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Trial Title:
Portal Hypertension and Liver Resection in Patients With Hepatocellular Carcinoma
NCT ID:
NCT02145013
Condition:
Primary Liver Cancers
Conditions: Official terms:
Carcinoma
Carcinoma, Hepatocellular
Hypertension, Portal
Hypertension
Conditions: Keywords:
portal hypertension, hepatocellular carcinoma, resection
Study type:
Observational
Overall status:
Unknown status
Study design:
Time perspective:
Prospective
Intervention:
Intervention type:
Procedure
Intervention name:
Liver resection
Description:
Hepatectomy by either open, laparoscopic or robotic procedures
Arm group label:
No portal hypertension
Arm group label:
Portal hypertension
Summary:
According to the BCLC guidelines, surgical resection of hepatocellular carcinoma complicating
cirrhosis is restricted to patients with preserved liver function, single nodule without
vascular invasion and with hepatic venous gradient below 10 mmHg.
However, other guideline treatment, especially from eastern countries demonstrated that
surgical resection is safe and feasible and provides better survival than the treatment
recommended by the BCLC system for patients with similar stage.
The primary goal of this study is to assess the impact of HVPG on short and long-term
outcomes in HCC patients who undergo liver resection.
Detailed description:
Patients with HCC and candidates for hepatectomy are classified into two groups according to
the presence of portal hypertension. Short- and long-term outcomes will be compared.
Criteria for eligibility:
Study pop:
All patients with hepatocellular carcinoma
Sampling method:
Probability Sample
Criteria:
Patients with hepatocellular carcinoma who undergo surgical resection (intention to treat
analysis)
Gender:
All
Minimum age:
N/A
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Henri Mondor University Hospital
Address:
City:
Creteil
Zip:
94000
Country:
France
Start date:
November 2013
Completion date:
May 30, 2018
Lead sponsor:
Agency:
Henri Mondor University Hospital
Agency class:
Other
Source:
Henri Mondor University Hospital
Record processing date:
ClinicalTrials.gov processed this data on April 10, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT02145013
