ORE - 30 Seconds (Oncologists Recommend Exercise in 30 Secs)

Trial Title: ORE - 30 Seconds (Oncologists Recommend Exercise in 30 Secs)

NCT ID: NCT05497544

Condition: Lung Cancer

Conditions: Official terms:
Lung Neoplasms

Study type: Interventional

Study phase: N/A

Overall status: Recruiting

Study design:

Allocation: Randomized

Intervention model: Parallel Assignment

Primary purpose: Supportive Care

Masking: Double (Investigator, Outcomes Assessor)

Intervention:

Intervention type: Behavioral
Intervention name: Exercise recommendation group
Description: A verbal exercise recommendation will be provided. This recommendation will be reported also in the hospital resignation letter.
Arm group label: Exercise recommendation group

Intervention type: Behavioral
Intervention name: Exercise recommendation plus guidebook group
Description: This group will receive the exercise (verbal and written) recommendation. Additionally, the oncologist hand the patient a guidebook about exercise, specifically designed for cancer patients.
Arm group label: Exercise recommendation plus guidebook group

Summary: The O.R.E. - 30 seconds (Oncologists Recommend Exercise in 30 secs) trial aims to test the impact of oncologist recommendations on physical activity level, in patients with lung cancer.

Detailed description: Lung malignancy still remains the leading cause of cancer incidence and mortality worldwide. Despite the improvement in terms of innovative treatments, lung cancer and related therapies continue to be associated with severe physical, psychological, and social side effects. In recent years, several studies have investigated the potential role of physical activity (PA) and exercise (EX) as supportive therapy following a lung cancer diagnosis. Several randomized controlled studies provided evidence that EX is safe for lung cancer patients and may enhance several physiologic and psychologic outcomes. During the preoperative period, EX has demonstrated to increase cardiorespiratory fitness (CRF), and muscular strength, to reduce postoperative complications and length of hospital stay. Following surgery and/or during medical treatments, EX has shown to have a potent modulator effect, able to increase the health-related fitness capacities (especially CRF, muscular strength, and body composition), manage some treatment side effects, such as cancer-related fatigue, sleep disorder and anxiety/depression symptoms. In lung cancer settings, health-related fitness capacities, especially CRF, muscular strength and body composition, are resulted to be prognostic factors. For example, Jones et al. prospectively found that each 50 meters improvement in six minutes walking test (for assessing CRF) was associated with a reduction of 13% in the risk of death in patients with metastatic non-small cell lung cancer. Moreover, some preliminary observational data suggest that higher postdiagnosis PA is associated with lower recurrence, and specific and all-cause mortality in breast, colon, and prostate cancers. American Cancer Society and the American College of Sports Medicine recommend that cancer patients should achieve at least 90 min of moderate-intensity aerobic physical activity each week, with strength and flexibility exercises at least two times per week. Though the EX benefits are remarkable, most lung cancer patients result insufficiently active. Physician counseling has a positive impact on physical activity levels in sedentary adults, and even in the oncological setting can be a crucial key to engaging or improving PA or EX. Lung cancer patients reported that they prefer to receive PA information primarily from oncologists, and this counseling seems effective in improving PA levels. A randomized controlled trial indicated that 30-second oncologist counseling has a modest effect on PA behavior in breast cancer patients. In particular, at five weeks post-consultation, patients that received EX recommendation reported 3.4 metabolic equivalents of the task (MET)-hour of total EX per week (approximately 30 minutes of moderate-intensity) more compared to the usual care group. To date, limited data support the favorable role of oncologist recommendation, with no research focusing on lung cancer settings. To bridge this gap, we propose the O.R.E. - 30 seconds (Oncologists Recommend Exercise in 30 secs) trial to test the impact of oncologist recommendation on physical activity level.

Criteria for eligibility:
Criteria:
Inclusion Criteria: - Confirmed diagnosis of lung cancer (from 0 to 24 months since diagnosis; - Stage I-IV; - Age ≥ 18 years; - ECOG (performance status) ≤ 1; - Written informed consent signed. Exclusion Criteria: - Obvious significant physical or psychological disabilities (e.g., wheelchair, severe anxiety); - Not able to speak, read or write in Italian; - Pregnancy.

Gender: All

Minimum age: 18 Years

Maximum age: N/A

Healthy volunteers: No

Locations:

Facility:
Name: University of Verona

Address:
City: Verona
Zip: 37131
Country: Italy

Status: Recruiting

Contact:
Last name: Alice Avancini

Phone: 3403624264

Phone ext: 39
Email: alice.avancini@univr.it

Start date: July 1, 2022

Completion date: July 1, 2025

Lead sponsor:
Agency: Universita di Verona
Agency class: Other

Source: Universita di Verona

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT05497544