To hear about similar clinical trials, please enter your email below
Trial Title:
Ultrasound-guided Continuous Low Serratus Anterior Plane Block in Hepatocellular Carcinoma Surgery
NCT ID:
NCT05531864
Condition:
Liver Neoplasms
Postoperative Analgesia
Serratus Anterior Plane Block
Conditions: Official terms:
Carcinoma, Hepatocellular
Liver Neoplasms
Conditions: Keywords:
serratus anterior plane block
Postoperative analgesia
liver cancer
Study type:
Interventional
Study phase:
N/A
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Prevention
Masking:
Double (Participant, Outcomes Assessor)
Intervention:
Intervention type:
Procedure
Intervention name:
Ultrasound-guided continuous low serratus anterior plane block
Description:
Low anterior serratus plane block, move the mid-axillary line 4 and 5 intercostal
puncture points are moved down and the puncture is changed to 7 and 8 intercostal.
Arm group label:
Continuous serratus anterior plane block
Intervention type:
Procedure
Intervention name:
Ultrasound-guided single serratus anterior plane block
Description:
Ultrasound-guided single anterior saw plane block was performed, and a needle was
injected between the 4th and 5th costals in the midaxillary line.
Arm group label:
Single serratus anterior plane block combined with rectus sheath nerve block
Summary:
To investigate the clinical application of ultrasound-guided continuous low serratus
anterior plane block in open surgery for hepatocellular carcinoma.
Detailed description:
METHODS: Patients with hepatocellular carcinoma who attended our hospital from January
2021 to April 2023 were divided into CS group and N group according to the random number
table method; CS group underwent ultrasound-guided continuous low anterior serratus plane
block and N group underwent ultrasound-guided single anterior serratus plane block
combined with rectus abdominis sheath block; the operation time, anesthesia time,
incision length, sensory block time and sensory block maintenance time were counted and
recorded. Pain score (NRS) was used to detect analgesia; alanine aminotransferase (ALT),
liver function aspartate aminotransferase (AST), and prothrombin time (The time of
thrombin, NRS) were measured by fluorescent quantitative PCR. （The time of thrombin
(APTT), total bilirubin (TBIL) levels and adverse reactions.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
1. Age 18-60 years;
2. ASAI-II;
3. BMI: 18-29 kg/m2
Exclusion Criteria:
1. Combined cardiac, cerebral, hepatic, and renal failure;
2. Comorbid psychiatric and neuromuscular disorders;
3. A history of allergy to anesthetic drugs;
4. Participation in other recent clinical or drug trials.
Gender:
All
Minimum age:
18 Years
Maximum age:
80 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
The First People's Hospital of Neijiang
Address:
City:
Neijiang
Country:
China
Status:
Recruiting
Contact:
Last name:
Hengchun Shen, master
Phone:
15599237557
Start date:
January 1, 2021
Completion date:
February 29, 2024
Lead sponsor:
Agency:
Liu Di
Agency class:
Other
Source:
The First People's Hospital of Neijiang
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05531864
