Trial Title:
A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
NCT ID:
NCT05221840
Condition:
Non-Small Cell Lung Cancer
Conditions: Official terms:
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Durvalumab
Conditions: Keywords:
Non-Small Cell Lung Cancer
Locally Advanced NSCLC
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Masking description:
Double-Blind
Intervention:
Intervention type:
Drug
Intervention name:
Durvalumab
Description:
Durvalumab IV (intravenous infusion)
Arm group label:
Arm A: Durvalumab and Oleclumab
Arm group label:
Arm B: Durvalumab and Monalizumab
Arm group label:
Arm C: Durvalumab and Placebo
Intervention type:
Drug
Intervention name:
Oleclumab
Description:
Oleclumab IV (intravenous infusion)
Arm group label:
Arm A: Durvalumab and Oleclumab
Intervention type:
Drug
Intervention name:
Monalizumab
Description:
Monalizumab IV (intravenous infusion)
Arm group label:
Arm B: Durvalumab and Monalizumab
Intervention type:
Other
Intervention name:
Placebo
Description:
Placebo IV (intravenous infusion)
Arm group label:
Arm B: Durvalumab and Monalizumab
Arm group label:
Arm C: Durvalumab and Placebo
Summary:
This is a Phase III, randomised, double-blind, multicentre, international study assessing
the efficacy and safety of durvalumab (MEDI4736) in combination with oleclumab (MEDI9447)
or durvalumab (MEDI4736) with monalizumab (IPH2201) in adults with locally advanced
(Stage III), unresectable NSCLC, who have not progressed following platinum-based cCRT.
Criteria for eligibility:
Criteria:
INCLUSION CRITERIA:
- Participant must be ≥ 18 years at the time of screening.
- Histologically- or cytologically-documented NSCLC and have been treated with
concurrent CRT for locally advanced, unresectable (Stage III) disease
- Provision of a tumour tissue sample obtained prior to CRT
- Documented tumour PD-L1 status by central lab
- Documented EGFR and ALK wild-type status (local or central).
- Patients must not have progressed following definitive, platinum based, concurrent
chemoradiotherapy
- Participants must have received at least 2 cycles of platinum-based chemotherapy
concurrent with radiation therapy
- Participants must have received a total dose of radiation of 60 Gy ±10% (54 Gy to 66
Gy) as part of the chemoradiation therapy, to be randomised. Radiation therapy
should be administered by intensity modulated RT (preferred) or 3D-conforming
technique.
- WHO performance status of 0 or 1 at randomization
- Adequate organ and marrow function
EXCLUSION CRITERIA:
- History of another primary malignancy except for malignancy treated with curative
intent with no known active disease ≥5 years before the first dose of study
intervention and of low potential risk for recurrence, adequately resected
non-melanoma skin cancer and curatively treated in situ disease, or adequately
treated carcinoma in situ or Ta tumours without evidence of disease.
- Mixed small cell and non-small cell lung cancer histology.
- Participants who receive sequential (not inclusive of induction) chemoradiation
therapy for locally advanced (Stage III) unresectable NSCLC.
- Participants with locally advanced (Stage III) unresectable NSCLC who have
progressed during platinum-based cCRT.
- Any unresolved toxicity CTCAE >Grade 2 from the prior chemoradiation therapy
(excluding alopecia).
- Participants with ≥grade 2 pneumonitis from prior chemoradiation therapy.
- History of idiopathic pulmonary fibrosis, drug-induced pneumonitis, or idiopathic
pneumonitis - regardless of time of onset prior to randomisation. Evidence of active
non-CRT induced pneumonitis (≥ Grade 2), active pneumonia, active ILD, active or
recently treated pleural effusion, or current pulmonary fibrosis - diagnosed in the
past 6 months prior to randomization.
- Active or prior documented autoimmune or inflammatory disorders (with exceptions)
- Current or prior use of immunosuppressive medication within 14 days before the first
dose of durvalumab.
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Research Site
Address:
City:
San Diego
Zip:
92123
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
New Haven
Zip:
06510
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Stuart
Zip:
34994
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Urbana
Zip:
61801
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
New Albany
Zip:
47150
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Waterloo
Zip:
50703
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Lexington
Zip:
40503
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Louisville
Zip:
40241
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Scarborough
Zip:
04074
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Annapolis
Zip:
21401
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Baltimore
Zip:
21201
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Baltimore
Zip:
21229
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bethesda
Zip:
20817
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Grand Rapids
Zip:
49503
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Duluth
Zip:
55805
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Duluth
Zip:
55812
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Billings
Zip:
59101
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Ridgewood
Zip:
07450
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Ithaca
Zip:
14850
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Middletown
Zip:
10941
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Greensboro
Zip:
27403
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Cleveland
Zip:
44111
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Cleveland
Zip:
44124
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Cleveland
Zip:
44195
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Independence
Zip:
44131
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Maumee
Zip:
43537
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Portland
Zip:
97239
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Philadelphia
Zip:
19104
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
York
Zip:
17403
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Sioux Falls
Zip:
57105
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Memphis
Zip:
38120
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Suspended
Facility:
Name:
Research Site
Address:
City:
Charlottesville
Zip:
22908
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Fairfax
Zip:
22031
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Fredericksburg
Zip:
22408
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Richmond
Zip:
23235
Country:
United States
Status:
Terminated
Facility:
Name:
Research Site
Address:
City:
Richland
Zip:
99352
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Spokane
Zip:
99204
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Tacoma
Zip:
98405
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Milwaukee
Zip:
53226
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Box Hill
Zip:
3128
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
East Melbourne
Zip:
3002
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Elizabeth Vale
Zip:
5112
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Gosford
Zip:
2250
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Heidelberg
Zip:
3084
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Kogarah
Zip:
2217
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
South Brisbane
Zip:
4101
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
St Albans
Zip:
3021
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
St. Leonards
Zip:
2065
Country:
Australia
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Westmead
Zip:
2145
Country:
Australia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Barretos
Zip:
14784-400
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Belo Horizonte
Zip:
30380-090
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Florianópolis
Zip:
88034-000
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Fortaleza
Zip:
60336-232
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Jaú
Zip:
17210-120
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Natal
Zip:
59075-740
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Porto Alegre
Zip:
90610-001
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Porto Alegre
Zip:
91350-200
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Recife
Zip:
52010-075
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Sao Paulo
Zip:
01323-903
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Uberlândia
Zip:
38408-150
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Vitoria
Zip:
29043-260
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Edmonton
Zip:
T6G 1Z2
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Barrie
Zip:
L4M 6M2
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hamilton
Zip:
L8V 5C2
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Kingston
Zip:
K7L 2V7
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
London
Zip:
N6A 5W9
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Mississauga
Zip:
L5M 2N1
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Toronto
Zip:
M5G 2M9
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Rimouski
Zip:
G5L 5T1
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Anyang
Zip:
455000
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Beijing
Zip:
100021
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Beijing
Country:
China
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Changchun
Zip:
130021
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Changsha
Zip:
410008
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Changsha
Zip:
410013
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Chongqing
Zip:
400010
Country:
China
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Guangzhou
Zip:
510060
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Guangzhou
Zip:
510062
Country:
China
Status:
Terminated
Facility:
Name:
Research Site
Address:
City:
Guangzhou
Zip:
510700
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Hangzhou
Zip:
310002
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Hangzhou
Zip:
310022
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hefei
Zip:
133500
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Hefei
Zip:
230031
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Jieyang
Zip:
522000
Country:
China
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Kunming
Zip:
650118
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Linhai
Zip:
317000
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Nanning
Zip:
530021
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Nantong
Zip:
226361
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Neijiang
Zip:
641000
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Ningbo
Zip:
315100
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Shanghai
Zip:
200433
Country:
China
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Shaoguan
Zip:
512027
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Shenyang
Zip:
110042
Country:
China
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Tianjin
Zip:
300060
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Wuhan
Zip:
430022
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Wuhan
Zip:
430071
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Wuhan
Zip:
430079
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Zhanjiang
Zip:
524001
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Zhengzhou City
Zip:
450000
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Research Site
Address:
City:
Zhengzhou
Zip:
450008
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Zhongshan
Zip:
528403
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Zhuhai
Zip:
519000
Country:
China
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Barranquilla
Zip:
080012
Country:
Colombia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Barranquilla
Zip:
080020
Country:
Colombia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bogota D.C.
Zip:
110131
Country:
Colombia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bogotá
Country:
Colombia
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Medellin
Zip:
050034
Country:
Colombia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Valledupar
Zip:
200001
Country:
Colombia
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Avignon Cedex 9
Zip:
84918
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Besançon Cedex
Zip:
25030
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bordeaux
Zip:
33075
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Clermont-Ferrand
Zip:
63000
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Creteil Cedex
Zip:
94010
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lorient cedex
Zip:
56322
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Marseille Cedex 20
Zip:
13015
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Montpellier
Zip:
34298
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Paris Cedex 5
Zip:
75005
Country:
France
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Rennes
Zip:
35033
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Rouen
Zip:
76031
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Toulouse CEDEX 09
Zip:
31059
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Villejuif Cedex
Zip:
94805
Country:
France
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Erfurt
Zip:
99089
Country:
Germany
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Erlangen
Zip:
91054
Country:
Germany
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Essen
Zip:
45147
Country:
Germany
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Esslingen
Zip:
73730
Country:
Germany
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Georgsmarienhuette
Zip:
49124
Country:
Germany
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Guetersloh
Zip:
33332
Country:
Germany
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hannover
Zip:
30459
Country:
Germany
Status:
Terminated
Facility:
Name:
Research Site
Address:
City:
Oldenburg
Zip:
26121
Country:
Germany
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Würzburg
Zip:
97080
Country:
Germany
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Brescia
Zip:
25123
Country:
Italy
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Firenze
Zip:
50134
Country:
Italy
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lucca
Zip:
55100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Meldola
Zip:
47014
Country:
Italy
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Orbassano
Zip:
10043
Country:
Italy
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Parma
Zip:
43126
Country:
Italy
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Pavia
Zip:
27100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Roma
Zip:
00128
Country:
Italy
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Himeji-shi
Zip:
670-8520
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hiroshima-shi
Zip:
730-0011
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Kashiwa
Zip:
227-8577
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Kurume-shi
Zip:
830-0011
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Natori-shi
Zip:
981-1293
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Niigata-shi
Zip:
951-8566
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Osaka-shi
Zip:
541-8567
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Sendai-shi
Zip:
980-0873
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Tokushima-shi
Zip:
770-8503
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Toon-shi
Zip:
791-0295
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Wakayama-shi
Zip:
641-8510
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Changwon-si
Zip:
51353
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Cheongju-si
Zip:
28644
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Seongnam-si
Zip:
13620
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Seoul
Zip:
03080
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Seoul
Zip:
03722
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Seoul
Zip:
05505
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Suwon-si
Zip:
16499
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Suwon
Zip:
16247
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Arequipa
Zip:
04000
Country:
Peru
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Concepción
Zip:
12125
Country:
Peru
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lima
Zip:
15036
Country:
Peru
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Lima
Zip:
15036
Country:
Peru
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Lima
Zip:
15038
Country:
Peru
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lima
Zip:
LIMA 11
Country:
Peru
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Lima
Zip:
LIMA 29
Country:
Peru
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lima
Zip:
Lima 32
Country:
Peru
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lima
Zip:
Lima 34
Country:
Peru
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lima
Zip:
LIMA 41
Country:
Peru
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Trujillo
Country:
Peru
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Brzozów
Zip:
36-200
Country:
Poland
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Bydgoszcz
Zip:
85-796
Country:
Poland
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Gdańsk
Zip:
80-952
Country:
Poland
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Koszalin
Zip:
75-581
Country:
Poland
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Poznań
Zip:
60-569
Country:
Poland
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Siedlce
Zip:
08-110
Country:
Poland
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Tomaszów Mazowiecki
Zip:
97-200
Country:
Poland
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Warszawa
Zip:
02-781
Country:
Poland
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Alcabideche
Zip:
2755-009
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Coimbra
Zip:
3000-075
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lisboa
Zip:
1099-023
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lisboa
Zip:
1400-048
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lisboa
Zip:
1769-001
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lisboa
Zip:
1998-018
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Loures
Zip:
2674-514
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Porto
Zip:
4200-319
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Novosibirsk
Zip:
630099
Country:
Russian Federation
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Yekaterinburg
Zip:
620036
Country:
Russian Federation
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Barcelona
Zip:
8003
Country:
Spain
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Barcelona
Zip:
8035
Country:
Spain
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Granada
Zip:
18016
Country:
Spain
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Madrid
Zip:
28034
Country:
Spain
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Madrid
Zip:
28040
Country:
Spain
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Santiago de Compostela
Zip:
15706
Country:
Spain
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Valencia
Zip:
46010
Country:
Spain
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hsinchu
Zip:
300
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taichung
Zip:
402
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taichung
Zip:
40705
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taipei 112
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taipei
Zip:
11490
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taipei
Zip:
23561
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taoyuan City
Zip:
333
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bangkok
Zip:
10300
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bangkok
Zip:
10700
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hat Yai
Zip:
90110
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Khon Kaen
Zip:
40000
Country:
Thailand
Status:
Terminated
Facility:
Name:
Research Site
Address:
City:
Khon Kaen
Zip:
40002
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lampang
Zip:
52000
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Muang
Zip:
22000
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Muang
Zip:
50200
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Mueang
Zip:
20000
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Naimuang
Zip:
30000
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Ankara
Zip:
06010
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Ankara
Zip:
06230
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Ankara
Zip:
06800
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Diyarbakir
Zip:
21280
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Goztepe Istanbul
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Karsiyaka
Zip:
35575
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Chernihiv
Zip:
14029
Country:
Ukraine
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Kharkiv Region
Zip:
61018
Country:
Ukraine
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Kropyvnytskyi
Zip:
25011
Country:
Ukraine
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Kyiv
Zip:
03680
Country:
Ukraine
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Uzhgorod
Zip:
88000
Country:
Ukraine
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Zaporizhzhia
Zip:
69000
Country:
Ukraine
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Belfast
Zip:
BT9 7AB
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bristol
Zip:
BS2 8ED
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Dundee
Zip:
DD1 9SY
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Edinburgh
Zip:
EH4 2XR
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hampshire
Zip:
SO16 6YD
Country:
United Kingdom
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
London
Zip:
NW1 2PG
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
London
Zip:
W6 8RF
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Middlesborough
Zip:
TS4 3BW
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Poole
Zip:
BH15 2JB
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Rhyl
Zip:
LL18 5UJ
Country:
United Kingdom
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Torquay
Zip:
TQ2 7AA
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Truro
Zip:
TR1 3LJ
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Wolverhampton
Zip:
WV10 OQP
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hai Phong
Zip:
180000
Country:
Vietnam
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hanoi
Zip:
100000
Country:
Vietnam
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Ho Chi Minh city
Zip:
700000
Country:
Vietnam
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Ho Chi Minh
Zip:
700000
Country:
Vietnam
Status:
Recruiting
Start date:
February 7, 2022
Completion date:
May 31, 2030
Lead sponsor:
Agency:
AstraZeneca
Agency class:
Industry
Source:
AstraZeneca
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05221840
https://www.lungcancerstudylocator.com/trial/listing/332562
