Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research

Trial Title: Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research

NCT ID: NCT05539677

Condition: Malignant Solid Tumors
Primary Brain Tumor
Melanoma
Soft Tissue Sarcoma
Colorectal Cancer
Kidney Cancer
Prostate Cancer

Conditions: Official terms:
Neoplasms
Sarcoma
Brain Neoplasms
Kidney Neoplasms

Study type: Observational [Patient Registry]

Overall status: Recruiting

Study design:

Time perspective: Prospective

Summary: The investigators will collect biosamples of patient blood and tumour tissue for further immunological analysis of blood cell subpopulations, immunosupressive factors concentration, HLA expression an lymphocytes and tumour tissue, and and cancer testis antigenes expression on tumour cells, as well as clinical data on patient's stage, therapy, response and demographics. Possible prognostic and predictive dynamic biomarkers will be discovered for individualisation of treatment strategies

Criteria for eligibility:

Study pop:
The study will include patients with solid tumours receiving systemic therapy for their disease who do not have other significant factors that affect the immune system

Sampling method: Probability Sample
Criteria:
Inclusion Criteria: - Signed inform consent - Histolgically verified solid tumour - Receiving systemic therapy for neoplasm - Has archival tumour tissue - Provide biosamples with living tumour tissue or blood samples for immunologic assessment Exclusion Criteria: - Concurrent Lymphoprolipherative disorder - Patients after stem cell or bone marrow thansplantation - Incomplete informaton on previous cancer history or medical history - Patients with known primary immunodeficiency - Patients receiving immunosupressive therapy for concurrent illness - Pregnant patients

Gender: All

Minimum age: 1 Year

Maximum age: N/A

Healthy volunteers: No

Locations:

Facility:
Name: N.N. Petrov NMRC of Oncology, Oncoimmunology dep.

Address:
City: Saint Petersburg
Zip: 197758
Country: Russian Federation

Status: Recruiting

Contact:
Last name: Aleksei Novik, MD, PhD

Phone: +78124399505
Email: alexey.viktorovich.novik@gmail.com

Start date: September 1998

Completion date: December 2030

Lead sponsor:
Agency: N.N. Petrov National Medical Research Center of Oncology
Agency class: Other

Source: N.N. Petrov National Medical Research Center of Oncology

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT05539677