Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness
Conditions
Rectal Diseases - Rectal Neoplasms - Gastrointestinal Diseases - Gastrointestinal Neoplasms
Conditions: official terms
Aggression - Digestive System Diseases - Digestive System Neoplasms - Gastrointestinal Diseases - Gastrointestinal Neoplasms - Neoplasms - Rectal Diseases - Rectal Neoplasms
Conditions: Keywords
Magnetic Resonance Imaging, Magnetic Resonance Imaging, Functional
Study Type
Observational
Study Phase
N/A
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Intervention
Name: new functional magnetic resonance imaging (MRI) protocols
Type: Procedure
Overall Status
Recruiting
Summary
The purpose of this study is to establish a reliable method for detection of rectal cancer patients with aggressive tumor at risk of metastatic disease and death by functional MRI.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- The patient is willing and able to give full written consent according to the protocol approved by the Regional Ethics Committee.

- The patient has confirmed rectal cancer diagnosis and is scheduled to radical surgery alone or preoperative CRT followed by surgery.

- The patient is ≥ 18 years.

- The patient has no prior rectal cancer treatment.

- The patient has adequate renal function: creatinine clearance ≥ 60 ml/minute.

- The patient has signed the written informed consent according to the protocol approved by the Regional Ethics Committee.

Exclusion Criteria:

- The patient has contraindication to MRI or MRI contrast agent according to clinical practice.

- The patient wants to withdraw for any reason during the study.
Location
Akershus University Hospital
Lørenskog, Akershus, Norway
Status: Recruiting
Contact: Kathrine Røe, PhD - +4792437646 - kathrine.roe@medisin.uio.no
Start Date
October 2013
Completion Date
June 2016
Sponsors
University Hospital, Akershus
Source
University Hospital, Akershus
Record processing date
ClinicalTrials.gov processed this data on July 28, 2015
ClinicalTrials.gov page