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Trial Title:
The Effect of Different Doses of Remifentanil on Kidney Function During Robot Assisted Prostatectomy - A Retrospective Study
NCT ID:
NCT02041559
Condition:
Prostate Cancer
Conditions: Official terms:
Prostatic Neoplasms
Study type:
Observational
Overall status:
Unknown status
Study design:
Time perspective:
Retrospective
Summary:
Robot assisted prostatectomy reduces the patients' postoperative pain and leads to rapid
rehabilitation. But pneumoperitoneum affects the kidney. The increase of stress hormone
reduces the glomerular filtration and the vaso-contraction of renal vessels leads the
renal ischemia. Remifentanil is analgesics coupled with μ opioid receptor. In high dose
of remifentanil, it is associated with κ and δ receptors, which leads to renal protection
effect in animal study. Also, remifentanil infusion during anesthesia showed a diuretic
effect. The purpose of this study is to investigate the remifentanil effect on renal
function during robot assisted prostatectomy.
Criteria for eligibility:
Study pop:
male patients undergoing robot assisted prostatectomy
Sampling method:
Probability Sample
Criteria:
Inclusion Criteria:
- ages > 19 years and < 85 years
- the patients undergoing a general anesthesia for robot assisted prostatectomy
Exclusion Criteria:
- incomplete record
- history of opioid or steroid using
- solitary kidney
- history of kidney transplantation
Gender:
Male
Minimum age:
20 Years
Maximum age:
85 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University Health System
Address:
City:
Seoul
Zip:
120-752
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Ji Eun Kim, MD
Phone:
82-2-2019-6808
Email:
beye98@yuhs.ac
Start date:
January 2014
Completion date:
December 2014
Lead sponsor:
Agency:
Yonsei University
Agency class:
Other
Source:
Yonsei University
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT02041559
