention type:
Other
Intervention name:
Collecting saliva sample
Description:
Saliva sample is collected by spatula from the mouth cavity of the patient.
Arm group label:
Benign controls
Arm group label:
Healthy controls
Arm group label:
Malignant tumors
Intervention type:
Other
Intervention name:
Collecting sputum
Description:
Patient is asked to produce sputum into a 50ml lab tube.
Arm group label:
Benign controls
Arm group label:
Healthy controls
Arm group label:
Malignant tumors
Intervention type:
Other
Intervention name:
Collecting stool samples
Description:
Stool samples are collected prior to bowel preparation for colonoscopy. Device for
sampling is provided to the patient.
Arm group label:
Benign controls
Arm group label:
Healthy controls
Arm group label:
Malignant tumors
Intervention type:
Other
Intervention name:
Lavage/Irrigation
Description:
Irrigation liquid is collected during routine therapeutic or diagnostic procedure, e.g.
lavage of the uterine cavity and fallopian tubes of women scheduled for surgery.
Arm group label:
Benign controls
Arm group label:
Healthy controls
Arm group label:
Malignant tumors
Summary:
Establishment of a tumor bank, consisting of tissue samples of tumor patients (benign and
malign tumors) and healthy people as controls. The tissue samples will be collected
systematically together with the corresponding clinical data. The biological samples, the
clinical date together with prospective experimental date constitute the entity of the
tissue tumor bank.
This tumor bank for tissue samples, together with our tumorbank for blood samples
(NCT01763125) combined constitute the entity "Tumorbank".
Detailed description:
Recent progress in diagnosis and therapy of cancer diseases can be ascribed mainly to
translational research. The relevance of "translational oncology" will only increase in
the future -"From bench to bedside" - the swift implementation of new science research
results in clinical studies in order to expedite progress in clinical cancer therapy for
the benefit of the patient.
Its almost a matter of course in the medical science today to collect biological samples
together with clinical information thereby creating the foundation for future excellent
fundamental research.
The aim of this tumor bank is to consist of biological samples (together with a blood
bank - see NCT01763125) and isolates of tumor patients and healthy people as controls.
The biological samples, the clinical date together with prospective experimental date
constitute the entity of the tumor bank. The content of the tumor bank can provide
essential material for current and future research (e.g. analyses of prognostic or
predictive tumor markers; genetically analysis (polymorphism, mutation, hypermethylation;
verification and characterisation of disseminated tumor cells).
Criteria for eligibility:
Study pop:
Male and female patients/people. Minimum age 18 years Characteristics: Recruited at the
Medical University Vienna or at one of the facilities cooperating with the Vienna Med.
University
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Male/Female
- Age 18 to 90 years max.
- Just one current known malignant disease or just one current inflammatory disease
Exclusion Criteria:
- Inflammatory disease and malignant disease
- multiple malignancies
- multiple diseases
- underage
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
Accepts Healthy Volunteers
Locations:
Facility:
Name:
Medical University Vienna, Dptm. of Obstetrics & Gynaecology
Address:
City:
Vienna
Zip:
1090
Country:
Austria
Status:
Recruiting
Contact:
Last name:
Christoph Grimm, assoc. Prof., MD
Email:
christoph.grimm@muv.ac.at
Contact backup:
Last name:
Stephan Polterauer, assoc. Prof., MD
Email:
stephan.polterauer@muv.ac.at
Facility:
Name:
University Hospitals Leuven - Department of Obstetrics and Gynaecology
Address:
City:
Leuven
Zip:
3000
Country:
Belgium
Status:
Completed
Facility:
Name:
Charité University - Campus Virchow Chlinic
Address:
City:
Berlin
Zip:
13353
Country:
Germany
Status:
Active, not recruiting
Start date:
September 2003
Completion date:
December 2026
Lead sponsor:
Agency:
Medical University of Vienna
Agency class:
Other
Source:
Medical University of Vienna
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT01789229
