To hear about similar clinical trials, please enter your email below

Trial Title: Sonography-guided Resection of Brain Mass Lesions

NCT ID: NCT05484245

Condition: Tumor, Brain
Arteriovenous Malformations
Cavernoma
Intracerebral Hematoma

Conditions: Official terms:
Brain Neoplasms
Hemangioma, Cavernous
Cerebral Hemorrhage
Arteriovenous Malformations
Congenital Abnormalities
Hematoma

Conditions: Keywords:
intraoperative sonography
intraoperative ultrasound
brain tumor
cavernoma
arteriovenous malformation
intracerebral hematoma

Study type: Interventional

Study phase: N/A

Overall status: Recruiting

Study design:

Allocation: N/A

Intervention model: Single Group Assignment

Primary purpose: Treatment

Masking: None (Open Label)

Intervention:

Intervention type: Device
Intervention name: Sonography
Description: Surgeon detects brain mass lesion and assesses extent of it's resection with sonography
Arm group label: Surgery

Summary: Objective of the study is to determine possibilities of intraoperative sonography in detecting of various brain mass lesions, assessing extent of their resection and define indications to use ultrasound-guided needle or ultrasound wire-guided port.

Detailed description: Intraoperative sonography is usially used in neurooncology to detect brain tumors and exclude their remnants. A few studies describe it's usage while removing hematomas or vascular malformations. Ultrasound is the only method allowing to observe brain tissue in real time. It is chip and doesn't violate surgical workflow. Main disadvantages of sonography are lengthy learning curve and poorer image quality compared to magnetic resonance imaging. Novel acoustic coupling fluid, contrast-enhanced ultrasound and elastography expanded it's effectiveness. Meanwhile problems of locating of isoechogenic lesions with poor margins and elimination of artefacts are steel actual. Objective of the study is to determine possibilities of intraoperative sonography in detecting of various brain mass lesions, assessing extent of their resection and define indications to use ultrasound-guided needle or ultrasound wire-guided port. A surgeon will intraoperatively locate mass lesion and assess extent of it's resection with sonography. Ultrasound scanning will be performed through the same surgical approach or at a distance through enlarged craniotomy, periodically or permanently. To facilitate approach to subcortical and deep small mass lesions ultrasound-guided needle or ultrasound wire-guided port will be used.

Criteria for eligibility:
Criteria:
Inclusion Criteria: - all intracranial tumors - cavernomas - arteriovenous malformations - spontaneous (non-traumatic) intracerebral hemorrhages - traumatic intracerebral hemorrhages - supratentorial localization - newly diagnosed - age 18-100 years - stable hemodynamics Exclusion Criteria: - rapid cerebral dislocation - previously performed brain radiotherapy

Gender: All

Minimum age: 18 Years

Maximum age: 100 Years

Healthy volunteers: No

Locations:

Facility:
Name: Sklifosovsky Institute of Emergency Care

Address:
City: Moscow
Zip: 129090
Country: Russian Federation

Status: Recruiting

Contact:
Last name: Alexander Dmitriev, MD

Phone: +7 (916) 423-54-08

Start date: September 1, 2022

Completion date: August 31, 2027

Lead sponsor:
Agency: Sklifosovsky Institute of Emergency Care
Agency class: Other

Source: Sklifosovsky Institute of Emergency Care

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT05484245

Login to your account

Did you forget your password?