Thromboelastography During Surgery for Malignant Pleural Mesothelioma
Coagulopathy - Mesothelioma
Conditions: official terms
Blood Coagulation Disorders - Hemostatic Disorders - Mesothelioma
Study Type
Study Phase
Phase 0
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Name: Blood draw for TEG analysis
Type: Procedure
Overall Status
Surgery for malignant pleural mesothelioma is complex and prolonged, and may involve significant blood loss with considerable blood and product transfusion. Thromboelastography (TEG) is a global assay of coagulation that uses whole blood to produce a tracing that records kinetic changes in clot formation. This study aims provide a better understanding of the coagulation profile of these patients, and will form the basis of a TEG-based transfusion algorithm for future surgeries for mesothelioma.
Detailed Description
Thromboelastography can provide more in-depth and quicker analysis of the complex coagulation processes during surgery
Criteria for eligibility
Healthy Volunteers: Accepts Healthy Volunteers
Maximum Age: N/A
Minimum Age: 18 Years
Gender: Both
Criteria: Inclusion Criteria:

- Adult male or female patients undergoing elective surgery for malignant pleural mesothelioma

Exclusion Criteria:

- Unwilling or unable to provide consent

- History of bleeding disorder

- On medications that may affect hemostasis
Brigham and Women's Hospital
Boston, Massachusetts, United States
Status: Recruiting
Contact: Ju-Mei Ng, MD - 617-732-8219 -
Start Date
September 2013
Completion Date
December 2015
Brigham and Women's Hospital
Brigham and Women's Hospital
Record processing date processed this data on July 28, 2015 page