Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors
Germ Cell Cancer
Conditions: official terms
Neoplasms, Germ Cell and Embryonal - Testicular Neoplasms
Conditions: Keywords
Germ cell cancer, Late toxicity, Renal impairment, Cardiovascular disease
Study Type
Study Phase
Study Design
Observational Model: Cohort, Time Perspective: Retrospective
Overall Status
The purpose of this study is to identify genetic variations in survivors of testicular cancer and connect these variations to differences in risks of late effects.
Detailed Description
Identification of late-effects through questionnaires and linkage to national registries. DNA samples will be gathered through buccal swabs or saliva kits and analysed with whole exome-sequencing.
Criteria for eligibility
Healthy Volunteers: No
Maximum Age: N/A
Minimum Age: 15 Years
Gender: Male
Criteria: Inclusion Criteria:

- Danish citizen

- Diagnosed with germ cell cancer from 1984 to 2007

- Treated initially at a Danish hospital

- Treated with standard treatment regimens.

Exclusion Criteria:

- Treated initially at a foreign hospital
Dept. of Oncology, Rigshospitalet
Copenhagen, Denmark
Status: Recruiting
Start Date
August 2014
Completion Date
January 2016
Rigshospitalet, Denmark
Rigshospitalet, Denmark
Record processing date processed this data on July 28, 2015 page