Trial Title:
A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Physician's Choice Chemotherapy in PD-(L)1-refractory, Relapsed or Refractory Classical Hodgkin Lymphoma (MK-4280A-008)
NCT ID:
NCT05508867
Condition:
Hodgkin Lymphoma
Conditions: Official terms:
Lymphoma
Hodgkin Disease
Gemcitabine
Pembrolizumab
Bendamustine Hydrochloride
Conditions: Keywords:
Programmed Cell Death-1 (PD1, PD-1)
Programmed Cell Death 1 Ligand 1 (PDL1, PD-L1)
Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Biological
Intervention name:
favezelimab/pembrolizumab
Description:
Coformulated favezelimab/pembrolizumab (800 mg/200 mg), IV infusion
Arm group label:
Favezelimab/Pembrolizumab
Other name:
MK-4820A
Intervention type:
Drug
Intervention name:
bendamustine
Description:
IV infusion
Arm group label:
Chemotherapy (Bendamustine or Gemcitabine)
Other name:
BENDEKA®
Intervention type:
Drug
Intervention name:
gemcitabine
Description:
IV infusion
Arm group label:
Chemotherapy (Bendamustine or Gemcitabine)
Other name:
GEMZAR®
Summary:
Researchers are looking for a way to treat classical Hodgkin lymphoma (cHL) that is
relapsed (the cancer has come back after treatment) or refractory (current treatment has
stopped working to slow or stop cancer growth). Researchers want to learn if people who
receive coformulated favezelimab/pembrolizumab (MK-4280A) live longer without the cancer
getting worse compared to those who receive chemotherapy.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Has histologically confirmed diagnosis of classical Hodgkin lymphoma (cHL) that is
2-fluorodeoxyglucose-avid (FDG-avid).
- Has relapsed (defined as disease progression after most recent therapy) or
refractory (defined as failed to achieve CR or PR to most recent therapy) cHL and
exhausted all available treatment options with known clinical benefit.
- Has progressed on treatment with an anti-PD-(L)1 monoclonal antibody (mAb)
administered either as monotherapy or in combination with other checkpoint
inhibitors or other therapies.
- Submits an archival (≤5 years) or newly obtained tumor tissue sample which has not
been previously irradiated.
Exclusion Criteria:
- Diagnosis of immunodeficiency or is receiving chronic systemic steroid therapy or
any other form of immunosuppressive therapy.
- History of central nervous system (CNS) metastases or active CNS involvement.
- Has an active autoimmune disease that has required systemic treatment in past 2
years except replacement therapy.
- History of (noninfectious) pneumonitis/interstitial lung disease that required
steroids or has current pneumonitis/interstitial lung disease.
- Has an active infection requiring systemic treatment.
- History of hemophagocytic lymphohisticytosis.
- Has an active seizure disorder that is not well controlled.
- Has clinically significant (ie, active) cardiovascular disease.
- Received prior systemic anticancer therapy including investigational agents within 4
weeks before randomization.
- Received prior radiotherapy within 2 weeks of start of study intervention or
radiation related toxicities requiring corticosteroids.
- Has not adequately recovered from major surgical procedure.
- Known additional malignancy that is progressing or has required active treatment
within the past 3 years.
- History of human immunodeficiency virus (HIV).
- Has had an allogeneic hematopoietic stem cell or solid organ transplantation within
the last 5 years.
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
The University of Arizona Cancer Center - North Campus ( Site 2216)
Address:
City:
Tucson
Zip:
85719
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
520-634-2873
Facility:
Name:
UCLA Hematology/Oncology - Santa Monica ( Site 2208)
Address:
City:
Los Angeles
Zip:
90404
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
310-405-2223
Facility:
Name:
Lundquist Institute for Biomedical Innovation at Harbor-UCLA-Hematology and Medical Oncology ( Site
Address:
City:
Torrance
Zip:
90502
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
310-745-2882
Facility:
Name:
Moffitt Cancer Center ( Site 2200)
Address:
City:
Tampa
Zip:
33612
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
859-797-6639
Facility:
Name:
University of Kentucky Chandler Medical Center ( Site 2201)
Address:
City:
Lexington
Zip:
40536
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
832-443-9325
Facility:
Name:
University of Maryland-Greenebaum Comprehensive Cancer Center ( Site 2210)
Address:
City:
Baltimore
Zip:
21201
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
410-328-6373
Facility:
Name:
Johns Hopkins University-The Sidney Kimmel Comprehensive Cancer Center ( Site 2206)
Address:
City:
Baltimore
Zip:
21231
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
410-502-0882
Facility:
Name:
University of Michigan ( Site 2215)
Address:
City:
Ann Arbor
Zip:
48109
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
908-337-8293
Facility:
Name:
Cancer and Hematology Centers of Western Michigan ( Site 2222)
Address:
City:
Grand Rapids
Zip:
49503
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
616-954-5550
Facility:
Name:
Rutgers Cancer Institute of New Jersey ( Site 2217)
Address:
City:
New Brunswick
Zip:
08903
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
848-448-9972
Facility:
Name:
Roswell Park Cancer Institute ( Site 2220)
Address:
City:
Buffalo
Zip:
14263
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
208-469-9013
Facility:
Name:
University Hospitals Cleveland Medical Center ( Site 2214)
Address:
City:
Cleveland
Zip:
44106
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
216-983-4753
Facility:
Name:
Cleveland Clinic-Taussig Cancer Center ( Site 2203)
Address:
City:
Cleveland
Zip:
44195
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
216-444-0857
Facility:
Name:
AHN West Penn Hospital ( Site 2213)
Address:
City:
Pittsburgh
Zip:
15224
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
585-978-1478
Facility:
Name:
UPMC Hillman Cancer Center ( Site 2205)
Address:
City:
Pittsburgh
Zip:
15232
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
415-572-9678
Facility:
Name:
Fred Hutchinson Cancer Center ( Site 2212)
Address:
City:
Seattle
Zip:
98109
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
617-388-5811
Facility:
Name:
Hospital Aleman-oncohematologic diseases ( Site 2302)
Address:
City:
Buenos Aires
Zip:
C1118AAT
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
005491159820158
Facility:
Name:
Fundacion Centro Oncologico de Integración Regional-Medical Oncology ( Site 2301)
Address:
City:
Mendoza
Zip:
M5500AYB
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+54261-4252575
Facility:
Name:
The Townsville Hospital ( Site 0006)
Address:
City:
Townsville
Zip:
4814
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
6144333549
Facility:
Name:
Royal Adelaide Hospital ( Site 0005)
Address:
City:
Adelaide
Zip:
5000
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
61-8-8222-6934
Facility:
Name:
Western Health-Sunshine & Footscray Hospitals-Cancer Services-Cancer Research ( Site 0002)
Address:
City:
St Albans
Zip:
3021
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
61395944044
Facility:
Name:
Royal Perth Hospital-Haematology ( Site 0004)
Address:
City:
Perth
Zip:
6000
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+61892242405
Facility:
Name:
UZ Leuven-Hematology ( Site 0101)
Address:
City:
Leuven
Zip:
3000
Country:
Belgium
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+32 16 34 25 14
Facility:
Name:
Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godi
Address:
City:
Namur
Zip:
5530
Country:
Belgium
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+3281423831
Facility:
Name:
Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0202)
Address:
City:
Barretos
Zip:
14784400
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
551733216637
Facility:
Name:
Hospital Paulistano-Americas Oncologia ( Site 0207)
Address:
City:
Sao Paulo
Zip:
01321-001
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+5511992926463
Facility:
Name:
Cross Cancer Institute ( Site 0313)
Address:
City:
Edmonton
Zip:
T6G 1Z2
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
17804328757
Facility:
Name:
Princess Margaret Cancer Centre ( Site 0310)
Address:
City:
Toronto
Zip:
M5G 2M9
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
4169464501ext2821
Facility:
Name:
Jewish General Hospital ( Site 0309)
Address:
City:
Montreal
Zip:
H3T 1E2
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5143408222 ext28434
Facility:
Name:
McGill University Health Centre ( Site 0314)
Address:
City:
Montréal
Zip:
H4A 3J1
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5149465451
Facility:
Name:
FALP-UIDO ( Site 0400)
Address:
City:
Santiago
Zip:
7500921
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+56986138945
Facility:
Name:
Clínica Inmunocel ( Site 0407)
Address:
City:
Santiago
Zip:
7580206
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
997890202
Facility:
Name:
Anhui Provincial Cancer Hospital ( Site 0501)
Address:
City:
Hefei
Zip:
230031
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8618900518383
Facility:
Name:
Beijing Hospital ( Site 0514)
Address:
City:
Beijing
Zip:
100005
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13520618812
Facility:
Name:
Peking University Third Hospital-Hematology ( Site 0519)
Address:
City:
Beijing
Zip:
100091
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 15611908428
Facility:
Name:
The First Affiliated hospital of Xiamen University ( Site 0512)
Address:
City:
Xiamen
Zip:
361003
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8618750918842
Facility:
Name:
Sun Yat-sen University Cancer Center-Internal medicine ( Site 0500)
Address:
City:
Guangzhou
Zip:
510060
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13808885154
Facility:
Name:
Henan Cancer Hospital ( Site 0515)
Address:
City:
Zhengzhou
Zip:
450008
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13838176375
Facility:
Name:
Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 0509)
Address:
City:
Wuhan
Zip:
430010
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 02785726114
Facility:
Name:
Xiangya Hospital Central South University ( Site 0513)
Address:
City:
Changsha
Zip:
410008
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13574838611
Facility:
Name:
Hunan Cancer Hospital ( Site 0503)
Address:
City:
Changsha
Zip:
410013
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+8613975879796
Facility:
Name:
The First Hospital of Jilin University-Hematology ( Site 0516)
Address:
City:
Changchun
Zip:
130021
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 15843073208
Facility:
Name:
Fudan University Shanghai Cancer Center ( Site 0520)
Address:
City:
Shanghai
Zip:
200032
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13651603660
Facility:
Name:
West China Hospital of Sichuan University-Head and Neck Oncology ( Site 0502)
Address:
City:
Cheng Du
Zip:
610041
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
028-85422114
Facility:
Name:
Tianjin Medical University Cancer Institute & Hospital-lymphoma ( Site 0506)
Address:
City:
Tianjin
Zip:
300060
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
022-23340123-6416
Facility:
Name:
Zhejiang Cancer Hospital ( Site 0510)
Address:
City:
Hangzhou
Zip:
310022
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13857182590
Facility:
Name:
Ningbo First Hospital ( Site 0518)
Address:
City:
Ningbo
Zip:
315010
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
15968985233
Facility:
Name:
Fakultní nemocnice Brno Bohunice-Interni hematologicka a onkologicka klinika ( Site 0901)
Address:
City:
Brno
Zip:
625 00
Country:
Czechia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
420532233642
Facility:
Name:
Fakultni nemocnice Hradec Kralove-IV. interni hematologicka klinika ( Site 0902)
Address:
City:
Hradec Kralove
Zip:
500 05
Country:
Czechia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
420604813883
Facility:
Name:
Vseobecna fakultni nemocnice v Praze-I. Interní klinika - klinika hematologie ( Site 0903)
Address:
City:
Praha 2
Zip:
128 08
Country:
Czechia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+420 224 962 527
Facility:
Name:
Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou-haematology ( Site 0707)
Address:
City:
Rennes
Zip:
35033
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+33299284191
Facility:
Name:
Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE ( Site 0706)
Address:
City:
Toulouse
Zip:
31059
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
33531156191
Facility:
Name:
Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren ( Site 0704)
Address:
City:
Limoges
Zip:
87042
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
33555058606
Facility:
Name:
Institut Curie - site Saint-Cloud ( Site 0708)
Address:
City:
Saint-Cloud
Zip:
92210
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+33147111530
Facility:
Name:
CENTRE LEON BERARD-Medical oncology ( Site 0703)
Address:
City:
Lyon
Zip:
69008
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+33 4 78 78 26 84
Facility:
Name:
HENRI MONDOR HOSPITAL ( Site 0702)
Address:
City:
Créteil
Zip:
94000
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0149814182
Facility:
Name:
Klinikum Stuttgart - Katharinenhospital ( Site 0804)
Address:
City:
Stuttgart
Zip:
70174
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
004971127835623
Facility:
Name:
Universitaetsklinikum Ulm-Department of Internal Medicine III ( Site 0805)
Address:
City:
Ulm
Zip:
89081
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
49-731-5000
Facility:
Name:
Universitaetsklinikum Essen ( Site 0807)
Address:
City:
Essen
Zip:
45147
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+491631751277
Facility:
Name:
Universitaetsklinikum Koeln-Klinik I für Innere Medizin ( Site 0801)
Address:
City:
Köln
Zip:
50937
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
4922147898888
Facility:
Name:
Universitätsklinikum Münster - Albert Schweitzer Campus ( Site 0806)
Address:
City:
Münster
Zip:
48149
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+492518346010
Facility:
Name:
Universitaetsklinikum Carl Gustav Carus Dresden-University Cancer Center Early Clinical Trial Unit (
Address:
City:
Dresden
Zip:
01307
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
493514582311
Facility:
Name:
Universitätsklinikum Leipzig ( Site 0803)
Address:
City:
Leipzig
Zip:
04103
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
493419713841
Facility:
Name:
Rambam Health Care Campus ( Site 1004)
Address:
City:
Haifa
Zip:
3109601
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
04-7773014
Facility:
Name:
Carmel Hospital ( Site 1007)
Address:
City:
Haifa
Zip:
3436212
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+97248250844
Facility:
Name:
Hadassah Medical Center-Hemato-Oncology ( Site 1000)
Address:
City:
Jerusalem
Zip:
9112001
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
97226776687
Facility:
Name:
Rabin Medical Center-Hemato-Oncology ( Site 1001)
Address:
City:
Petah-Tikva
Zip:
4910021
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
97239378078
Facility:
Name:
Sheba Medical Center-Hemato Oncology ( Site 1005)
Address:
City:
Ramat Gan
Zip:
5265601
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
97235305343
Facility:
Name:
Sourasky Medical Center ( Site 1002)
Address:
City:
Tel Aviv
Zip:
6423906
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
97236973782
Facility:
Name:
Pusan National University Hospital-Internal Medicine ( Site 1704)
Address:
City:
Busan
Zip:
49241
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
821089371258
Facility:
Name:
Seoul National University Hospital ( Site 1701)
Address:
City:
Seoul
Zip:
03080
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+82-2-2072-3559
Facility:
Name:
Severance Hospital, Yonsei University Health System-Medical oncology ( Site 1702)
Address:
City:
Seoul
Zip:
03722
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+82-2-2228-1972
Facility:
Name:
Asan Medical Center-Department of Oncology ( Site 1703)
Address:
City:
Seoul
Zip:
05505
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
82230105940
Facility:
Name:
Samsung Medical Center ( Site 1700)
Address:
City:
Seoul
Zip:
06351
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+82-2-3410-6548
Facility:
Name:
Centro de Infusion Superare ( Site 2503)
Address:
City:
Ciudad de México
Zip:
03100
Country:
Mexico
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5541855489
Facility:
Name:
Unidad Médica Onco-hematológica ( Site 2507)
Address:
City:
Puebla
Zip:
72424
Country:
Mexico
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
2222379880
Facility:
Name:
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckieg-Klinika Hematologii, Nowotworów Krwi i
Address:
City:
Wrocław
Zip:
50-556
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+48793779909
Facility:
Name:
Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie-Oncology Department ( Site 1406)
Address:
City:
Kraków
Zip:
31-826
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+ 48 501 255 521
Facility:
Name:
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Kilinka Onkologii I Hematologii ( Site
Address:
City:
Warszawa
Zip:
02-781
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
22 546 22 23
Facility:
Name:
Uniwersyteckie Centrum Kliniczne-Klinika Hematologii i Transplantologii ( Site 1402)
Address:
City:
Gdansk
Zip:
80-214
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
58 584 43 57
Facility:
Name:
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Hematologii i Transplantacji S
Address:
City:
Kielce
Zip:
25-734
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
48793907806
Facility:
Name:
Hospital Universitario Marqués de Valdecilla ( Site 1805)
Address:
City:
Santander
Zip:
39008
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
942204078
Facility:
Name:
Hospital Universitari Vall d'Hebron ( Site 1803)
Address:
City:
Barcelona
Zip:
08035
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+34 932746000
Facility:
Name:
CHUAC-Complejo Hospitalario Universitario A Coruña ( Site 1812)
Address:
City:
A Coruña
Zip:
15006
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
34981178000
Facility:
Name:
Hospital Insular de Gran Canaria-Oncology ( Site 1807)
Address:
City:
Las Palmas de Gran Canaria
Zip:
35016
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+34 928441738
Facility:
Name:
Hospital General Universitario de Alicante ( Site 1806)
Address:
City:
Alicante
Zip:
03010
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+34611194484
Facility:
Name:
Hospital Universitario 12 de Octubre-Hemathology and hemotherapy ( Site 1810)
Address:
City:
Madrid
Zip:
28041
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
34913908678
Facility:
Name:
Hospital Universitario Virgen de la Victoria ( Site 1808)
Address:
City:
Malaga
Zip:
29010
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
607847416
Facility:
Name:
Hospital Universitario de Salamanca - Complejo Asistencial U-Servicio de Hematologia ( Site 1801)
Address:
City:
Salamanca
Zip:
37007
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
923291100 ext 55974
Facility:
Name:
Skånes Universitetssjukhus Lund ( Site 1901)
Address:
City:
Lund
Zip:
22185
Country:
Sweden
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
004646177858
Facility:
Name:
Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 1900)
Address:
City:
Uppsala
Zip:
751 85
Country:
Sweden
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
46186110213
Facility:
Name:
Ospedale Regionale Bellinzona e Valli-IOSI ( Site 1600)
Address:
City:
Bellinzona
Zip:
6501
Country:
Switzerland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
41918119479
Facility:
Name:
Mega Medipol-Hematology ( Site 2005)
Address:
City:
Stanbul
Zip:
34214
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
05077078197
Facility:
Name:
Ankara Universitesi Tip Fakultesi Hastanesi-hematology ( Site 2000)
Address:
City:
Ankara
Zip:
06100
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
05055025050
Facility:
Name:
Hacettepe Universite Hastaneleri-Department of Hematology ( Site 2006)
Address:
City:
Ankara
Zip:
06230
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
05337203142
Facility:
Name:
Antalya Egitim ve Arastırma Hastanesi ( Site 2011)
Address:
City:
Antalya
Zip:
07100
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5057656778
Facility:
Name:
Ege Universitesi Hastanesi ( Site 2001)
Address:
City:
İzmir
Zip:
35100
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+905325566128
Facility:
Name:
Kocaeli Üniversitesi-Hematology ( Site 2009)
Address:
City:
Kocaeli
Zip:
41380
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
905052591227
Facility:
Name:
Derriford Hospital ( Site 2107)
Address:
City:
Plymouth
Zip:
Pl6 8DH
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
441752431043
Facility:
Name:
The Beatson West of Scotland Cancer Centre ( Site 2110)
Address:
City:
Glasgow
Zip:
G12 0YN
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
07824 437733
Facility:
Name:
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 2105)
Address:
City:
London
Zip:
EC1A 7BE
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
02078828264
Facility:
Name:
GenesisCare - Oxford ( Site 2104)
Address:
City:
Oxford
Zip:
OX4 6LB
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+44 1865 224808
Facility:
Name:
St James's University Hospital ( Site 2109)
Address:
City:
Leeds
Zip:
LS9 7TF
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
111-111-1111
Facility:
Name:
Leicester Royal Infirmary ( Site 2100)
Address:
City:
Leicester
Zip:
LE1 5WW
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+44 808 178 8337
Facility:
Name:
Clatterbridge Cancer Centre - Liverpool-Heamatology ( Site 2108)
Address:
City:
Liverpool
Zip:
L7 8YA
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+447816751178
Start date:
October 18, 2022
Completion date:
June 16, 2031
Lead sponsor:
Agency:
Merck Sharp & Dohme LLC
Agency class:
Industry
Source:
Merck Sharp & Dohme LLC
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05508867
https://www.merckclinicaltrials.com/
https://trialstransparency.merckclinicaltrials.com/Study.aspx?id=4280A-008&kw=4280A-008
