The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer
Thyroid Cancer
Conditions: official terms
Thyroid Diseases - Thyroid Neoplasms
Conditions: Keywords
thyroid cancer, radioiodine treatment, xerostomia, sialadenitis
Study Type
Study Phase
Study Design
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Single Blind (Investigator), Primary Purpose: Prevention
Name: thymus honey mouthwash
Type: Dietary Supplement
Overall Status
The purpose of this study is to determine whether the use of honey mouthwashes in the prevention of salivary side effects of 131I (radioiodine) therapy.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: N/A
Gender: Both
Criteria: Inclusion Criteria:

- >18 years old

- They had a histological diagnosis of papillary, follicular, medullary or anaplastic thyroid cancer

- They had undergone total thyroidectomy

- They were able to provide consent

Exclusion Criteria:

- patients who had distant metastases,

- a history of salivary-gland disorders,

- collagen tissue disease

- diabetes mellitus,

- previous radioiodine therapy or external radiation to the head or neck

- allergy to the honey
Bank of Cyprus Oncology
Nicosia, Cyprus
Status: Recruiting
Start Date
May 2013
Completion Date
September 2015
Cyprus University of Technology
Cyprus University of Technology
Record processing date processed this data on July 28, 2015 page